Palbociclib

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Palbociclib  API Reference standards and its EP Impurities, USP Impurities, non pharmacopeial Impurities, listed below & also offered custom synthesis for unknown Impurities. If require any contact info@drjcrbio.com, sales@drjcrbio.com

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    Product Name : Pazopanib impurity-20/1072836-76-0

    Code: JCPAZ-09
    CAS: 1072836-76-0
    Chemical Formula:C14H17N3O4S2
    Molecular Weight:355.4
    Category: Reference Standards/API Drug Metabolites/EP Impurities/USP Impurities
    Literature:
    Application: Pazopanib impurity-20/1072836-76-0 is useful as reference Impurity standard.
    Pazopanib impurity-20/1072836-76-0
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    Product Name : 5-bromo-2-nitropyridin-1-oxide ;Pyridine, 5-bromo-2-nitro-, 1-Oxide; 5-Bromo-2-nitropyridine 1-Oxide |27412-69-7

    Code: JCPBC-14
    CAS: 27412-69-7
    Chemical Formula:C5H3BrN2O3
    Molecular Weight:218.99
    Category: Reference Standards/API Drug Metabolites/EP Impurities/USP Impurities
    Literature:
    Application:  5-bromo-2-nitropyridin-1-oxide ;Pyridine, 5-bromo-2-nitro-, 1-Oxide; 5-Bromo-2-nitropyridine 1-Oxide |27412-69-7 is useful as reference Impurity standard.
    5-bromo-2-nitropyridin-1-oxide ;Pyridine, 5-bromo-2-nitro-, 1-Oxide; 5-Bromo-2-nitropyridine 1-Oxide |27412-69-7
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    Product Name : Tert-butyl 4-(2-nitropyridin-3-yl)piperazine-1-carboxylate ;1,1-Dimethylethyl 4-(2-nitro-3-pyridinyl)-1-piperazinecarboxylate; 1-Piperazinecarboxylic acid, 4-(2-nitro-3-pyridinyl)-, 1,1-dimethylethyl ester|1779124-68-3

    Code: JCPBC-13
    CAS: 1779124-68-3
    Chemical Formula:C14H20N4O4
    Molecular Weight:308.34
    Category: Reference Standards/API Drug Metabolites/EP Impurities/USP Impurities
    Literature:
    Application:  Tert-butyl 4-(2-nitropyridin-3-yl)piperazine-1-carboxylate ;1,1-Dimethylethyl 4-(2-nitro-3-pyridinyl)-1-piperazinecarboxylate; 1-Piperazinecarboxylic acid, 4-(2-nitro-3-pyridinyl)-, 1,1-dimethylethyl ester|1779124-68-3 is useful as reference Impurity standard.
    Tert-butyl 4-(2-nitropyridin-3-yl)piperazine-1-carboxylate ;1,1-Dimethylethyl 4-(2-nitro-3-pyridinyl)-1-piperazinecarboxylate; 1-Piperazinecarboxylic acid, 4-(2-nitro-3-pyridinyl)-, 1,1-dimethylethyl ester|1779124-68-3
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    Product Name : 3,5-dibromo-2-nitropyridine | 610261-34-2

    Code: JCPBC-12
    CAS: 610261-34-2
    Chemical Formula:C5H2Br2N2O2
    Molecular Weight:281.89
    Category: Reference Standards/API Drug Metabolites/EP Impurities/USP Impurities
    Literature:
    Application:   3,5-dibromo-2-nitropyridine | 610261-34-2is useful as reference Impurity standard.
    3,5-dibromo-2-nitropyridine | 610261-34-2
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    Product Name : 1-(6-nitropyridin-3-yl)piperazine;1-(6-Nitro-3-pyridinyl)piperazine|775288-71-6

    Code: JCPBC-11
    CAS: 775288-71-6
    Chemical Formula:C9H12N4O2
    Molecular Weight:208.22
    Category: Reference Standards/API Drug Metabolites/EP Impurities/USP Impurities
    Literature:
    Application:  1-(6-nitropyridin-3-yl)piperazine;1-(6-Nitro-3-pyridinyl)piperazine|775288-71-6 is useful as reference Impurity standard.
    1-(6-nitropyridin-3-yl)piperazine;1-(6-Nitro-3-pyridinyl)piperazine|775288-71-6
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    Product Name : Palbociclib Succinic Acid

    Code: JCPBC-10
    CAS: 1974279-21-4
    Chemical Formula: C28H33N7O5
    Molecular Weight:547.62
    Category: Reference Standards/API Drug Metabolites/EP Impurities/USP Impurities
    Literature:
    Application: 4-(4-(6-((6-Acetyl-8-cyclopentyl-5-methyl-7-oxo-7,8-dihydropyrido[2,3-d]pyrimidin-2-yl)amino)pyridin-3-yl)piperazin-1-yl)-4-oxobutanoic acid;1974279-21-4 is useful as reference Impurity standard
    Palbociclib Succinic Acid
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    Product Name : Palbociclib N-oxide;2174002-29-8

    Code: JCPBC-09
    CAS: 2174002-29-8
    Chemical Formula: C24H29N7O3
    Molecular Weight: 463.53
    Category: Reference Standards/API Drug Metabolites/EP Impurities/USP Impurities
    Literature:
    Application: Palbociclib N-oxide;2174002-29-8 is useful as reference Impurity standard
    Palbociclib N-oxide;2174002-29-8
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    Product Name : Palbociclib N-Formyl Impurity;2174002-16-3

    Code: JCPBC-08
    CAS: 2174002-16-3
    Chemical Formula: C25H29N7O3
    Molecular Weight: 475.54
    Category: Reference Standards/API Drug Metabolites/EP Impurities/USP Impurities
    Literature:
    Application:Palbociclib N-Formyl Impurity;4-(6-((6-acetyl-8-cyclopentyl-5-methyl-7-oxo-7,8-dihydropyrido[2,3-d]pyrimidin-2-yl)amino)pyridin-3-yl)piperazine-1-carbaldehyde;2174002-16-3 is useful as reference Impurity standard
    Palbociclib N-Formyl Impurity;2174002-16-3
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    Product Name : Palbociclib RC 11;6-Bromo-5-(bromomethyl)-2-chloro-8-cyclopentylpyrido[2,3-d]pyrimidin-7(8H)-one|2324831-15-2

    Code: JCPBC-07
    CAS: 2324831-15-2
    Chemical Formula:C13H12Br2ClN3O
    Molecular Weight:421.51
    Category: Reference Standards/API Drug Metabolites/EP Impurities/USP Impurities
    Literature:
    Application:  Palbociclib RC 11;6-Bromo-5-(bromomethyl)-2-chloro-8-cyclopentylpyrido[2,3-d]pyrimidin-7(8H)-one|2324831-15-2 is useful as reference Impurity standard.
    Palbociclib RC 11;6-Bromo-5-(bromomethyl)-2-chloro-8-cyclopentylpyrido[2,3-d]pyrimidin-7(8H)-one|2324831-15-2
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    Product Name : Palbociclib Impurity E; 6-bromo-8-cyclopentyl-5-methyl-2-[(5-piperazin-1-ylpyridin-2-yl)amino]pyrido[2,3-d]pyrimidin-7-one

    Code: JCPBC-06
    CAS: NA
    Chemical Formula: C22H26BrN7O
    Molecular Weight: 484.4
    Category: Reference Standards/API Drug Metabolites/EP Impurities/USP Impurities
    Literature:
    Application:Palbociclib Impurity E; 6-bromo-8-cyclopentyl-5-methyl-2-[(5-piperazin-1-ylpyridin-2-yl)amino]pyrido[2,3-d]pyrimidin-7-one is useful as reference Impurity standard
    Palbociclib Impurity E; 6-bromo-8-cyclopentyl-5-methyl-2-[(5-piperazin-1-ylpyridin-2-yl)amino]pyrido[2,3-d]pyrimidin-7-one
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    Product Name : Palbociclib Impurity D; 4-[6-(6-Acetyl-8-cyclopentyl-5-methyl-7-oxo-7,8-dihydro-pyrido[2,3-d]pyrimidin-2-ylamino)-pyridin-3-yl]-piperazine-1-carboxylic acid tert-butyl ester/1651214-74-2

    Code: JCPBC-05
    CAS: 1651214-74-2
    Chemical Formula: C29H37N7O4
    Molecular Weight: 547.6
    Category: Reference Standards/API Drug Metabolites/EP Impurities/USP Impurities
    Literature:
    Application:Palbociclib Impurity D; 4-[6-(6-Acetyl-8-cyclopentyl-5-methyl-7-oxo-7,8-dihydro-pyrido[2,3-d]pyrimidin-2-ylamino)-pyridin-3-yl]-piperazine-1-carboxylic acid tert-butyl ester  is useful as reference Impurity standard
    Palbociclib Impurity D; 4-[6-(6-Acetyl-8-cyclopentyl-5-methyl-7-oxo-7,8-dihydro-pyrido[2,3-d]pyrimidin-2-ylamino)-pyridin-3-yl]-piperazine-1-carboxylic acid tert-butyl ester/1651214-74-2
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    Product Name : Palbociclib Impurity C; 6-acetyl-8-cyclohexyl-5-methyl-2-[(5-piperazin-1-ylpyridin-2-yl)amino]pyrido[2,3-d]pyrimidin-7-one

    Code: JCPBC-04
    CAS: NA
    Chemical Formula:  C25H31N7O2
    Molecular Weight: 461.6
    Category: Reference Standards/API Drug Metabolites/EP Impurities/USP Impurities
    Literature:
    Application:Palbociclib Impurity C; 6-acetyl-8-cyclohexyl-5-methyl-2-[(5-piperazin-1-ylpyridin-2-yl)amino]pyrido[2,3-d]pyrimidin-7-one is useful as reference Impurity standard
    Palbociclib Impurity C; 6-acetyl-8-cyclohexyl-5-methyl-2-[(5-piperazin-1-ylpyridin-2-yl)amino]pyrido[2,3-d]pyrimidin-7-one
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    Product Name : Palbociclib Impurity B; 8-cyclophenyl-5-methyl-2-(5-(piperazin-1-yl)pyridin-2-ylamino)pyrido[2,3-d]pyrimidin-7(8H)-one

    Code: JCPBC-03
    CAS: NA
    Chemical Formula: C22H22N7O
    Molecular Weight: 405.5
    Category: Reference Standards/API Drug Metabolites/EP Impurities/USP Impurities
    Literature:
    Application:Palbociclib Impurity B; 8-cyclophenyl-5-methyl-2-(5-(piperazin-1-yl)pyridin-2-ylamino)pyrido[2,3-d]pyrimidin-7(8H)-one  is useful as reference Impurity standard
    Palbociclib Impurity B; 8-cyclophenyl-5-methyl-2-(5-(piperazin-1-yl)pyridin-2-ylamino)pyrido[2,3-d]pyrimidin-7(8H)-one
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    Product Name : Palbociclib Impurity A;5-(piperazin-1-yl)pyridin-2-amine

    Code: JCPBC-02
    CAS: NA
    Chemical Formula: C9H14N4
    Molecular Weight: 178.2
    Category: Reference Standards/API Drug Metabolites/EP Impurities/USP Impurities
    Literature:
    Application:Palbociclib Impurity A;5-(piperazin-1-yl)pyridin-2-amine  is useful as reference Impurity standard
    Palbociclib Impurity A;5-(piperazin-1-yl)pyridin-2-amine
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    Product Name : Palbociclib

    Code:   JCPBC-01
    CAS: NA
    Chemical Formula:  C24H29N7O2
    Molecular Weight: 447.54
    Category: Reference Standards/API Drug Metabolites/EP Impurities/USP Impurities
    Literature:
    Application: Palbociclib  is useful as reference Impurity standard
    Palbociclib
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