6-hydroxy Alosetron HCl; 2,3,4,5-tetrahydro-5-methyl-2-[(5-methyl-1H-imidazo1-4-yl)methyl]-1H-pyrido[4,3-b]-6-hydroxyindol-l-one, mono hydrochloride
Description
Code: JCAST-06 |
CAS: NA |
Chemical Formula: C17H19ClN4O2 |
Molecular Weight: 346.82 |
Category: Reference Standards/API Drug Metabolites/Alosetron EP Impurities/Alosetron USP Impurities |
Literature: Camilleri, M., et al.: Lancet, 355, 1035 (2000), Nestorov, I., et al.: Drug Metab. Dispos., 30, 276 (2002), Lewis, D., et al.: Drug Metab. Rev., 35, 1 (2003), Tang, H., et al.: J. Pharm. Sci., 95, 1783 (2006), Gleeson, M., et al.: J. Med. Chem., 50, 101 (2007) |
Application: 6-hydroxy Alosetron HCl: 2,3,4,5-tetrahydro-5-methyl-2-[(5-methyl-1H-imidazo1-4-yl)methyl]-1H-pyrido[4,3-b]-6-hydroxyindol-l-one, mono hydrochloride useful as reference Impurity standard. |