PHARMA REFERENCES STANDARDS

  • PHARMA INTERMEDITES

  • SERVICES

    Custom Synthesis

    Our team of synthetic chemistry routinely synthesize reference compounds, intermediates, and product candidates from mg to kg scale (including GLP quality) for our clients. Our teams are skilled in both novel route design and route optimization. The team ability to prove outstanding skills in problem solving, our chemists demonstrated proven ability to provide high quality services in an industry leading success rate.

    Process Chemistry

    • Process development
    • Process optimization & validation
    • Process improvement
    • Scale-up
    • Complete process analytic package including impurity profiling & working standards
    • Custom synthesis from grams to kilograms scale
    • Metabolite synthesis
    • Asymmetric synthesis, chiral separation.

    Analytical Services

    Our discovery analytical and purification teams provide high quality analytical and separation services to both internal and external clients. Our experts in this field have built a solid reputation as demonstrated by a high rate of repeat business.

    Impurity Analysis

    • Isolation of impurities of regulatory starting materials, intermediates, APIs and drug products using various techniques including preparative HPLC and SFC
    • Structure elucidation of isolated impurities by acquisition and interpretation of comprehensive 1D/2D NMR and LCMS data
    • Isolation and structure elucidation of forced oxidation degradants of APIs
    • Fast purity determination of raw materials, intermediates, APIs and synthetic impurities by quantitative NMR (QNMR)
    • Professional document preparation for filings

    Phyto-chemicals

    Dr.JCR BIO collaboration with phyto chemical wing outstanding performance and developed more than 70 phyto chemical standards..still working continiously on this path. The capability to isolate single active ingredient or standardized plant extract from natural sources up to kilogram scale. We have an existing collection of purified individual compounds from plants of Indian resources.

    With comprehensive expertise in isolation, purification, analytical method development and synthesis, Dr.JCR BIO, also offers isolation method optimization and development, and structural elucidation service.

    • Milligram-to-kilogram natural product purification capability
    • Isolation process development
    • Quality analysis of pure natural products or crude extracts

    Catalog Chemicals

    Dr.JCR BIO, continuously developing catalog chemicals to reduce the cost and optimization of discovery.   The huge number of research chemicals are listed in our catalog for pharmaceuticals.

    Pls..feel free to contact any inquiry to info@drjcrbio.com or jc@drjcrbio.com