Methyl (Z)-3-amino-4-(2,4,5-trifluorophenyl)but-2-enoate.
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Sitagliptin is an orally available, competitive, beta-amino acid-derived inhibitor of dipeptidyl peptidase 4 (DDP-4) with hypoglycemic activity. Sitagliptin may cause an increased risk in the development of pancreatitis. (Ref. NCI Thesaurus (NCIt) )
Sitagliptin is a dipeptidyl peptidase-4 (DPP-4) inhibitor which is used in combination with diet and exercise in the therapy of type 2 diabetes, either alone or in combination with other oral hypoglycemic agents. (Ref. LiverTox)
Sitagliptin is a triazolopyrazine that exhibits hypoglycemic activity. It has a role as a serine proteinase inhibitor, a hypoglycemic agent, an EC 3.4.14.5 (dipeptidyl-peptidase IV) inhibitor, an environmental contaminant and a xenobiotic. It is a triazolopyrazine and a trifluorobenzene. (Ref.Pub chem)
Sitagliptin API Reference standards and its EP Impurities, USP Impurities, non pharmacopeial Impurities, listed below & also offered custom synthesis for unknown Impurities. If require for any degradation Impurities contact info@drjcrbio.com, sales@drjcrbio.com
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Product Name : Methyl (Z)-3-amino-4-(2,4,5-trifluorophenyl)but-2-enoate;(Z)-Methyl 3-aMino-4-(2,4,5-trifluorophenyl)but-2-enoate |881995-70-6
Code: JCSIT-29 CAS: 881995-70-6 Chemical Formula: C11H10F3NO2 Molecular Weight: 245.2 Category: Reference Standards/API Drug Metabolites/EP Impurities/USP Impurities Literature: Application: Methyl (Z)-3-amino-4-(2,4,5-trifluorophenyl)but-2-enoate;(Z)-Methyl 3-aMino-4-(2,4,5-trifluorophenyl)but-2-enoate |881995-70-6 is useful as reference Impurity standard. 
