Silodosin

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Silodosin API Reference standards and its EP Impurities, USP Impurities, non pharmacopeial Impurities, listed below & also offered custom synthesis for unknown Impurities. If require any contact info@drjcrbio.com, sales@drjcrbio.com

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    Product Name : Silodosin Indole-N-allyl Impurity; (R)-1-allyl-5-(2-(22-(2,2,2-trifluoroethoxy)phenoxy)ethylamino)propyl)indoline-7-carboxamide

    Code: JCSDS-13
    CAS: NA
    Chemical Formula: C25H30F3N3O3
    Molecular Weight: 477.53
    Category: Reference Standards/API Drug Metabolites/EP Impurities/USP Impurities
    Literature: Shibata, K., et al.: Mol. Pharmacol., 48, 250 (1995); Murata, S., et al.: J. Urol., 164, 578 (2000)
    Application: Silodosin Indole-N-allyl Impurity Silodosin is a metabolite of Silodosin (S465000); an α1a-adrenoceptor antagonist. Also used in the treatment of benign prostatic hypertrophy.
    Silodosin Indole-N-allyl Impurity; (R)-1-allyl-5-(2-(22-(2,2,2-trifluoroethoxy)phenoxy)ethylamino)propyl)indoline-7-carboxamide
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    Product Name : Silodosin ;1-(3-Hydroxypropyl)-5-[(2R)-({2-[2-[2-(2,2,2-trifluoroethoxy)phenoxy] ethyl} amino)propyl]indoline-7-carboxamide | 160970-54-7

    Code: JCSDS-12
    CAS: 160970-54-7
    Chemical Formula: C25H32F3N3O4
    Molecular Weight: 495.53
    Category: Reference Standards/API Drug Metabolites/EP Impurities/USP Impurities
    Literature:
    Application: Silodosin ;1-(3-Hydroxypropyl)-5-[(2R)-({2-[2-[2-(2,2,2-trifluoroethoxy)phenoxy] ethyl} amino)propyl]indoline-7-carboxamide | 160970-54-7 is useful as reference Impurity standard.
    Silodosin ;1-(3-Hydroxypropyl)-5-[(2R)-({2-[2-[2-(2,2,2-trifluoroethoxy)phenoxy] ethyl} amino)propyl]indoline-7-carboxamide   |  160970-54-7
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    Product Name : Silodosin (S)-Isomer ;1-(3-Hydroxypropyl)-5-[(2S)-({2-[2-[2-(2,2,2-trifluoroethoxy)phenoxy] ethyl} amino)propyl]indoline-7-carboxamide

    Code: JCSDS-11
    CAS:  NA
    Chemical Formula: C25H32F3N3O4
    Molecular Weight: 495.53
    Category: Reference Standards/API Drug Metabolites/EP Impurities/USP Impurities
    Literature:
    Application: Silodosin (S)-Isomer ;1-(3-Hydroxypropyl)-5-[(2S)-({2-[2-[2-(2,2,2-trifluoroethoxy)phenoxy] ethyl} amino)propyl]indoline-7-carboxamide is useful as reference Impurity standard.
    Silodosin (S)-Isomer ;1-(3-Hydroxypropyl)-5-[(2S)-({2-[2-[2-(2,2,2-trifluoroethoxy)phenoxy] ethyl} amino)propyl]indoline-7-carboxamide
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    Product Name : Silodosin Dehydro Impurity ;(R)-1-(3-Hydroxypropyl)-5-(2-(2-(2-(2,2,2-trifluoroethoxy)phenoxy)ethylamino)propyl)-1H-indole-7-carboxamide | 175870-21-0

    Code: JCSDS-10
    CAS: 175870-21-0
    Chemical Formula: C25H30F3N3O4
    Molecular Weight: 493.52
    Category: Reference Standards/API Drug Metabolites/EP Impurities/USP Impurities
    Literature:
    Application: Silodosin Dehydro Impurity ;(R)-1-(3-Hydroxypropyl)-5-(2-(2-(2-(2,2,2-trifluoroethoxy)phenoxy)ethylamino)propyl)-1H-indole-7-carboxamide | 175870-21-0 is useful as reference Impurity standard.
    Silodosin Dehydro Impurity ;(R)-1-(3-Hydroxypropyl)-5-(2-(2-(2-(2,2,2-trifluoroethoxy)phenoxy)ethylamino)propyl)-1H-indole-7-carboxamide  |  175870-21-0
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    Product Name : Silodosin Carboxylic Acid Impurity ;(R)-3-(7-Carbamoyl-5-(2-(2-(2-(2,2,2-trifluoroethoxy)phenoxy)ethylamino) propyl)indolin-1-yl)propanoic acid | 1357252-79-9

    Code: JCSDS-09
    CAS: 1357252-79-9
    Chemical Formula: C25H30F3N3O5
    Molecular Weight: 509.52
    Category: Reference Standards/API Drug Metabolites/EP Impurities/USP Impurities
    Literature:
    Application: Silodosin Carboxylic Acid Impurity ;(R)-3-(7-Carbamoyl-5-(2-(2-(2-(2,2,2-trifluoroethoxy)phenoxy)ethylamino) propyl)indolin-1-yl)propanoic acid | 1357252-79-9 is useful as reference Impurity standard.
    Silodosin Carboxylic Acid Impurity ;(R)-3-(7-Carbamoyl-5-(2-(2-(2-(2,2,2-trifluoroethoxy)phenoxy)ethylamino) propyl)indolin-1-yl)propanoic acid  |  1357252-79-9
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    Product Name : Silodosin Nitrile Impurity ;(R)-1-(3-Hydroxypropyl)-5-(2-(2-(2-(2,2,2-trifluoroethoxy)phenoxy) ethylamino)propyl)indoline-7-carbonitrile | 885340-13-6

    Code: JCSDS-08
    CAS: 885340-13-6
    Chemical Formula:C25H30F3N3O3
    Molecular Weight: 477.52
    Category: Reference Standards/API Drug Metabolites/EP Impurities/USP Impurities
    Literature:
    Application: Silodosin Nitrile Impurity ;(R)-1-(3-Hydroxypropyl)-5-(2-(2-(2-(2,2,2-trifluoroethoxy)phenoxy) ethylamino)propyl)indoline-7-carbonitrile | 885340-13-6 is useful as reference Impurity standard.
    Silodosin Nitrile Impurity ;(R)-1-(3-Hydroxypropyl)-5-(2-(2-(2-(2,2,2-trifluoroethoxy)phenoxy) ethylamino)propyl)indoline-7-carbonitrile  |  885340-13-6
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    Product Name : Silodosin Deshydroxypropyl Impurity ; (R)-5-(2-((2-(2-(2,2,2-Trifluoroethoxy)phenoxy)ethyl)amino)propyl)indoline-7-carboxamide

    Code: JCSDS-07
    CAS: NA
    Chemical Formula: C22H26F3N3O3
    Molecular Weight: 437.46
    Category: Reference Standards/API Drug Metabolites/EP Impurities/USP Impurities
    Literature:
    Application: Silodosin Deshydroxypropyl Impurity ; (R)-5-(2-((2-(2-(2,2,2-Trifluoroethoxy)phenoxy)ethyl)amino)propyl)indoline-7-carboxamide is useful as reference Impurity standard.
    Silodosin Deshydroxypropyl Impurity ; (R)-5-(2-((2-(2-(2,2,2-Trifluoroethoxy)phenoxy)ethyl)amino)propyl)indoline-7-carboxamide
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    Product Name : Silodosin Dimer Impurity ; (R)-1-(3-Hydroxypropyl)-5-(2-((2-(2-(2,2,2-trifluoroethoxy)phenoxy)ethyl) (2-(2-(2,2,2-trifluoroethyl)phenoxy)ethyl)amino)propyl)indoline-7-carboxamide | 1453221-45-8

    Code: JCSDS-06
    CAS: 1453221-45-8
    Chemical Formula: C35H41F6N3O6
    Molecular Weight: 713.71
    Category: Reference Standards/API Drug Metabolites/EP Impurities/USP Impurities
    Literature:
    Application: Silodosin Dimer Impurity ; (R)-1-(3-Hydroxypropyl)-5-(2-((2-(2-(2,2,2-trifluoroethoxy)phenoxy)ethyl) (2-(2-(2,2,2-trifluoroethyl)phenoxy)ethyl)amino)propyl)indoline-7-carboxamide | 1453221-45-8 is useful as reference Impurity standard.
    Silodosin Dimer Impurity ; (R)-1-(3-Hydroxypropyl)-5-(2-((2-(2-(2,2,2-trifluoroethoxy)phenoxy)ethyl) (2-(2-(2,2,2-trifluoroethyl)phenoxy)ethyl)amino)propyl)indoline-7-carboxamide  |  1453221-45-8
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    Product Name : Silodosin Glucuronide ; Silodosin β-D-Glucuronide ;3-[7-(Aminocarbonyl)-2,3-dihydro-5-[(2R)-2-[[2-[2-(2,2,2-trifluoroethoxy)phenoxy]ethyl]amino]propyl]-1H-indol-1-yl]propyl β-D-glucopyranosiduronic acid | 879396-70-0

    Code: JCSDS-05
    CAS: 879396-70-0
    Chemical Formula: C31H40F3N3O10
    Molecular Weight: 671.66
    Category: Reference Standards/API Drug Metabolites/EP Impurities/USP Impurities
    Literature:
    Application: Silodosin Glucuronide ; Silodosin β-D-Glucuronide ;3-[7-(Aminocarbonyl)-2,3-dihydro-5-[(2R)-2-[[2-[2-(2,2,2-trifluoroethoxy)phenoxy]ethyl]amino]propyl]-1H-indol-1-yl]propyl β-D-glucopyranosiduronic acid | 879396-70-0 is useful as reference Impurity standard.
    Silodosin Glucuronide ; Silodosin β-D-Glucuronide ;3-[7-(Aminocarbonyl)-2,3-dihydro-5-[(2R)-2-[[2-[2-(2,2,2-trifluoroethoxy)phenoxy]ethyl]amino]propyl]-1H-indol-1-yl]propyl β-D-glucopyranosiduronic acid  |  879396-70-0
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    Product Name : Silodosin N-Oxide ;1-(3-Hydroxypropyl)-5-[(2R)-({2-[2-[2-(2,2,2-trifluoroethoxy)phenoxy] ethyl} amino)propyl]indoline-7-carboxamide N-oxide

    Code: JCSDS-04
    CAS: NA
    Chemical Formula: C25H32F3N3O5
    Molecular Weight: 511.53
    Category: Reference Standards/API Drug Metabolites/EP Impurities/USP Impurities
    Literature:
    Application: Silodosin N-Oxide ;1-(3-Hydroxypropyl)-5-[(2R)-({2-[2-[2-(2,2,2-trifluoroethoxy)phenoxy] ethyl} amino)propyl]indoline-7-carboxamide N-oxide is useful as reference Impurity standard.
    Silodosin N-Oxide ;1-(3-Hydroxypropyl)-5-[(2R)-({2-[2-[2-(2,2,2-trifluoroethoxy)phenoxy] ethyl} amino)propyl]indoline-7-carboxamide N-oxide
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    Product Name : Silodosin Nitro Impurity ;3-(7-Cyano-5-(2-nitropropyl)indolin-1-yl)propyl Benzoate ; 1-[3-(Benzoyloxy)propyl]-2,3-dihydro-5-(2-nitropropyl)-1H-Indole-7-carbonitrile | 350797-56-7

    Code: JCSDS-03
    CAS: 350797-56-7
    Chemical Formula: C22H23N3O4
    Molecular Weight: 393.44
    Category: Reference Standards/API Drug Metabolites/EP Impurities/USP Impurities
    Literature:
    Application: Silodosin Nitro Impurity ;3-(7-Cyano-5-(2-nitropropyl)indolin-1-yl)propyl Benzoate ; 1-[3-(Benzoyloxy)propyl]-2,3-dihydro-5-(2-nitropropyl)-1H-Indole-7-carbonitrile | 350797-56-7 is useful as reference Impurity standard.
    Silodosin Nitro Impurity ;3-(7-Cyano-5-(2-nitropropyl)indolin-1-yl)propyl Benzoate ; 1-[3-(Benzoyloxy)propyl]-2,3-dihydro-5-(2-nitropropyl)-1H-Indole-7-carbonitrile  |  350797-56-7
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    Product Name : Silodosin O-Acetyl Impurity;(R)-1-[3-(Acetyloxy)propyl]-2,3-dihydro-5-[2-[[2-[2-(2,2,2-trifluoroethoxy)phenoxy] ethyl]amino]propyl]-1H-Indole-7-carboxamide | 160970-86-5

    Code: JCSDS-02
    CAS: 160970-86-5
    Chemical Formula: C27H34F3N3O5
    Molecular Weight: 537.57
    Category: Reference Standards/API Drug Metabolites/EP Impurities/USP Impurities
    Literature:
    Application: Silodosin O-Acetyl Impurity;(R)-1-[3-(Acetyloxy)propyl]-2,3-dihydro-5-[2-[[2-[2-(2,2,2-trifluoroethoxy)phenoxy] ethyl]amino]propyl]-1H-Indole-7-carboxamide | 160970-86-5 is useful as reference Impurity standard.
    Silodosin O-Acetyl Impurity;(R)-1-[3-(Acetyloxy)propyl]-2,3-dihydro-5-[2-[[2-[2-(2,2,2-trifluoroethoxy)phenoxy] ethyl]amino]propyl]-1H-Indole-7-carboxamide  |  160970-86-5
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    Product Name : Silodosin Racemate ;1-(3-Hydroxypropyl)-5-[({2-[2-[2-(2,2,2-trifluoroethoxy)phenoxy] ethyl} amino)propyl]indoline-7-carboxamide | 160970-64-9

    Code: JCSDS-01
    CAS: 160970-64-9
    Chemical Formula: C25H32F3N3O4
    Molecular Weight: 495.53
    Category: Reference Standards/API Drug Metabolites/EP Impurities/USP Impurities
    Literature:
    Application: Silodosin Racemate ;1-(3-Hydroxypropyl)-5-[({2-[2-[2-(2,2,2-trifluoroethoxy)phenoxy] ethyl} amino)propyl]indoline-7-carboxamide | 160970-64-9 is useful as reference Impurity standard.
    Silodosin Racemate ;1-(3-Hydroxypropyl)-5-[({2-[2-[2-(2,2,2-trifluoroethoxy)phenoxy] ethyl} amino)propyl]indoline-7-carboxamide  |  160970-64-9