Nilotinib

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Nilotinib API Reference standards and its EP Impurities, USP Impurities, non pharmacopeial Impurities, listed below & also offered custom synthesis for unknown Impurities. If require any contact info@drjcrbio.com, sales@drjcrbio.com

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    Product Name : Nilotinib Impurity/943320-48-7

    Code: JCNNB-23
    CAS: 943320-48-7
    Chemical Formula:C10H8F3N3
    Molecular Weight: 227.19
    Category: Nilotinib Impurity ;Reference Standards/API Drug Metabolites/EP Impurities/USP Impurities
    Literature:
    Application:  3-(1H-imidazol1yl)-5(trifluoromethyl)aniline /943320-48-7 is useful as reference Impurity standard.
    Nilotinib Impurity/943320-48-7
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    Product Name : Nilotinib ethyl imidazole impurity; 3-(4-ethyl-1H-imidazol-1-yl)-5-(trifluoromethyl)aniline/2119583-27-4

    Code: JCNNB-22
    CAS: 2119583-27-4
    Chemical Formula: C12H12F3N3
    Molecular Weight: 255.24
    Category: Nilotinib Impurity ;Reference Standards/API Drug Metabolites/EP Impurities/USP Impurities
    Literature:
    Application:  Nilotinib ethyl imidazole impurity; 3-(4-ethyl-1H-imidazol-1-yl)-5-(trifluoromethyl)aniline/2119583-27-4 is useful as reference Impurity standard.
    Nilotinib ethyl imidazole impurity; 3-(4-ethyl-1H-imidazol-1-yl)-5-(trifluoromethyl)aniline/2119583-27-4
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    Product Name : 4-methyl-1-(3-nitro-5-(trifluoromethyl)phenyl)-1H-imidazole (Nitro imidazole)/916975-92-3

    Code: JCNNB-21
    CAS: 916975-92-3
    Chemical Formula: C11H8F3N3O2
    Molecular Weight: 271.20
    Category: Nilotinib Impurity ;Reference Standards/API Drug Metabolites/EP Impurities/USP Impurities
    Literature:
    Application:  4-Methyl-1-[3-nitro-5-(trifluoromethyl)phenyl]-1H-imidazole  is useful as reference Impurity standard.
    4-methyl-1-(3-nitro-5-(trifluoromethyl)phenyl)-1H-imidazole (Nitro imidazole)/916975-92-3
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    Product Name : (E)-3-(diMethylaMino)-1-(pyridin-2-yl)prop-2-en-1-one/123367-25-9

    Code: JCNNB-20
    CAS: 123367-25-9
    Chemical Formula: C10H12N2O
    Molecular Weight: 176.22
    Category: Nilotinib Impurity ;Reference Standards/API Drug Metabolites/EP Impurities/USP Impurities
    Literature:
    Application:  (E)-3-(diMethylaMino)-1-(pyridin-2-yl)prop-2-en-1-one/123367-25-9 is useful as reference Impurity standard.
    (E)-3-(diMethylaMino)-1-(pyridin-2-yl)prop-2-en-1-one/123367-25-9
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    Product Name : Ethyl 3-Carbamimidoylamino-4-methylbenzoate Nitrate | 641569-96-2

    Code: JCNNB-21
    CAS: 641569-96-2
    Chemical Formula: C11H15N3O2·HNO3
    Molecular Weight: 284.27
    Category: Reference Standards/ API Drug Metabolites/ EP Impurities/ USP Impurities
    Literature:
    Application:  Ethyl 3-Carbamimidoylamino-4-methylbenzoate Nitrate | 641569-96-2 is useful as reference Impurity standard
    Ethyl 3-Carbamimidoylamino-4-methylbenzoate Nitrate | 641569-96-2
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    Product Name : 3-(dimethyl amino)-1-(pyridin-2-yl)prop-2-en-1-one | 66521-54-8

    Code: JCNNB-20
    CAS: 66521-54-8
    Chemical Formula: C10H12N2O
    Molecular Weight: 176.22
    Category: Reference Standards/ API Drug Metabolites/ EP Impurities/ USP Impurities
    Literature:
    Application:  3-(dimethyl amino)-1-(pyridin-2-yl)prop-2-en-1-one | 66521-54-8 is useful as reference Impurity standard
     
    3-(dimethyl amino)-1-(pyridin-2-yl)prop-2-en-1-one | 66521-54-8
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    Product Name : Nilotinib Impurity D;3-(5-Chloro-4-(pyridin-3-yl)pyrimidin-2-ylamino)-4-methyl-N-(3-(4-methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)phenyl)benzamide |2469039-94-7

    Code: JCNNB-19
    CAS: 2469039-94-7
    Chemical Formula: C28H21ClF3N7O
    Molecular Weight: 563.97
    Category: Reference Standards/API Drug Metabolites/EP Impurities/USP Impurities
    Literature:
    Application:   Nilotinib Impurity D;3-(5-Chloro-4-(pyridin-3-yl)pyrimidin-2-ylamino)-4-methyl-N-(3-(4-methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)phenyl)benzamide |2469039-94-7is useful as reference Impurity standard.
    Nilotinib Impurity D;3-(5-Chloro-4-(pyridin-3-yl)pyrimidin-2-ylamino)-4-methyl-N-(3-(4-methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)phenyl)benzamide |2469039-94-7
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    Product Name : Nilotinib ;4-Methyl-N-[3-(4-methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)phenyl]-3-[[4-(3-pyridinyl)-2-pyrimidinyl]amino]-benzamide | 641571-10-0

    Code: JCNNB-18
    CAS: 641571-10-0
    Chemical Formula: C28H22F3N7O
    Molecular Weight: 529.52
    Category: Reference Standards/API Drug Metabolites/EP Impurities/USP Impurities
    Literature:
    Application: Nilotinib ;4-Methyl-N-[3-(4-methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)phenyl]-3-[[4-(3-pyridinyl)-2-pyrimidinyl]amino]-benzamide | 641571-10-0 is useful as reference Impurity standard.
    Nilotinib ;4-Methyl-N-[3-(4-methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)phenyl]-3-[[4-(3-pyridinyl)-2-pyrimidinyl]amino]-benzamide | 641571-10-0
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    Product Name : Nilotinib N-Oxide ;4-Methyl-N-[3-(4-methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)phenyl]-3-[[4-(3-pyridinyl-N-oxide)-2-pyrimidinyl]amino]benzamide | 1246817-85-5

    Code: JCNNB-17
    CAS: 1246817-85-5
    Chemical Formula: C28H22F3N7O2
    Molecular Weight: 545.52
    Category: Reference Standards/API Drug Metabolites/EP Impurities/USP Impurities
    Literature:
    Application:  Nilotinib N-Oxide ;4-Methyl-N-[3-(4-methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)phenyl]-3-[[4-(3-pyridinyl-N-oxide)-2-pyrimidinyl]amino]benzamide | 1246817-85-5 is useful as reference Impurity standard.
    Nilotinib N-Oxide ;4-Methyl-N-[3-(4-methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)phenyl]-3-[[4-(3-pyridinyl-N-oxide)-2-pyrimidinyl]amino]benzamide | 1246817-85-5
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    Product Name : Nilotinib USP RC C ; 3-Amino-4-methylbenzoic acid | 2458-12-0

    Code: JCNNB-16
    CAS: 2458-12-0
    Chemical Formula: C8H9NO2
    Molecular Weight: 151.16
    Category: Reference Standards/API Drug Metabolites/EP Impurities/USP Impurities
    Literature:
    Application: Nilotinib USP RC C ; 3-Amino-4-methylbenzoic acid | 2458-12-0 is useful as reference Impurity standard.
    Nilotinib USP RC C ; 3-Amino-4-methylbenzoic acid | 2458-12-0
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    Product Name : Nilotinib 2-Pyridinyl Impurity ;2-Amino-4-(2-pyridinyl)pyrimidine | 66521-65-1

    Code: JCNNB-15
    CAS: 66521-65-1
    Chemical Formula: C9H8N4
    Molecular Weight: 172.19
    Category: Reference Standards/API Drug Metabolites/EP Impurities/USP Impurities
    Literature:
    Application:  Nilotinib 2-Pyridinyl Impurity ;2-Amino-4-(2-pyridinyl)pyrimidine | 66521-65-1 is useful as reference Impurity standard.
    Nilotinib 2-Pyridinyl Impurity ;2-Amino-4-(2-pyridinyl)pyrimidine | 66521-65-1
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    Product Name : Nilotinib 3-Pyridinyl Impurity ;2-Amino-4-(3-pyridinyl)pyrimidine | 66521-66-2

    Code: JCNNB-14
    CAS: 66521-66-2
    Chemical Formula: C9H8N4
    Molecular Weight: 172.19
    Category: Reference Standards/API Drug Metabolites/EP Impurities/USP Impurities
    Literature:
    Application: Nilotinib 3-Pyridinyl Impurity ;2-Amino-4-(3-pyridinyl)pyrimidine | 66521-66-2 is useful as reference Impurity standard.
    Nilotinib 3-Pyridinyl Impurity ;2-Amino-4-(3-pyridinyl)pyrimidine | 66521-66-2
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    Product Name : Nilotinib Amide Impurity ; 4-Methyl-3-(4-(pyridin-3-yl)pyrimidin-2-ylamino)benzamide | 851137-91-2

    Code: JCNNB-13
    CAS: 851137-91-2
    Chemical Formula: C17H15N5O
    Molecular Weight: 305.33
    Category: Reference Standards/API Drug Metabolites/EP Impurities/USP Impurities
    Literature:
    Application: Nilotinib Amide Impurity ; 4-Methyl-3-(4-(pyridin-3-yl)pyrimidin-2-ylamino)benzamide | 851137-91-2 is useful as reference Impurity standard.
    Nilotinib Amide Impurity ; 4-Methyl-3-(4-(pyridin-3-yl)pyrimidin-2-ylamino)benzamide | 851137-91-2
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    Product Name : Nilotinib Amino Impurity ;3-(4-Methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)benzenamine | 641571-11-1

    Code: JCNNB-12
    CAS: 641571-11-1
    Chemical Formula: C11H10F3N3
    Molecular Weight: 241.21
    Category: Reference Standards/API Drug Metabolites/EP Impurities/USP Impurities
    Literature:
    Application: Nilotinib Amino Impurity ;3-(4-Methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)benzenamine | 641571-11-1 is useful as reference Impurity standard.
    Nilotinib Amino Impurity ;3-(4-Methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)benzenamine | 641571-11-1
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    Product Name : Nilotinib Bromo Impurity ;3-Bromo-5-(trifluoromethyl)benzenamine | 54962-75-3

    Code: JCNNB-11
    CAS: 54962-75-3
    Chemical Formula: C7H5BrF3N
    Molecular Weight: 240.02
    Category: Reference Standards/API Drug Metabolites/EP Impurities/USP Impurities
    Literature:
    Application: Nilotinib Bromo Impurity ;3-Bromo-5-(trifluoromethyl)benzenamine | 54962-75-3 is useful as reference Impurity standard.
    Nilotinib Bromo Impurity ;3-Bromo-5-(trifluoromethyl)benzenamine | 54962-75-3
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    Product Name : Nilotinib Carboxylic Acid Impurity ;4-Methyl-3-(4-(pyridin-3-yl)pyrimidin-2-ylamino)benzoic acid | 641569-94-0

    Code: JCNNB-10
    CAS: 641569-94-0
    Chemical Formula: C17H14N4O2
    Molecular Weight: 306.32
    Category: Reference Standards/API Drug Metabolites/EP Impurities/USP Impurities
    Literature:
    Application: Nilotinib Carboxylic Acid Impurity ;4-Methyl-3-(4-(pyridin-3-yl)pyrimidin-2-ylamino)benzoic acid | 641569-94-0 is useful as reference Impurity standard.
    Nilotinib Carboxylic Acid Impurity ;4-Methyl-3-(4-(pyridin-3-yl)pyrimidin-2-ylamino)benzoic acid | 641569-94-0
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    Product Name : Nilotinib Ethylimidazole Analog ;N-(3-(4-Ethyl-1H-imidazol-1-yl)-5-(trifluoromethyl)phenyl)-4-methyl-3-(4-(pyridin-3-yl)pyrimidin-2-ylamino)benzamide | 2119583-24-1

    Code: JCNNB-09
    CAS: 2119583-24-1
    Chemical Formula: C29H24F3N7O
    Molecular Weight: 543.54
    Category: Reference Standards/API Drug Metabolites/EP Impurities/USP Impurities
    Literature:
    Application: Nilotinib Ethylimidazole Analog ;N-(3-(4-Ethyl-1H-imidazol-1-yl)-5-(trifluoromethyl)phenyl)-4-methyl-3-(4-(pyridin-3-yl)pyrimidin-2-ylamino)benzamide | 2119583-24-1 is useful as reference Impurity standard.
    Nilotinib Ethylimidazole Analog ;N-(3-(4-Ethyl-1H-imidazol-1-yl)-5-(trifluoromethyl)phenyl)-4-methyl-3-(4-(pyridin-3-yl)pyrimidin-2-ylamino)benzamide | 2119583-24-1
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    Product Name : Nilotinib Formyl Impurity ; 4-Methyl-3-(4-(pyridin-3-yl)pyrimidin-2-ylamino)benzaldehyde

    Code: JCNNB-08
    CAS: NA
    Chemical Formula: C17H14N4O
    Molecular Weight: 290.32
    Category: Reference Standards/API Drug Metabolites/EP Impurities/USP Impurities
    Literature:
    Application: Nilotinib Formyl Impurity ; 4-Methyl-3-(4-(pyridin-3-yl)pyrimidin-2-ylamino)benzaldehyde is useful as reference Impurity standard.
    Nilotinib Formyl Impurity ; 4-Methyl-3-(4-(pyridin-3-yl)pyrimidin-2-ylamino)benzaldehyde
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    Product Name : Nilotinib Iodo Impurity ;3-Iodo-4-methyl-N-(3-(4-methyl-1H-imidazol-1-yl)-5-(trifluoromethyl) phenyl) benzamide | 926922-18-1

    Code: JCNNB-07
    CAS: 926922-18-1
    Chemical Formula:C19H15F3IN3O
    Molecular Weight: 485.24
    Category: Reference Standards/API Drug Metabolites/EP Impurities/USP Impurities
    Literature:
    Application: Nilotinib Iodo Impurity ;3-Iodo-4-methyl-N-(3-(4-methyl-1H-imidazol-1-yl)-5-(trifluoromethyl) phenyl) benzamide | 926922-18-1 is useful as reference Impurity standard.
    Nilotinib Iodo Impurity ;3-Iodo-4-methyl-N-(3-(4-methyl-1H-imidazol-1-yl)-5-(trifluoromethyl) phenyl) benzamide | 926922-18-1
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    Product Name : Methyl 3-Amino-4-methylbenzoate | 18595-18-1

    Code: JCNNB-06
    CAS: 18595-18-1
    Chemical Formula: C9H11NO2
    Molecular Weight: 165.19
    Category: Reference Standards/API Drug Metabolites/EP Impurities/USP Impurities
    Literature:
    Application: Methyl 3-Amino-4-methylbenzoate | 18595-18-1 is useful as reference Impurity standard.
    Methyl 3-Amino-4-methylbenzoate | 18595-18-1
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    Product Name : N-(3-(1H-imidazol-1-yl)-5-(trifluoromethyl)phenyl)-4-methyl-3-((4-(pyridin-3-yl)pyrimidin-2-yl)amino)benzamide

    Code: JCNNB-05
    CAS: 2119583-26-3
    Chemical Formula: C27H20F3N7O
    Molecular Weight: 515.50
    Category: Reference Standards/API Drug Metabolites/EP Impurities/USP Impurities
    Literature:
    Application: N-(3-(1H-imidazol-1-yl)-5-(trifluoromethyl)phenyl)-4-methyl-3-((4-(pyridin-3-yl)pyrimidin-2yl)amino)benzamide; 2119583-26-3 is useful as reference Impurity standard.
    N-(3-(1H-imidazol-1-yl)-5-(trifluoromethyl)phenyl)-4-methyl-3-((4-(pyridin-3-yl)pyrimidin-2-yl)amino)benzamide
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    Product Name : Methyl 4-methyl-3-((4-(pyridin-3-yl)pyrimidin-2-yl)amino)benzoate | 917392-54-2

    Code: JCNNB-04
    CAS: 917392-54-2
    Chemical Formula: C18H16N4O2
    Molecular Weight: 320.34
    Category: Reference Standards/API Drug Metabolites/EP Impurities/USP Impurities
    Literature:
    Application: Methyl 4-methyl-3-((4-(pyridin-3-yl)pyrimidin-2-yl)amino)benzoate | 917392-54-2 is useful as reference Impurity standard.
    Methyl 4-methyl-3-((4-(pyridin-3-yl)pyrimidin-2-yl)amino)benzoate | 917392-54-2
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    Product Name : Nilotinib positional Isomer; 4-methyl-N-(3-(5-methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)phenyl)-3-((4-(pyridin-3-yl)pyrimidin-2-yl)amino)benzamide | 641571-15-5

    Code: JCNNB-03
    CAS: 641571-15-5
    Chemical Formula: C28H22F3N7O
    Molecular Weight: 529.53
    Category: Reference Standards/API Drug Metabolites/EP Impurities/USP Impurities
    Literature:
    Application: Nilotinib positional Isomer; 4-methyl-N-(3-(5-methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)phenyl)-3-((4-(pyridin-3-yl)pyrimidin-2-yl)amino)benzamide;641571-15-5 is useful as reference Impurity standard.
    Nilotinib positional Isomer; 4-methyl-N-(3-(5-methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)phenyl)-3-((4-(pyridin-3-yl)pyrimidin-2-yl)amino)benzamide | 641571-15-5
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    Product Name : Nilotinib Impurity 1; 3-(4-Ethyl-1H-imidazol-1-yl)-5-(trifluoromethyl)aniline | 641571-06-4

    Code: JCNNB-02
    CAS: 641571-06-4
    Chemical Formula: C12H12F3N3
    Molecular Weight: 255.2
    Category: Reference Standards/API Drug Metabolites/EP Impurities/USP Impurities
    Literature:
    Application: Nilotinib Impurity 1; 3-(4-Ethyl-1H-imidazol-1-yl)-5-(trifluoromethyl)aniline | 641571-06-4 is useful as reference Impurity standard.
    Nilotinib Impurity 1; 3-(4-Ethyl-1H-imidazol-1-yl)-5-(trifluoromethyl)aniline | 641571-06-4
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    Product Name : Nilotinib Impurity 5; 3-(5-Methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)benzenamine | 641571-16-6

    Code: JCNNB-01
    CAS: 641571-16-6
    Chemical Formula: C11H10F3N3
    Molecular Weight: 241.2
    Category: Reference Standards/API Drug Metabolites/EP Impurities/USP Impurities
    Literature:
    Application: Nilotinib Impurity 5; 3-(5-Methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)benzenamine |641571-16-6 is useful as reference Impurity standard.
    Nilotinib Impurity 5; 3-(5-Methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)benzenamine | 641571-16-6
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