Rotigotine

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Rotigotine API Reference standards and its EP Impurities, USP Impurities, non pharmacopeial Impurities, listed below & also offered custom synthesis for unknown Impurities. If require any contact info@drjcrbio.com, sales@drjcrbio.com

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    Product Name : Rotigotine Racemate HCl ;5,6,7,8-Tetrahydro-6-[propyl[2-(2-thienyl)ethyl]amino]-1-naphthalenol HCl |102120-99-0

    Code: JCROT-15
    CAS: 102120-99-0
    Chemical Formula:C19H26ClNOS
    Molecular Weight:351.93
    Category: Reference Standards/API Drug Metabolites/EP Impurities/USP Impurities
    Literature:
    Application:  Rotigotine Racemate HCl ;5,6,7,8-Tetrahydro-6-[propyl[2-(2-thienyl)ethyl]amino]-1-naphthalenol HCl |102120-99-0 is useful as reference Impurity standard.
    Rotigotine Racemate HCl ;5,6,7,8-Tetrahydro-6-[propyl[2-(2-thienyl)ethyl]amino]-1-naphthalenol HCl |102120-99-0
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    Product Name : Rotigotine EP Impurity K ;Rotigotine USP RC K ; 7,8-Dihydronaphthalen-1-ol| 51927-48-1

    Code: JCROT-14
    CAS: 51927-48-1
    Chemical Formula:C10H10O
    Molecular Weight:146.19
    Category: Reference Standards/API Drug Metabolites/EP Impurities/USP Impurities
    Literature:
    Application:   is useful as reference Impurity standard.
    Rotigotine EP Impurity K ;Rotigotine USP RC K ;  7,8-Dihydronaphthalen-1-ol| 51927-48-1
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    Product Name : Rotigotine EP Impurity J ;Rotigotine Thienylethyl Ether ; (2S)-N-propyl-5-[2-(thiophen-2-yl)ethoxy]-N-[2-(thiophen-2-yl)ethyl]-1,2,3,4-tetrahydronaphthalen-2-amine ;

    Code: JCROT-13
    CAS: NA
    Chemical Formula:C26H31NO3S2
    Molecular Weight:469.66
    Category: Reference Standards/API Drug Metabolites/EP Impurities/USP Impurities
    Literature:
    Application:   Rotigotine EP Impurity J ;Rotigotine Thienylethyl Ether ; (2S)-N-propyl-5-[2-(thiophen-2-yl)ethoxy]-N-[2-(thiophen-2-yl)ethyl]-1,2,3,4-tetrahydronaphthalen-2-amine ;is useful as reference Impurity standard.
    Rotigotine EP Impurity J ;Rotigotine Thienylethyl Ether ;  (2S)-N-propyl-5-[2-(thiophen-2-yl)ethoxy]-N-[2-(thiophen-2-yl)ethyl]-1,2,3,4-tetrahydronaphthalen-2-amine ;
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    Product Name : Rotigotine EP Impurity I (Oxalate) ;Rotigotine Toluene Sulfonic Acid Ester (Oxalate) ; (6S)-6-[Propyl[2-(thiophen-2-yl)ethyl]amino]-5,6,7,8-tetrahydronaphthalen-1-yl 4-methylbenzenesulfonate oxalate ;

    Code: JCROT-12
    CAS: NA
    Chemical Formula:C26H31NO3S2 (Base) ; C28H33NO7S2 (Oxalate)
    Molecular Weight:469.66 ; 559.69
    Category: Reference Standards/API Drug Metabolites/EP Impurities/USP Impurities
    Literature:
    Application:  Rotigotine EP Impurity I (Oxalate) ;Rotigotine Toluene Sulfonic Acid Ester (Oxalate) ; (6S)-6-[Propyl[2-(thiophen-2-yl)ethyl]amino]-5,6,7,8-tetrahydronaphthalen-1-yl 4-methylbenzenesulfonate oxalate ; is useful as reference Impurity standard.
    Rotigotine EP Impurity I (Oxalate) ;Rotigotine Toluene Sulfonic Acid Ester (Oxalate) ;  (6S)-6-[Propyl[2-(thiophen-2-yl)ethyl]amino]-5,6,7,8-tetrahydronaphthalen-1-yl 4-methylbenzenesulfonate oxalate ;
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    Product Name : Rotigotine EP Impurity H (Oxalate) ;Rotigotine USP RC H ; O-Methyl Rotigotine Oxalate ; (S)-5-Methoxy-N-propyl-N-[2-(thiophen-2-yl)ethyl]-1,2,3,4-tetrahydronaphthalen-2-amine oxalate |1148154-91-9 (Base)

    Code: JCROT-11
    CAS: 1148154-91-9 (Base)
    Chemical Formula:C20H27NOS (Base);C22H29NO5S (Oxalate)
    Molecular Weight:329.50(Base);419.53(Oxalate)
    Category: Reference Standards/API Drug Metabolites/EP Impurities/USP Impurities
    Literature:
    Application:   Rotigotine EP Impurity H (Oxalate) ;Rotigotine USP RC H ; O-Methyl Rotigotine Oxalate ; (S)-5-Methoxy-N-propyl-N-[2-(thiophen-2-yl)ethyl]-1,2,3,4-tetrahydronaphthalen-2-amine oxalate |1148154-91-9 (Base)is useful as reference Impurity standard.
    Rotigotine EP Impurity H (Oxalate) ;Rotigotine USP RC H ;  O-Methyl Rotigotine Oxalate ;  (S)-5-Methoxy-N-propyl-N-[2-(thiophen-2-yl)ethyl]-1,2,3,4-tetrahydronaphthalen-2-amine oxalate |1148154-91-9 (Base)
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    Product Name : Rotigotine EP Impurity G (HCl) ;Rotigotine USP RC G ; (S)-6-{Bis[2-(thiophen-2-yl)ethyl]amino}-5,6,7,8-tetrahydronaphthalen-1-ol hydrochloride | 1369532-05-7 ;

    Code: JCROT-10
    CAS: 1369532-05-7
    Chemical Formula:C22H26ClNOS2
    Molecular Weight:420.03
    Category: Reference Standards/API Drug Metabolites/EP Impurities/USP Impurities
    Literature:
    Application:  Rotigotine EP Impurity G (HCl) ;Rotigotine USP RC G ; (S)-6-{Bis[2-(thiophen-2-yl)ethyl]amino}-5,6,7,8-tetrahydronaphthalen-1-ol hydrochloride | 1369532-05-7 ; is useful as reference Impurity standard.
    Rotigotine EP Impurity G (HCl) ;Rotigotine USP RC G ;  (S)-6-{Bis[2-(thiophen-2-yl)ethyl]amino}-5,6,7,8-tetrahydronaphthalen-1-ol hydrochloride | 1369532-05-7 ;
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    Product Name : Rotigotine EP Impurity F (Oxalate) ;O-Acetyl Rotigotine Oxalate ; (6S)-6-[Propyl[2-(thiophen-2-yl)ethyl]amino]-5,6,7,8-tetrahydronaphthalen-1-yl acetate oxalate| 835654-68-7 (Base)

    Code: JCROT-09
    CAS: 835654-68-7 (Base)
    Chemical Formula:C21H27NO2S (Base) ;  C23H29NO6S (Oxalate)
    Molecular Weight:357.51 (Base) ;  447.54(Oxalate)
    Category: Reference Standards/API Drug Metabolites/EP Impurities/USP Impurities
    Literature:
    Application:  Rotigotine EP Impurity F (Oxalate) ;O-Acetyl Rotigotine Oxalate ; (6S)-6-[Propyl[2-(thiophen-2-yl)ethyl]amino]-5,6,7,8-tetrahydronaphthalen-1-yl acetate oxalate| 835654-68-7 (Base) is useful as reference Impurity standard.
    Rotigotine EP Impurity F (Oxalate) ;O-Acetyl Rotigotine Oxalate ;  (6S)-6-[Propyl[2-(thiophen-2-yl)ethyl]amino]-5,6,7,8-tetrahydronaphthalen-1-yl acetate oxalate| 835654-68-7 (Base)
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    Product Name : Rotigotine EP Impurity E (Base) ; Rotigotine N-Oxide ; (2S)-5-Hydroxy-N-propyl-N-[2-(thiophen-2-yl)ethyl]-1,2,3,4-tetrahydronaphthalen-2-amine N-oxide ;

    Code: JCROT-08
    CAS: NA
    Chemical Formula:C19H25NO2S
    Molecular Weight:331.47
    Category: Reference Standards/API Drug Metabolites/EP Impurities/USP Impurities
    Literature:
    Application:  Rotigotine EP Impurity E (Base) ; Rotigotine N-Oxide ; (2S)-5-Hydroxy-N-propyl-N-[2-(thiophen-2-yl)ethyl]-1,2,3,4-tetrahydronaphthalen-2-amine N-oxide ; is useful as reference Impurity standard.
    Rotigotine EP Impurity E (Base) ; Rotigotine N-Oxide ;  (2S)-5-Hydroxy-N-propyl-N-[2-(thiophen-2-yl)ethyl]-1,2,3,4-tetrahydronaphthalen-2-amine N-oxide ;
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    Product Name : Rotigotine EP Impurity D ;Ethyl Rotigotine ; (6S)-6-[Ethyl[2-(thiophen-2-yl)ethyl]amino]-5,6,7,8-tetrahydronaphthalen-1-ol | 1369625-04-6 ;

    Code: JCROT-07
    CAS: 1369625-04-6
    Chemical Formula:C18H23NOS
    Molecular Weight:301.45
    Category: Reference Standards/API Drug Metabolites/EP Impurities/USP Impurities
    Literature:
    Application:  Rotigotine EP Impurity D ;Ethyl Rotigotine ; (6S)-6-[Ethyl[2-(thiophen-2-yl)ethyl]amino]-5,6,7,8-tetrahydronaphthalen-1-ol | 1369625-04-6 ; is useful as reference Impurity standard.
    Rotigotine EP Impurity D ;Ethyl Rotigotine ;  (6S)-6-[Ethyl[2-(thiophen-2-yl)ethyl]amino]-5,6,7,8-tetrahydronaphthalen-1-ol | 1369625-04-6 ;
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    Product Name : Rotigotine EP Impurity C (HCl) ; Rotigotine USP RC C ; N-Despropyl Rotigotine HCl ; (6S)-5,6,7,8-Tetrahydro-6-[[2-(2-thienyl)ethyl]amino]-1-naphthalenol HCl | 153409-14-4 (base)

    Code: JCROT-06
    CAS: 153409-14-4 (base)
    Chemical Formula:C16H19NOS
    Molecular Weight:273.39
    Category: Reference Standards/API Drug Metabolites/EP Impurities/USP Impurities
    Literature:
    Application:  Rotigotine EP Impurity C (HCl) ; Rotigotine USP RC C ; N-Despropyl Rotigotine HCl ; (6S)-5,6,7,8-Tetrahydro-6-[[2-(2-thienyl)ethyl]amino]-1-naphthalenol HCl | 153409-14-4 (base) is useful as reference Impurity standard.
    Rotigotine EP Impurity C (HCl) ; Rotigotine USP RC C ;  N-Despropyl Rotigotine HCl ;  (6S)-5,6,7,8-Tetrahydro-6-[[2-(2-thienyl)ethyl]amino]-1-naphthalenol HCl | 153409-14-4 (base)
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    Product Name : Rotigotine EP Impurity B (HCl) ; N-Desthienylethyl Rotigotine HCl ; (S)-6-(Propylamino)-5,6,7,8-tetrahydronaphthalen-1-ol HCl ; | 101470-23-9 (Base) ;

    Code: JCROT-05
    CAS: 101470-23-9 (Base)
    Chemical Formula:C13H19NO (Base)  ; C13H20ClNO (HCl)
    Molecular Weight:205.30(Base) ; 241.76(HCl)
    Category: Reference Standards/API Drug Metabolites/EP Impurities/USP Impurities
    Literature:
    Application:  Rotigotine EP Impurity B (HCl) ; N-Desthienylethyl Rotigotine HCl ; (S)-6-(Propylamino)-5,6,7,8-tetrahydronaphthalen-1-ol HCl ; | 101470-23-9 (Base) ; is useful as reference Impurity standard.
    Rotigotine EP Impurity B (HCl) ; N-Desthienylethyl Rotigotine HCl ;  (S)-6-(Propylamino)-5,6,7,8-tetrahydronaphthalen-1-ol HCl ; |  101470-23-9 (Base) ;
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    Product Name : Rotigotine EP Impurity A (HCl) ; Rotigotine HCl (R)-Isomer ; ent-Rotigotine HCl ; (6R)-5,6,7,8-Tetrahydro-6-[propyl[2-(2-thienyl)ethyl]amino]-1-naphthalenol HCl | 112835-48-0 (Base) ;

    Code: JCROT-04
    CAS: 112835-48-0 (Base)
    Chemical Formula:C19H25NOS (Base) ; C19H26ClNOS (HCl)
    Molecular Weight:315.47(Base); 351.93 (HCl)
    Category: Reference Standards/API Drug Metabolites/EP Impurities/USP Impurities
    Literature:
    Application:  Rotigotine EP Impurity A (HCl) ; Rotigotine HCl (R)-Isomer ; ent-Rotigotine HCl ; (6R)-5,6,7,8-Tetrahydro-6-[propyl[2-(2-thienyl)ethyl]amino]-1-naphthalenol HCl | 112835-48-0 (Base) ; is useful as reference Impurity standard.
    Rotigotine EP Impurity A (HCl) ; Rotigotine HCl (R)-Isomer ;  ent-Rotigotine HCl ;  (6R)-5,6,7,8-Tetrahydro-6-[propyl[2-(2-thienyl)ethyl]amino]-1-naphthalenol HCl   | 112835-48-0 (Base) ;
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    Product Name : Rotigotine (HCl) ; Rotigotine Hydrochloride ; (6S)-5,6,7,8-Tetrahydro-6-[propyl[2-(2-thienyl)ethyl]amino]-1-naphthalenol HCl |125572-93-2

    Code: JCROT-03
    CAS: 125572-93-2
    Chemical Formula:C19H26ClNOS
    Molecular Weight:351.93
    Category: Reference Standards/API Drug Metabolites/EP Impurities/USP Impurities
    Literature:
    Application:   Rotigotine (HCl) ; Rotigotine Hydrochloride ; (6S)-5,6,7,8-Tetrahydro-6-[propyl[2-(2-thienyl)ethyl]amino]-1-naphthalenol HCl |125572-93-2 is useful as reference Impurity standard.
    Rotigotine (HCl) ; Rotigotine Hydrochloride ;  (6S)-5,6,7,8-Tetrahydro-6-[propyl[2-(2-thienyl)ethyl]amino]-1-naphthalenol HCl |125572-93-2
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    Product Name : Rotigotine (Base) ; (6S)-5,6,7,8-Tetrahydro-6-[propyl[2-(2-thienyl)ethyl]amino]-1-naphthalenol |99755-59-6 ;

    Code: JCROT-02
    CAS: 99755-59-6
    Chemical Formula:C19H25NOS
    Molecular Weight:315.47
    Category: Reference Standards/API Drug Metabolites/EP Impurities/USP Impurities
    Literature:
    Application:  Rotigotine (Base) ; (6S)-5,6,7,8-Tetrahydro-6-[propyl[2-(2-thienyl)ethyl]amino]-1-naphthalenol |99755-59-6 ; is useful as reference Impurity standard.
    Rotigotine (Base) ; (6S)-5,6,7,8-Tetrahydro-6-[propyl[2-(2-thienyl)ethyl]amino]-1-naphthalenol  |99755-59-6 ;
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    Product Name : Rotigotine β-D-Glucuronide ; (S)-5,6,7,8-Tetrahydro-6-[propyl[2-(2-thienyl)ethyl]amino]-1-naphthalenyl β-D-glucopyranosiduronic acid |128464-29-9

    Code: JCROT-01
    CAS: 128464-29-9
    Chemical Formula:C25H33NO7S
    Molecular Weight:491.60
    Category: Reference Standards/API Drug Metabolites/EP Impurities/USP Impurities
    Literature:
    Application:   Rotigotine β-D-Glucuronide ; (S)-5,6,7,8-Tetrahydro-6-[propyl[2-(2-thienyl)ethyl]amino]-1-naphthalenyl β-D-glucopyranosiduronic acid |128464-29-9is useful as reference Impurity standard.
    Rotigotine β-D-Glucuronide ; (S)-5,6,7,8-Tetrahydro-6-[propyl[2-(2-thienyl)ethyl]amino]-1-naphthalenyl β-D-glucopyranosiduronic acid |128464-29-9