Ribociclib
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Ribociclib API Reference standards and its EP Impurities, USP Impurities, non pharmacopeial Impurities, listed below & also offered custom synthesis for unknown Impurities. If require any contact info@drjcrbio.com, sales@drjcrbio.com
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Product Name : Ribociclib Impurity 11; 7-cyclopentyl-N,N-dimethyl-2-((5-(4-nitrosopiperazin-1-yl)pyridin-2-yl)amino)-7H-pyrrolo[2,3-d]pyrimidine-6-carboxamide
Code: JCNTS-N288 CAS: N/A Chemical Formula: C23H29N9O2 Molecular Weight: 463.54 Category: Ribociclib Nitroso amine API Drug Metabolites/nitroso amine EP Impurities/nitroso amine USP ImpuritiesLiterature: Application: Ribociclib Impurity 11; 7-cyclopentyl-N,N-dimethyl-2-((5-(4-nitrosopiperazin-1-yl)pyridin-2-yl)amino)-7H-pyrrolo[2,3-d]pyrimidine-6-carboxamide is useful as reference Impurity standard. ![Ribociclib Impurity 11; 7-cyclopentyl-N,N-dimethyl-2-((5-(4-nitrosopiperazin-1-yl)pyridin-2-yl)amino)-7H-pyrrolo[2,3-d]pyrimidine-6-carboxamide](https://drjcrbio.com/wp-content/uploads/Ribociclib-Impurity-11-7-cyclopentyl-NN-dimethyl-2-5-4-nitrosopiperazin-1-ylpyridin-2-ylamino-7H-pyrrolo23-dpyrimidine-6-carboxamide.jpg)
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Product Name : Ribociclib chloro Impurity; 5-chloro-7-cyclopentyl-N,N-dimethyl-2-((5-(piperazin-1-yl)pyridin-2-yl)amino)-7H-pyrrolo[2,3-d]pyrimidine-6-carboxamide
Code: JCRCB-18 CAS: NA Chemical Formula: C23H29ClN8O Molecular Weight: 468.99 Category: Ribociclib Reference Standards/API Drug Metabolites/EP Impurities/USP Impurities Literature: Application: Ribociclib chloro Impurity; 5-chloro-7-cyclopentyl-N,N-dimethyl-2-((5-(piperazin-1-yl)pyridin-2-yl)amino)-7H-pyrrolo[2,3-d]pyrimidine-6-carboxamide is useful as reference Impurity standard. ![Ribociclib chloro Impurity; 5-chloro-7-cyclopentyl-N,N-dimethyl-2-((5-(piperazin-1-yl)pyridin-2-yl)amino)-7H-pyrrolo[2,3-d]pyrimidine-6-carboxamide](https://drjcrbio.com/wp-content/uploads/Ribociclib-chloro-Impurity-5-chloro-7-cyclopentyl-NN-dimethyl-2-5-piperazin-1-ylpyridin-2-ylamino-7H-pyrrolo23-dpyrimidine-6-carboxamide.png)
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Product Name : Ribociclib N-desmethyl Impurity; 7-cyclopentyl-N-methyl-2-((5-(piperazin-1-yl)pyridin-2-yl)amino)-7H-pyrrolo[2,3-d]pyrimidine-6-carboxamide
Code: JCRCB-17 CAS: NA Chemical Formula: C22H28N8O Molecular Weight: 420.52 Category: Ribociclib Reference Standards/API Drug Metabolites/EP Impurities/USP Impurities Literature: Application: Ribociclib N-desmethyl Impurity; 7-cyclopentyl-N-methyl-2-((5-(piperazin-1-yl)pyridin-2-yl)amino)-7H-pyrrolo[2,3-d]pyrimidine-6-carboxamide is useful as reference Impurity standard. ![Ribociclib N-desmethyl Impurity; 7-cyclopentyl-N-methyl-2-((5-(piperazin-1-yl)pyridin-2-yl)amino)-7H-pyrrolo[2,3-d]pyrimidine-6-carboxamide](https://drjcrbio.com/wp-content/uploads/Ribociclib-N-desmethyl-impurity.png)
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Product Name : Ribociclib succinic acid Impurity; 4-[4-(6-{[7-cyclopentyl)-6-(N,N-dimethylcarabmoyl)-7H-pyrrolo[2,3-d]pyrimidin-2-yl]amino}pyridin-3-yl)piperazin-1-yl]-4-oxobutanoic acid; 4-(4-(6-((7-cyclopentyl-6-(dimethylcarbamoyl)-7H-pyrrolo[2,3-d]pyrimidin-2-yl)amino)pyridin-3-yl)piperazin-1-yl)-4-oxobutanoic acid
Code: JCRCB-16 CAS: NA Chemical Formula: C27H34N8O4 Molecular Weight: 534.62 Category: Ribociclib Reference Standards/API Drug Metabolites/EP Impurities/USP Impurities Literature: Application: Ribociclib succinic acid Impurity; 4-[4-(6-{[7-cyclopentyl)-6-(N,N-dimethylcarabmoyl)-7H-pyrrolo[2,3-d]pyrimidin-2-yl]amino}pyridin-3-yl)piperazin-1-yl]-4-oxobutanoic acid; 4-(4-(6-((7-cyclopentyl-6-(dimethylcarbamoyl)-7H-pyrrolo[2,3-d]pyrimidin-2-yl)amino)pyridin-3-yl)piperazin-1-yl)-4-oxobutanoic acid is useful as reference Impurity standard. ![Ribociclib succinic acid Impurity; 4-[4-(6-{[7-cyclopentyl)-6-(N,N-dimethylcarabmoyl)-7H-pyrrolo[2,3-d]pyrimidin-2-yl]amino}pyridin-3-yl)piperazin-1-yl]-4-oxobutanoic acid; 4-(4-(6-((7-cyclopentyl-6-(dimethylcarbamoyl)-7H-pyrrolo[2,3-d]pyrimidin-2-yl)amino)pyridin-3-yl)piperazin-1-yl)-4-oxobutanoic acid](https://drjcrbio.com/wp-content/uploads/Ribociclib-succinic-acid-Impurity-1.png)
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Product Name : Ribociclib alcohol Impurity; (7-cyclopentyl-2-((5-(piperazin-1-yl)pyridin-2-yl)amino)-7H-pyrrolo[2,3-d]pyrimidin-6-yl)methanol
Code: JCRCB-15 CAS: NA Chemical Formula: C21H27N7O Molecular Weight: 393.50 Category: Ribociclib Reference Standards/API Drug Metabolites/EP Impurities/USP Impurities Literature: Application: Ribociclib alcohol Impurity; (7-cyclopentyl-2-((5-(piperazin-1-yl)pyridin-2-yl)amino)-7H-pyrrolo[2,3-d]pyrimidin-6-yl)methanol is useful as reference Impurity standard. ![Ribociclib alcohol Impurity; (7-cyclopentyl-2-((5-(piperazin-1-yl)pyridin-2-yl)amino)-7H-pyrrolo[2,3-d]pyrimidin-6-yl)methanol](https://drjcrbio.com/wp-content/uploads/Ribociclib-alcohol-Impurity-7-cyclopentyl-2-5-piperazin-1-ylpyridin-2-ylamino-7H-pyrrolo23-dpyrimidin-6-ylmethanol.png)
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Product Name : Ribociclib acid Impurity ; 7-cyclopentyl-2-((5-(piperazin-1-yl)pyridin-2-yl)amino)-7H-pyrrolo[2,3-d]pyrimidine-6-carboxylic acid ; 2762182-61-4
Code: JCRCB-14 CAS: 2762182-61-4 Chemical Formula: C21H25N7O2 Molecular Weight: 407.48 Category: Ribociclib Reference Standards/API Drug Metabolites/EP Impurities/USP Impurities Literature: Application: Ribociclib acid Impurity ; 7-cyclopentyl-2-((5-(piperazin-1-yl)pyridin-2-yl)amino)-7H-pyrrolo[2,3-d]pyrimidine-6-carboxylic acid ; 2762182-61-4 is useful as reference Impurity standard. ![Ribociclib acid Impurity ; 7-cyclopentyl-2-((5-(piperazin-1-yl)pyridin-2-yl)amino)-7H-pyrrolo[2,3-d]pyrimidine-6-carboxylic acid ; 2762182-61-4](https://drjcrbio.com/wp-content/uploads/Ribociclib-acid-Impurity-7-cyclopentyl-2-5-piperazin-1-ylpyridin-2-ylamino-7H-pyrrolo23-dpyrimidine-6-carboxylic-acid-2762182-61-4.png)
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Product Name : tert-Butyl 4-(6-Amino-3-pyridyl)piperazine-1-carboxylate; 571188-59-5
Code: JCRCB-13 CAS:571188-59-5 Chemical Formula: C14H22N4O2 Molecular Weight: 278.36 Category: Ribociclib Reference Standards/API Drug Metabolites/EP Impurities/USP Impurities Literature: Application: tert-Butyl 4-(6-Amino-3-pyridyl)piperazine-1-carboxylate; 571188-59-5 is useful as reference Impurity standard. 
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Product Name : Ribociclib Succinate ; 7-Cyclopentyl-N,N-dimethyl-2-[(5-piperazin-1-ylpyridin-2-yl)amino]pyrrolo[2,3-d]pyrimidine-6-carboxamide butanedioic acid ; 1374639-75-4
Code: JCRCB-12 CAS: 1374639-75-4 Chemical Formula: C27H36N8O5 Molecular Weight: 552.63 Category: Ribociclib Reference Standards/API Drug Metabolites/EP Impurities/USP Impurities Literature: Application: Ribociclib Succinate ; 7-Cyclopentyl-N,N-dimethyl-2-[(5-piperazin-1-ylpyridin-2-yl)amino]pyrrolo[2,3-d]pyrimidine-6-carboxamide butanedioic acid ; 1374639-75-4 is useful as reference Impurity standard. ![Ribociclib Succinate ; 7-Cyclopentyl-N,N-dimethyl-2-[(5-piperazin-1-ylpyridin-2-yl)amino]pyrrolo[2,3-d]pyrimidine-6-carboxamide butanedioic acid ; 1374639-75-4](https://drjcrbio.com/wp-content/uploads/1374639-75-4.png)
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Product Name : 2-Chloro-7-cyclopentyl-7H-pyrrolo[2,3-d]pyrimidine-6-carbaldehyde ;1211443-55-8
Code: JCRCB-11 CAS:1211443-55-8 Chemical Formula: C12H12ClN3O Molecular Weight: 249.70 Category: Ribociclib Reference Standards/API Drug Metabolites/EP Impurities/USP Impurities Literature: Application: 2-Chloro-7-cyclopentyl-7H-pyrrolo[2,3-d]pyrimidine-6-carbaldehyde ;1211443-55-8 is useful as reference Impurity standard. ![2-Chloro-7-cyclopentyl-7H-pyrrolo[2,3-d]pyrimidine-6-carbaldehyde ;1211443-55-8](https://drjcrbio.com/wp-content/uploads/1211443-55-8.png)
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Product Name : 5-Bromo-2-chloro-N-cyclopentylpyrimidin-4-amine, 733039-20-8
Code: JCRCB-10 CAS:733039-20-8 Chemical Formula: C9H11BrClN3 Molecular Weight: 276.56 Category: Ribociclib Reference Standards/API Drug Metabolites/EP Impurities/USP Impurities Literature: Application: 5-Bromo-2-chloro-N-cyclopentylpyrimidin-4-amine, 733039-20-8 is useful as reference Impurity standard. 
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Product Name : Ribociclib N,N-DiDesmethyl Metabolite ; 7-Cyclopentyl-2-[(5-piperazin-1-ylpyridin-2-yl)amino]pyrrolo[2,3-d]pyrimidine-6-carboxamide
Code: JCRCB-09 CAS: NA Chemical Formula: C21H26N8O Molecular Weight: 406.48 Category: Ribociclib Reference Standards/API Drug Metabolites/EP Impurities/USP Impurities Literature: Application: Ribociclib N,N-DiDesmethyl Metabolite ; 7-Cyclopentyl-2-[(5-piperazin-1-ylpyridin-2-yl)amino]pyrrolo[2,3-d]pyrimidine-6-carboxamide is useful as reference Impurity standard. ![Ribociclib N,N-DiDesmethyl Metabolite ; 7-Cyclopentyl-2-[(5-piperazin-1-ylpyridin-2-yl)amino]pyrrolo[2,3-d]pyrimidine-6-carboxamide](https://drjcrbio.com/wp-content/uploads/7-Cyclopentyl-2-5-piperazin-1-ylpyridin-2-ylaminopyrrolo23-dpyrimidine-6-carboxamide-.png)
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Product Name : Ribociclib N-Desmethyl Metabolite ; 7-Cyclopentyl-N-methyl-2-[(5-piperazin-1-ylpyridin-2-yl)amino]pyrrolo[2,3-d]pyrimidine-6-carboxamide ; 1211441-59-6
Code: JCRCB-08 CAS: 1211441-59-6 Chemical Formula: C22H28N8O Molecular Weight: 420.51 Category: Ribociclib Reference Standards/API Drug Metabolites/EP Impurities/USP Impurities Literature: Application: Ribociclib N-Desmethyl Metabolite ; 7-Cyclopentyl-N-methyl-2-[(5-piperazin-1-ylpyridin-2-yl)amino]pyrrolo[2,3-d]pyrimidine-6-carboxamide ; 1211441-59-6 is useful as reference Impurity standard. ![Ribociclib N-Desmethyl Metabolite ; 7-Cyclopentyl-N-methyl-2-[(5-piperazin-1-ylpyridin-2-yl)amino]pyrrolo[2,3-d]pyrimidine-6-carboxamide ; 1211441-59-6](https://drjcrbio.com/wp-content/uploads/CAS-1211441-59-6-.png)
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Product Name : Ribociclib Chloro Hydroxymethyl Impurity ; 2-Chloro-7-cyclopentyl-7H-pyrrolo[2,3-d]pyrimidine-6-methanol ; 1374639-77-6
Code: JCRCB-07 CAS: 1374639-77-6 Chemical Formula: C12H14ClN3O Molecular Weight: 251.71 Category: Ribociclib Reference Standards/API Drug Metabolites/EP Impurities/USP Impurities Literature: Application: Ribociclib Chloro Hydroxymethyl Impurity ; 2-Chloro-7-cyclopentyl-7H-pyrrolo[2,3-d]pyrimidine-6-methanol ; 1374639-77-6 is useful as reference Impurity standard. ![Ribociclib Chloro Hydroxymethyl Impurity ; 2-Chloro-7-cyclopentyl-7H-pyrrolo[2,3-d]pyrimidine-6-methanol ; 1374639-77-6](https://drjcrbio.com/wp-content/uploads/1374639-77-6.png)
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Product Name : Ribociclib (Base) ; 7-Cyclopentyl-N,N-dimethyl-2-[(5-piperazin-1-ylpyridin-2-yl)amino]pyrrolo[2,3-d]pyrimidine-6-carboxamide ; 1211441-98-3
Code: JCRCB-06 CAS: 1211441-98-3 Chemical Formula: C23H30N8O Molecular Weight: 434.54 Category: Ribociclib Reference Standards/API Drug Metabolites/EP Impurities/USP Impurities Literature: Application: Ribociclib (Base) ; 7-Cyclopentyl-N,N-dimethyl-2-[(5-piperazin-1-ylpyridin-2-yl)amino]pyrrolo[2,3-d]pyrimidine-6-carboxamide ; 1211441-98-3 is useful as reference Impurity standard. ![Ribociclib (Base) ; 7-Cyclopentyl-N,N-dimethyl-2-[(5-piperazin-1-ylpyridin-2-yl)amino]pyrrolo[2,3-d]pyrimidine-6-carboxamide ; 1211441-98-3](https://drjcrbio.com/wp-content/uploads/1211441-98-3.png)
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Product Name : 2-(4-(6-aminopyridin-3-yl)piperazin-1-yl)-7-cyclopentyl-N,N-dimethyl-7H-pyrrolo[2,3-d]pyrimidine-6-carboxamide
Code: JCRCB-05 CAS: NA Chemical Formula: C23H30N8O Molecular Weight: 434.55 Category: Ribociclib Reference Standards/API Drug Metabolites/EP Impurities/USP Impurities Literature: Application:2-(4-(6-aminopyridin-3-yl)piperazin-1-yl)-7-cyclopentyl-N,N-dimethyl-7H-pyrrolo[2,3-d]pyrimidine-6-carboxamide is useful as reference Impurity standard. ![2-(4-(6-aminopyridin-3-yl)piperazin-1-yl)-7-cyclopentyl-N,N-dimethyl-7H-pyrrolo[2,3-d]pyrimidine-6-carboxamide](https://drjcrbio.com/wp-content/uploads/2-4-6-aminopyridin-3-ylpiperazin-1-yl-7-cyclopentyl-NN-dimethyl-7H-pyrrolo23-dpyrimidine-6-carboxamide.jpg)
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Product Name : 2-chloro-7-cyclopentyl-N-methyl-7H-pyrrolo[2,3-d]pyrimidine-6-carboxamide; 1211444-14-2
Code: JCRCB-04 CAS: 1211444-14-2 Chemical Formula: C13H15ClN4O Molecular Weight: 278.74 Category: Ribociclib Reference Standards/API Drug Metabolites/EP Impurities/USP Impurities Literature: Application: 2-chloro-7-cyclopentyl-N-methyl-7H-pyrrolo[2,3-d]pyrimidine-6-carboxamide; 1211444-14-2 is useful as reference Impurity standard. ![2-chloro-7-cyclopentyl-N-methyl-7H-pyrrolo[2,3-d]pyrimidine-6-carboxamide; 1211444-14-2](https://drjcrbio.com/wp-content/uploads/2-chloro-7-cyclopentyl-N-methyl-7H-pyrrolo23-dpyrimidine-6-carboxamide.jpg)
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Product Name : 2-Chloro-7-cyclopentyl-7H-pyrrolo[2,3-d]pyrimidine-6-carboxylic acid; 1211443-58-1
Code: JCRCB-03 CAS: 1211443-58-1 Chemical Formula: C12H12ClN3O2 Molecular Weight: 265.70 Category: Ribociclib Reference Standards/API Drug Metabolites/EP Impurities/USP Impurities Literature: Application: 2-Chloro-7-cyclopentyl-7H-pyrrolo[2,3-d]pyrimidine-6-carboxylic acid; 1211443-58-1 is useful as reference Impurity standard. ![2-Chloro-7-cyclopentyl-7H-pyrrolo[2,3-d]pyrimidine-6-carboxylic acid; 1211443-58-1](https://drjcrbio.com/wp-content/uploads/2-Chloro-7-cyclopentyl-7H-pyrrolo23-dpyrimidine-6-carboxylic-acid.jpg)
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Product Name : Ribociclib Chloro Amide Impurity; 2-Chloro-7-cyclopentyl-N,N-dimethyl-7H-pyrrolo[2,3-d]pyrimidine-6-carboxamide ; 1211443-61-6
Code: JCRCB-02 CAS:1211443-61-6 Chemical Formula: C14H17ClN4O Molecular Weight: 292.76 Category: Ribociclib Reference Standards/API Drug Metabolites/EP Impurities/USP Impurities Literature: Application: Ribociclib Chloro Amide Impurity; 2-Chloro-7-cyclopentyl-N,N-dimethyl-7H-pyrrolo[2,3-d]pyrimidine-6-carboxamide ; 1211443-61-6 is useful as reference Impurity standard. ![Ribociclib Chloro Amide Impurity; 2-Chloro-7-cyclopentyl-N,N-dimethyl-7H-pyrrolo[2,3-d]pyrimidine-6-carboxamide ; 1211443-61-6](https://drjcrbio.com/wp-content/uploads/Ribociclib-Chloro-Amide-Impurity-2-Chloro-7-cyclopentyl-NN-dimethyl-7H-pyrrolo23-dpyrimidine-6-carboxamide-1211443-61-6.jpg)
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Product Name : 2,5-dichloro-7-cyclopentyl-N, N-dimethyl-7H-pyrrolo[2,3-d]pyrimidine-6-carboxamide; 2577288-43-6
Code: JCRCB-01 CAS: 2577288-43-6 Chemical Formula: C14H16Cl2N4O Molecular Weight: 327.21 Category: Ribociclib Reference Standards/API Drug Metabolites/EP Impurities/USP Impurities Literature: Application: 2,5-dichloro-7-cyclopentyl-N, N-dimethyl-7H-pyrrolo[2,3-d]pyrimidine-6-carboxamide; 2577288-43-6 is useful as reference Impurity standard. ![2,5-dichloro-7-cyclopentyl-N, N-dimethyl-7H-pyrrolo[2,3-d]pyrimidine-6-carboxamide; 2577288-43-6](https://drjcrbio.com/wp-content/uploads/25-dichloro-7-cyclopentyl-N-N-dimethyl-7H-pyrrolo23-dpyrimidine-6-carboxamide.jpg)
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Product Name : Ribociclib Nitroso Impurity 1 ;7-cyclopentyl-N,N-dimethyl-2-((5-(4-nitrosopiperazin-1-yl)pyridin-2-yl)amino)-7H-pyrrolo[2,3-d]pyrimidine-6-carboxamide
Code: JCNTS-N113 CAS: NA Chemical Formula:C23H29N9O2 Molecular Weight:463.55 Category: Reference Standards/API Drug Metabolites/EP Impurities/USP Impurities Literature: Application: Ribociclib Nitroso Impurity 1 ;7-cyclopentyl-N,N-dimethyl-2-((5-(4-nitrosopiperazin-1-yl)pyridin-2-yl)amino)-7H-pyrrolo[2,3-d]pyrimidine-6-carboxamide is useful as reference Impurity standard. ![Ribociclib Nitroso Impurity 1 ;7-cyclopentyl-N,N-dimethyl-2-((5-(4-nitrosopiperazin-1-yl)pyridin-2-yl)amino)-7H-pyrrolo[2,3-d]pyrimidine-6-carboxamide](https://drjcrbio.com/wp-content/uploads/Ribociclib-Nitroso-Impurity-1-1.png)
