Nebivolol

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NebivololAPI Reference standards and its EP Impurities, USP Impurities, non pharmacopeial Impurities, listed below & also offered custom synthesis for unknown Impurities. If require any contact info@drjcrbio.com, sales@drjcrbio.com

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    Product Name : Nebivolol Des-Fluoro Impurity/99199-99-2

    Code: JCNBV-49
    CAS: 99199-99-2
    Chemical Formula: C11H12O2
    Molecular Weight:176.2
    Category: Nebivolol Reference Standards/ Nebivolol API Drug Metabolites/Nebivolol EP Impurities/Nebivolol USP Impurities
    Literature:
    Application: Nebivolol Des-Fluoro Impurity/99199-99-2 is useful as reference Impurity standard
    Nebivolol Des-Fluoro Impurity/99199-99-2
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    Product Name : (S,R,S,S)-Nebivolol; (S)-1-((S)-6-fluorochroman-2-yl)-2-(((R)-2-((S)-6-fluorochroman-2-yl)-2-hydroxyethyl)amino)ethan-1-ol; 119365-25-2

    Code: JCNBV-38
    CAS: 119365-25-2
    Chemical Formula: C₂₂H₂₅F₂NO₄
    Molecular Weight:405.44
    Category: Nebivolol Reference Standards/ Nebivolol API Drug Metabolites/Nebivolol EP Impurities/Nebivolol USP Impurities
    Literature:
    Application:  (S,R,S,S)-Nebivolol; (S)-1-((S)-6-fluorochroman-2-yl)-2-(((R)-2-((S)-6-fluorochroman-2-yl)-2-hydroxyethyl)amino)ethan-1-ol; 119365-25-2 is useful as reference Impurity standard.
    (S,R,S,S)-Nebivolol; (S)-1-((S)-6-fluorochroman-2-yl)-2-(((R)-2-((S)-6-fluorochroman-2-yl)-2-hydroxyethyl)amino)ethan-1-ol; 119365-25-2
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    Product Name : (R,R,R,R)-Nebivolol; (1R | 1’R)-2 | 2′-azanediylbis(1-((R)-6-fluorochroman-2-yl)ethan-1-ol); 119365-29-6

    Code: JCNBV-37
    CAS: 119365-29-6
    Chemical Formula: C₂₂H₂₅F₂NO₄
    Molecular Weight:405.44
    Category: Nebivolol Reference Standards/ Nebivolol API Drug Metabolites/Nebivolol EP Impurities/Nebivolol USP Impurities
    Literature:
    Application:  (R,R,R,R)-Nebivolol; (1R | 1'R)-2 | 2'-azanediylbis(1-((R)-6-fluorochroman-2-yl)ethan-1-ol); 119365-29-6 is useful as reference Impurity standard.
    (R,R,R,R)-Nebivolol; (1R | 1'R)-2 | 2'-azanediylbis(1-((R)-6-fluorochroman-2-yl)ethan-1-ol); 119365-29-6
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    Product Name : (R,S,R,R)-Nebivolol; (S)-1-((R)-6-fluorochroman-2-yl)-2-(((R)-2-((R)-6-fluorochroman-2-yl)-2-hydroxyethyl)amino)ethan-1-ol; 119365-26-3

    Code: JCNBV-36
    CAS: 119365-26-3
    Chemical Formula: C₂₂H₂₅F₂NO₄
    Molecular Weight:405.44
    Category: Nebivolol Reference Standards/ Nebivolol API Drug Metabolites/Nebivolol EP Impurities/Nebivolol USP Impurities
    Literature:
    Application:   (R,S,R,R)-Nebivolol; (S)-1-((R)-6-fluorochroman-2-yl)-2-(((R)-2-((R)-6-fluorochroman-2-yl)-2-hydroxyethyl)amino)ethan-1-ol; 119365-26-3 is useful as reference Impurity standard.
    (R,S,R,R)-Nebivolol; (S)-1-((R)-6-fluorochroman-2-yl)-2-(((R)-2-((R)-6-fluorochroman-2-yl)-2-hydroxyethyl)amino)ethan-1-ol; 119365-26-3
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    Product Name : (R,S,S,R)-Nebivolol; (1S | 1’S)-2 | 2′-azanediylbis(1-((R)-6-fluorochroman-2-yl)ethan-1-ol); 9365-30-9

    Code: JCNBV-35
    CAS: 9365-30-9
    Chemical Formula: C₂₂H₂₅F₂NO₄
    Molecular Weight:405.44
    Category: Nebivolol Reference Standards/ Nebivolol API Drug Metabolites/Nebivolol EP Impurities/Nebivolol USP Impurities
    Literature:
    Application:   (R,S,S,R)-Nebivolol; (1S | 1'S)-2 | 2'-azanediylbis(1-((R)-6-fluorochroman-2-yl)ethan-1-ol); 9365-30-9 is useful as reference Impurity standard.
    (R,S,S,R)-Nebivolol;  (1S | 1'S)-2 | 2'-azanediylbis(1-((R)-6-fluorochroman-2-yl)ethan-1-ol); 9365-30-9
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    Product Name : Nebivolol Impurity A ;(-)-Nebivolol; (αS,α’S,2R,2’S)-α,α’-[Iminobis(methylene)]bis[6-fluoro-3,4-dihydro-2H-1-benzopyran-2-methanol]; [2S-[2R*[R*[R*(S*)]]]]-α,α’-[Iminobis(methylene)]bis[6-fluoro-3,4-dihydro- 2H-1-benzopyran-2-methanol; Levonebivolol; R 67145; l-Nebivolol; | 118457-16-2

    Code: JCNBV-34
    CAS: 118457-16-2
    Chemical Formula: C₂₂H₂₅F₂NO₄
    Molecular Weight:405.44
    Category: Nebivolol Reference Standards/ Nebivolol API Drug Metabolites/Nebivolol EP Impurities/Nebivolol USP Impurities
    Literature:
    Application:   Nebivolol Impurity A ;(-)-Nebivolol; (αS,α’S,2R,2’S)-α,α’-[Iminobis(methylene)]bis[6-fluoro-3,4-dihydro-2H-1-benzopyran-2-methanol]; [2S-[2R*[R*[R*(S*)]]]]-α,α'-[Iminobis(methylene)]bis[6-fluoro-3,4-dihydro- 2H-1-benzopyran-2-methanol; Levonebivolol; R 67145; l-Nebivolol; | 118457-16-2 is useful as reference Impurity standard.
    Nebivolol Impurity A  ;(-)-Nebivolol; (αS,α’S,2R,2’S)-α,α’-[Iminobis(methylene)]bis[6-fluoro-3,4-dihydro-2H-1-benzopyran-2-methanol]; [2S-[2R*[R*[R*(S*)]]]]-α,α'-[Iminobis(methylene)]bis[6-fluoro-3,4-dihydro-2H-1-benzopyran-2-methanol; Levonebivolol; R 67145; l-Nebivolol;  |  118457-16-2
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    Product Name : Nebivolol Isomer B ;(S)-6-fluoro-2-((S)-oxiran-2-yl)chromane

    Code: JCNBV-33
    CAS: NA
    Chemical Formula:C11H11FO2
    Molecular Weight:194.21
    Category: Reference Standards/API Drug Metabolites/EP Impurities/USP Impurities
    Literature:
    Application:  Nebivolol Isomer B ;(S)-6-fluoro-2-((S)-oxiran-2-yl)chromane is useful as reference Impurity standard.
    Nebivolol Isomer B ;(S)-6-fluoro-2-((S)-oxiran-2-yl)chromane
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    Product Name : Nebivolol Isomer A ;(R)-6-fluoro-2-((R)-oxiran-2-yl)chromane

    Code: JCNBV-32
    CAS: NA
    Chemical Formula:C11H11FO2
    Molecular Weight:194.21
    Category: Reference Standards/API Drug Metabolites/EP Impurities/USP Impurities
    Literature:
    Application:  Nebivolol Isomer A ;(R)-6-fluoro-2-((R)-oxiran-2-yl)chromane is useful as reference Impurity standard.
    Nebivolol Isomer A ;(R)-6-fluoro-2-((R)-oxiran-2-yl)chromane
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    Product Name : SSRS = SRSS isomer; Nebivolol Impurity 28 (SS,RS); (S)-1-((S)-6-fluorochroman-2-yl)-2-(((R)-2-((S)-6-fluorochroman-2-yl)-2-hydroxyethyl)amino)ethan-1-ol |20299-27-0

    Code: JCNBV-31
    CAS: 20299-27-0
    Chemical Formula:C22H25F2NO4
    Molecular Weight:405.44
    Category: Reference Standards/API Drug Metabolites/EP Impurities/USP Impurities
    Literature:
    Application:  SSRS = SRSS isomer; Nebivolol Impurity 28 (SS,RS); (S)-1-((S)-6-fluorochroman-2-yl)-2-(((R)-2-((S)-6-fluorochroman-2-yl)-2-hydroxyethyl)amino)ethan-1-ol |20299-27-0 is useful as reference Impurity standard.
    SSRS = SRSS isomer; Nebivolol Impurity 28 (SS,RS); (S)-1-((S)-6-fluorochroman-2-yl)-2-(((R)-2-((S)-6-fluorochroman-2-yl)-2-hydroxyethyl)amino)ethan-1-ol  |20299-27-0
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    Product Name : Nebivolol Related Compound A ;1-(6-Fluorochroman-2-yl)-2-{[2-(6-fluorochroman-2-yl)-2-hydroxyethyl]amino}ethanol hydrochloride, mixture of isomers

    Code: JCNBV-30
    CAS: NA
    Chemical Formula:C22H25F2NO4 · HCl
    Molecular Weight:441.90
    Category: Reference Standards/API Drug Metabolites/EP Impurities/USP Impurities
    Literature:
    Application:  Nebivolol Related Compound A ;1-(6-Fluorochroman-2-yl)-2-{[2-(6-fluorochroman-2-yl)-2-hydroxyethyl]amino}ethanol hydrochloride, mixture of isomers is useful as reference Impurity standard.
    Nebivolol Related Compound A ;1-(6-Fluorochroman-2-yl)-2-{[2-(6-fluorochroman-2-yl)-2-hydroxyethyl]amino}ethanol hydrochloride, mixture of isomers
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    Product Name : Nebivolol Hydrochloride EP Impurity D ; (1RS)-1-[(2RS)-6-fluoro-3,4-dihydro-2H-1-benzopyran-2-yl]-2-[[(2SR)-2-[(2RS)-6-fluoro-3,4- dihydro-2H-1-benzopyran-2-yl]-2-hydroxyethyl]amino]ethan-1-ol

    Code: JCNBV-29
    CAS: NA
    Chemical Formula:C22H25F2NO4
    Molecular Weight: 405.44
    Category: Reference Standards/API Drug Metabolites/EP Impurities/USP Impurities
    Literature:
    Application:  Nebivolol Hydrochloride EP Impurity D ; (1RS)-1-[(2RS)-6-fluoro-3,4-dihydro-2H-1-benzopyran-2-yl]-2-[[(2SR)-2-[(2RS)-6-fluoro-3,4- dihydro-2H-1-benzopyran-2-yl]-2-hydroxyethyl]amino]ethan-1-ol is useful as reference Impurity standard.
    Nebivolol Hydrochloride EP Impurity D ; (1RS)-1-[(2RS)-6-fluoro-3,4-dihydro-2H-1-benzopyran-2-yl]-2-[[(2SR)-2-[(2RS)-6-fluoro-3,4- dihydro-2H-1-benzopyran-2-yl]-2-hydroxyethyl]amino]ethan-1-ol
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    Product Name : N-Nitroso-Nebivolol N,N-bis(2-(6-Flu;orochroman-2-yl)-2-hydroxyethyl)nitrous amide|1391051-68-5

    Code: JCNBV-28
    CAS: 1391051-68-5
    Chemical Formula: C22H24F2N2O5
    Molecular Weight: 434.4
    Category: Reference Standards/API Drug Metabolites/EP Impurities/USP Impurities
    Literature:
    Application: N-Nitroso-Nebivolol N,N-bis(2-(6-Flu;orochroman-2-yl)-2-hydroxyethyl)nitrous amide|1391051-68-5  is useful as reference Impurity standard.
    N-Nitroso-Nebivolol N,N-bis(2-(6-Flu;orochroman-2-yl)-2-hydroxyethyl)nitrous amide|1391051-68-5
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    Product Name : Nebivolol EP Impurity D ; (1RS)-1-[(2RS)-6-fluoro-3,4-dihydro-2H-1-benzopyran-2-yl]-2-[[(2SR)-2-[(2SR)-6-fluoro-3,4-dihydro-2H-1-benzopyran-2-yl]-2- hydroxyethyl]amino]ethan-1-ol

    Code: JCNBV-27
    CAS: NA
    Chemical Formula: C22H25F2NO4
    Molecular Weight: 405.44
    Category: Reference Standards/API Drug Metabolites/EP Impurities/USP Impurities
    Literature:
    Application: Nebivolol EP Impurity D ; (1RS)-1-[(2RS)-6-fluoro-3,4-dihydro-2H-1-benzopyran-2-yl]-2-[[(2SR)-2-[(2SR)-6-fluoro-3,4-dihydro-2H-1-benzopyran-2-yl]-2- hydroxyethyl]amino]ethan-1-ol  is useful as reference Impurity standard.
    Nebivolol EP Impurity D ; (1RS)-1-[(2RS)-6-fluoro-3,4-dihydro-2H-1-benzopyran-2-yl]-2-[[(2SR)-2-[(2SR)-6-fluoro-3,4-dihydro-2H-1-benzopyran-2-yl]-2- hydroxyethyl]amino]ethan-1-ol
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    Product Name : Nebivolol Hydrochloride A-Spot; (+/-)[1S*(S*)]-6-fluoro-3,4-dihydro-2-oxiranyl-2H-1-benzopyran”

    Code: JCNBV-26
    CAS: NA
    Chemical Formula: C11H11FO2
    Molecular Weight: 194.21
    Category: Reference Standards/API Drug Metabolites/EP Impurities/USP Impurities
    Literature:
    Application: Nebivolol Hydrochloride A-Spot ;(+/-)[1S*(S*)]-6-fluoro-3,4-dihydro-2-oxiranyl-2H-1-benzopyranis useful as reference Impurity standard.
    Nebivolol Hydrochloride A-Spot; (+/-)[1S*(S*)]-6-fluoro-3,4-dihydro-2-oxiranyl-2H-1-benzopyran
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    Product Name : Nebivolol Impurity B (SR,SS) ; [2S-[2R[R[S(R)]]]]-α,α’-[Iminobis(methylene)]bis[6-fluoro-3,4-dihydro-2H-1-benzopyran-2-methanol | 119365-25-2

    Code: JCNBV-25
    CAS: 119365-25-2
    Chemical Formula: C22H25F2NO4
    Molecular Weight: 441.90
    Category: Reference Standards/API Drug Metabolites/EP Impurities/USP Impurities
    Literature:
    Application: Nebivolol Impurity B (SR,SS) ; [2S-[2R[R[S(R)]]]]-α,α'-[Iminobis(methylene)]bis[6-fluoro-3,4-dihydro-2H-1-benzopyran-2-methanol | 119365-25-2  is useful as reference Impurity standard.
    Nebivolol Impurity B (SR,SS) ; [2S-[2R[R[S(R)]]]]-α,α'-[Iminobis(methylene)]bis[6-fluoro-3,4-dihydro-2H-1-benzopyran-2-methanol   | 119365-25-2
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    Product Name : Nebivolol Isomer (S,R,S,S) Synonym: (2S,αR,αS,2S)-α,α-[Iminobis(methylene)]bis[6-fluoro-3,4-dihydro-2H-1-benzopyran-2-methanol]

    Code: JCNBV-24
    CAS: NA
    Chemical Formula: 
    Molecular Weight:
    Category: Reference Standards/API Drug Metabolites/EP Impurities/USP Impurities
    Literature:
    Application: Nebivolol Isomer (S,R,S,S) Synonym: (2S,αR,αS,2S)-α,α-[Iminobis(methylene)]bis[6-fluoro-3,4-dihydro-2H-1-benzopyran-2-methanol]  ; is useful as reference Impurity standard.
    Nebivolol Isomer (S,R,S,S) Synonym: (2S,αR,αS,2S)-α,α-[Iminobis(methylene)]bis[6-fluoro-3,4-dihydro-2H-1-benzopyran-2-methanol]
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    Product Name : Nebivolol Isomer (R,S,R,R) Synonym: (2R,αS,αR,2R)-α,α-[Iminobis(methylene)]bis[6-fluoro-3,4-dihydro-2H-1-benzopyran-2-methanol] ;

    Code: JCNBV-23
    CAS: NA
    Chemical Formula: 
    Molecular Weight:
    Category: Reference Standards/API Drug Metabolites/EP Impurities/USP Impurities
    Literature:
    Application: Nebivolol Isomer (R,S,R,R) Synonym: (2R,αS,αR,2R)-α,α-[Iminobis(methylene)]bis[6-fluoro-3,4-dihydro-2H-1-benzopyran-2-methanol] ;is useful as reference Impurity standard.
    Nebivolol Isomer (R,S,R,R) Synonym: (2R,αS,αR,2R)-α,α-[Iminobis(methylene)]bis[6-fluoro-3,4-dihydro-2H-1-benzopyran-2-methanol] ;
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    Product Name : Nebivolol Isomer (SRSR+RSRS); (1R,1’R)-2,2′-azanediylbis(1-((R)-6-fluorochroman-2-yl)ethan-1-ol) compound with (R)-1-((R)-6-fluorochroman-2-yl)-2-(((S)-2-((S)-6-fluorochroman-2-yl)-2-hydroxyethyl)amino)ethan-1-ol

    Code: JCNBV-22
    CAS: NA
    Chemical Formula: C22H25F2NO4
    Molecular Weight: 405.44
    Category: Reference Standards/API Drug Metabolites/EP Impurities/USP Impurities
    Literature:
    Application:Nebivolol Isomer (SRSR+RSRS); (2S,αR,αS,2R)-α,α-[Iminobis(methylene)]bis[6-fluoro-3,4-dihydro-2H-1-benzopyran-2-methanol];(2R,αS,αR,2S)-α,α-[Iminobis(methylene)]bis[6-fluoro-3,4-dihydro-2H-1-benzopyran-2-methanol];is useful as reference Impurity standard.
    Nebivolol Isomer (SRSR+RSRS); (1R,1'R)-2,2'-azanediylbis(1-((R)-6-fluorochroman-2-yl)ethan-1-ol) compound with (R)-1-((R)-6-fluorochroman-2-yl)-2-(((S)-2-((S)-6-fluorochroman-2-yl)-2-hydroxyethyl)amino)ethan-1-ol
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    Product Name : Nebivolol Isomer (RSSS+SRRS) ;(2R,αS,αS,2S)-α,α-[Iminobis(methylene)]bis[6-fluoro-3,4-dihydro-2H-1-benzopyran-2-methanol];(2S,αR,αR,2S)-α,α-[Iminobis(methylene)]bis[6-fluoro-3,4-dihydro-2H-1-benzopyran-2-methanol]

    Code: JCNBV-21
    CAS: NA
    Chemical Formula: 
    Molecular Weight: 
    Category: Reference Standards/API Drug Metabolites/EP Impurities/USP Impurities
    Literature:
    Application: Nebivolol Isomer (RSSS+SRRS) ;(2R,αS,αS,2S)-α,α-[Iminobis(methylene)]bis[6-fluoro-3,4-dihydro-2H-1-benzopyran-2-methanol];(2S,αR,αR,2S)-α,α-[Iminobis(methylene)]bis[6-fluoro-3,4-dihydro-2H-1-benzopyran-2-methanol]is useful as reference Impurity standard.
    Nebivolol Isomer (RSSS+SRRS) ;(2R,αS,αS,2S)-α,α-[Iminobis(methylene)]bis[6-fluoro-3,4-dihydro-2H-1-benzopyran-2-methanol];(2S,αR,αR,2S)-α,α-[Iminobis(methylene)]bis[6-fluoro-3,4-dihydro-2H-1-benzopyran-2-methanol]
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    Product Name : Nebivolol USP RC E ;Monodesfluoro Nebivolol HCl ; 1-(Chroman-2-yl)-2-((2-(6-fluorochroman-2-yl)-2-hydroxyethyl)amino)ethanol hydrochloride ;; 129101-34-4 (base)

    Code: JCNBV-20
    CAS: 129101-34-4 (base)
    Chemical Formula: C22H27ClFNO4
    Molecular Weight: 423.91
    Category: Reference Standards/API Drug Metabolites/EP Impurities/USP Impurities
    Literature:
    Application: Nebivolol USP RC E ;Monodesfluoro Nebivolol HCl ; 1-(Chroman-2-yl)-2-((2-(6-fluorochroman-2-yl)-2-hydroxyethyl)amino)ethanol hydrochloride ;; 129101-34-4 (base) ; is useful as reference Impurity standard.
    Nebivolol USP RC E ;Monodesfluoro Nebivolol HCl ;  1-(Chroman-2-yl)-2-((2-(6-fluorochroman-2-yl)-2-hydroxyethyl)amino)ethanol hydrochloride ;; 129101-34-4 (base)
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    Product Name : Nebivolol USP RC D ;Mixture of (R)-6-Fluoro-2-[(S)-oxiran-2-yl]chroman and its enantiomer ; (RS)-6-Fluoro-2-[(SR)-oxiran-2-yl]chroman ; 793669-26-8

    Code: JCNBV-19
    CAS: 793669-26-8
    Chemical Formula: C11H11FO2
    Molecular Weight: 194.20
    Category: Reference Standards/API Drug Metabolites/EP Impurities/USP Impurities
    Literature:
    Application: Nebivolol USP RC D ;Mixture of (R)-6-Fluoro-2-[(S)-oxiran-2-yl]chroman and its enantiomer ; (RS)-6-Fluoro-2-[(SR)-oxiran-2-yl]chroman ; 793669-26-8 ; is useful as reference Impurity standard.
    Nebivolol USP RC D ;Mixture of (R)-6-Fluoro-2-[(S)-oxiran-2-yl]chroman and its enantiomer ;  (RS)-6-Fluoro-2-[(SR)-oxiran-2-yl]chroman ; 793669-26-8
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    Product Name : Nebivolol USP RC D (SR)-Isomer ;(S)-6-Fluoro-2-[(R)-oxiran-2-yl]chroman

    Code: JCNBV-18
    CAS: NA
    Chemical Formula: C11H11FO2
    Molecular Weight: 194.20
    Category: Reference Standards/API Drug Metabolites/EP Impurities/USP Impurities
    Literature:
    Application: Nebivolol USP RC D (SR)-Isomer ;(S)-6-Fluoro-2-[(R)-oxiran-2-yl]chroman ; is useful as reference Impurity standard.
    Nebivolol USP RC D (SR)-Isomer ;(S)-6-Fluoro-2-[(R)-oxiran-2-yl]chroman
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    Product Name : Nebivolol USP RC D (RS)-Isomer ;(R)-6-Fluoro-2-[(S)-oxiran-2-yl]chroman ;

    Code: JCNBV-17
    CAS: NA
    Chemical Formula: C11H11FO2
    Molecular Weight: 194.20
    Category: Reference Standards/API Drug Metabolites/EP Impurities/USP Impurities
    Literature:
    Application: Nebivolol USP RC D (RS)-Isomer ;(R)-6-Fluoro-2-[(S)-oxiran-2-yl]chroman ;is useful as reference Impurity standard.
    Nebivolol USP RC D (RS)-Isomer ;(R)-6-Fluoro-2-[(S)-oxiran-2-yl]chroman ;
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    Product Name : Nebivolol USP RC C ;Mixture of (R)-6-Fluoro-2-[(R)-oxiran-2-yl]chroman and its enantiomer ; (RS)-6-Fluoro-2-[(RS)-oxiran-2-yl]chroman ;876514-31-7

    Code: JCNBV-16
    CAS: 876514-31-7
    Chemical Formula: C11H11FO2
    Molecular Weight: 194.20
    Category: Reference Standards/API Drug Metabolites/EP Impurities/USP Impurities
    Literature:
    Application: Nebivolol USP RC C ;Mixture of (R)-6-Fluoro-2-[(R)-oxiran-2-yl]chroman and its enantiomer ; (RS)-6-Fluoro-2-[(RS)-oxiran-2-yl]chroman ;876514-31-7 ;is useful as reference Impurity standard.
    Nebivolol USP RC C ;Mixture of (R)-6-Fluoro-2-[(R)-oxiran-2-yl]chroman and its enantiomer ;  (RS)-6-Fluoro-2-[(RS)-oxiran-2-yl]chroman ;876514-31-7
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    Product Name : Nebivolol USP RC C (SS)-Isomer ;(S)-6-Fluoro-2-[(S)-oxiran-2-yl]chroman ;

    Code: JCNBV-15
    CAS: NA
    Chemical Formula: C11H11FO2
    Molecular Weight: 194.20
    Category: Reference Standards/API Drug Metabolites/EP Impurities/USP Impurities
    Literature:
    Application:Nebivolol USP RC C (SS)-Isomer ;(S)-6-Fluoro-2-[(S)-oxiran-2-yl]chroman ;is useful as reference Impurity standard.
    Nebivolol USP RC C (SS)-Isomer ;(S)-6-Fluoro-2-[(S)-oxiran-2-yl]chroman ;
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    Product Name : Nebivolol USP RC C (RR)-Isomer ;(R)-6-Fluoro-2-[(R)-oxiran-2-yl]chroman ;Nebivolol USP RC C (RR)-Isomer ;

    Code: JCNBV-14
    CAS: NA
    Chemical Formula: C11H11FO2
    Molecular Weight: 194.20
    Category: Reference Standards/API Drug Metabolites/EP Impurities/USP Impurities
    Literature:
    Application: Nebivolol USP RC C (RR)-Isomer ;(R)-6-Fluoro-2-[(R)-oxiran-2-yl]chroman ;Nebivolol USP RC C (RR)-Isomer ;is useful as reference Impurity standard.
    Nebivolol USP RC C (RR)-Isomer ;(R)-6-Fluoro-2-[(R)-oxiran-2-yl]chroman ;Nebivolol USP RC C (RR)-Isomer ;
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    Product Name : Nebivolol N-Benzyl Impurity ;(αSR,αSR,2RS,2SR)-α,α-[[(Phenylmethyl)imino]bis(methylene)]bis[6-fluoro-3,4-dihydro-2H-1-benzopyran-2-methanol ;

    Code: JCNBV-13
    CAS: 1199945-26-0
    Chemical Formula: C29H31F2NO4
    Molecular Weight: 495.56
    Category: Reference Standards/API Drug Metabolites/EP Impurities/USP Impurities
    Literature:
    Application: Nebivolol N-Benzyl Impurity ;(αSR,αSR,2RS,2SR)-α,α-[[(Phenylmethyl)imino]bis(methylene)]bis[6-fluoro-3,4-dihydro-2H-1-benzopyran-2-methanol ;is useful as reference Impurity standard.
    Nebivolol N-Benzyl Impurity ;(αSR,αSR,2RS,2SR)-α,α-[[(Phenylmethyl)imino]bis(methylene)]bis[6-fluoro-3,4-dihydro-2H-1-benzopyran-2-methanol ;
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    Product Name : Nebivolol HCl ;α,α’-[Iminobis(methylene)]bis[6-fluoro-3,4-dihydro-2H-1-benzopyran-2-methanol] HCl ; 169293-50-9 ;

    Code: JCNBV-12
    CAS:  169293-50-9; 118457-14-0, 152520-56-4, 99200-09-6
    Chemical Formula: 
    Molecular Weight: 
    Category: Nebivolol Reference Standards/Nebivolol API Drug Metabolites/Nebivolol EP Impurities/Nebivolol USP Impurities
    Literature:
    Application: Nebivolol HCl ;α,α’-[Iminobis(methylene)]bis[6-fluoro-3,4-dihydro-2H-1-benzopyran-2-methanol] HCl ; 169293-50-9 ;is useful as reference Impurity standard.
    Nebivolol HCl ;α,α’-[Iminobis(methylene)]bis[6-fluoro-3,4-dihydro-2H-1-benzopyran-2-methanol] HCl ;   169293-50-9 ;
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    Product Name : Nebivolol Didesfluoro Impurity ;1-(Chroman-2-yl)-2-((2-(chroman-2-yl)-2-hydroxyethyl)amino)ethanol ; 129101-33-3

    Code: JCNBV-11
    CAS:  129101-33-3
    Chemical Formula: C22H27NO4
    Molecular Weight: 369.45
    Category: Reference Standards/API Drug Metabolites/EP Impurities/USP Impurities
    Literature:
    Application: Nebivolol Didesfluoro Impurity ;1-(Chroman-2-yl)-2-((2-(chroman-2-yl)-2-hydroxyethyl)amino)ethanol ; 129101-33-3is useful as reference Impurity standard.
    Nebivolol Didesfluoro Impurity ;1-(Chroman-2-yl)-2-((2-(chroman-2-yl)-2-hydroxyethyl)amino)ethanol ; 129101-33-3
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    Product Name : Nebivolol Desfluorochromane N-Benzyl Impurity ; (1SR,2RS)-2-(2-Benzylamino-1-hydroxyethyl)-6-fluorochromane;

    Code: JCNBV-10
    CAS: 129050-27-7
    Chemical Formula: C18H20FNO2
    Molecular Weight: 301.36
    Category: Reference Standards/API Drug Metabolites/EP Impurities/USP Impurities
    Literature:
    Application: Nebivolol Desfluorochromane N-Benzyl Impurity ; (1SR,2RS)-2-(2-Benzylamino-1-hydroxyethyl)-6-fluorochromane;is useful as reference Impurity standard.
    Nebivolol Desfluorochromane N-Benzyl Impurity ; (1SR,2RS)-2-(2-Benzylamino-1-hydroxyethyl)-6-fluorochromane;
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    Product Name : Nebivolol 4-Hydroxy Impurity (HCl) ;6-Fluoro-α-[[[2-(6-fluoro-3,4-dihydro-2H-1-benzopyran-2-yl)-2-hydroxyethyl] amino]methyl]-3,4-dihydro-4-hydroxy-2H-1-benzopyran-2-methanol hydrochloride

    Code: JCNBV-09
    CAS: 178383-76-1 (base)
    Chemical Formula: C22H26ClF2NO5
    Molecular Weight: 457.9
    Category: Reference Standards/API Drug Metabolites/EP Impurities/USP Impurities
    Literature:
    Application: Nebivolol 4-Hydroxy Impurity (HCl) ;6-Fluoro-α-[[[2-(6-fluoro-3,4-dihydro-2H-1-benzopyran-2-yl)-2-hydroxyethyl] amino]methyl]-3,4-dihydro-4-hydroxy-2H-1-benzopyran-2-methanol hydrochlorideis useful as reference Impurity standard.
    Nebivolol 4-Hydroxy Impurity (HCl) ;6-Fluoro-α-[[[2-(6-fluoro-3,4-dihydro-2H-1-benzopyran-2-yl)-2-hydroxyethyl] amino]methyl]-3,4-dihydro-4-hydroxy-2H-1-benzopyran-2-methanol hydrochloride
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    Product Name : Nebivolol (S,S,S,S)-Isomer ;(2S,αS,αS,2S)-α,α-[Iminobis(methylene)]bis[6-fluoro-3,4-dihydro-2H-1-benzopyran-2-methanol] ;

    Code: JCNBV-08
    CAS: 119365-28-5 (base) ;
    Chemical Formula: C22H25F2NO4
    Molecular Weight: 405.44
    Category: Reference Standards/API Drug Metabolites/EP Impurities/USP Impurities
    Literature:
    Application: Nebivolol (S,S,S,S)-Isomer ;(2S,αS,αS,2S)-α,α-[Iminobis(methylene)]bis[6-fluoro-3,4-dihydro-2H-1-benzopyran-2-methanol] ;is useful as reference Impurity standard.
    Nebivolol (S,S,S,S)-Isomer ;(2S,αS,αS,2S)-α,α-[Iminobis(methylene)]bis[6-fluoro-3,4-dihydro-2H-1-benzopyran-2-methanol] ;
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    Product Name : Nebivolol (S,R,R,S)-Isomer ;(2S,αR,αR,2S)-α,α-[Iminobis(methylene)]bis[6-fluoro-3,4-dihydro-2H-1-benzopyran-2-methanol] ; 119365-23-0 ;

    Code: JCNBV-07
    CAS: 119365-23-0
    Chemical Formula: C22H25F2NO4
    Molecular Weight: 405.44
    Category: Reference Standards/API Drug Metabolites/EP Impurities/USP Impurities
    Literature:
    Application: Nebivolol (S,R,R,S)-Isomer ;(2S,αR,αR,2S)-α,α-[Iminobis(methylene)]bis[6-fluoro-3,4-dihydro-2H-1-benzopyran-2-methanol] ; 119365-23-0 ;is useful as reference Impurity standard.
    Nebivolol (S,R,R,S)-Isomer ;(2S,αR,αR,2S)-α,α-[Iminobis(methylene)]bis[6-fluoro-3,4-dihydro-2H-1-benzopyran-2-methanol] ; 119365-23-0 ;