Melphalan
17 Results Found
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Melphalan is a phenylalanine derivative of nitrogen mustard with antineoplastic activity. Melphalan alkylates DNA at the N7 position of guanine and induces DNA inter-strand cross-linkages, resulting in the inhibition of DNA and RNA synthesis and cytotoxicity against both dividing and non-dividing tumor cells (Ref: NCI Thesaurus (NCIt); pubchem)
Melphalan API Reference standards and its EP Impurities, USP Impurities, non pharmacopeial Impurities, listed below & also offered custom synthesis for unknown Impurities. If require any contact info@drjcrbio.com, sales@drjcrbio.com
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Product Name : Melphalan D-Isomer ;4-[Bis(2-chloroethyl)amino]-D-phenylalanine |13045-94-8
Code: JCMLP-17 CAS: 13045-94-8 Chemical Formula: C13H18Cl2N2O2 Molecular Weight: 305.20 Category: Reference Standards/API Drug Metabolites/EP Impurities/USP Impurities Literature: Application: Melphalan D-Isomer ;4-[Bis(2-chloroethyl)amino]-D-phenylalanine |13045-94-8 is useful as reference Impurity standard. ![Melphalan D-Isomer ;4-[Bis(2-chloroethyl)amino]-D-phenylalanine |13045-94-8](https://drjcrbio.com/wp-content/uploads/13045-94-8.png)
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Product Name : Melphalan ;4-[Bis(2-Chloroethyl)amino]-L-phenylalanine | 148-82-3
Code: JCMLP-01 CAS: 148-82-3 Chemical Formula:C13H18Cl2N2O2 Molecular Weight: 305.2 Category: Reference Standards/API Drug Metabolites/EP Impurities/USP Impurities Literature: Application: Melphalan ;4-[Bis(2-Chloroethyl)amino]-L-phenylalanine | 148-82-3 is useful as reference Impurity standard. ![Melphalan ;4-[Bis(2-Chloroethyl)amino]-L-phenylalanine | 148-82-3](https://drjcrbio.com/wp-content/uploads/R1-48.png)
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Product Name : Melphalan EP Impurity A ;Dihydroxy Melphatalan ;4-[bis(2-Hydroxyethyl)amino]-L-phenylalanine ;3-[p-[bis(2-Hydroxyethyl)amino]phenyl]alanine | 72143-20-5
Code: JCMLP-02 CAS: 72143-20-5 Chemical Formula: C13H20N2O4 Molecular Weight: 268.31 Category: Reference Standards/API Drug Metabolites/EP Impurities/USP Impurities Literature: Application: Melphalan EP Impurity A ;Dihydroxy Melphatalan ;4-[bis(2-Hydroxyethyl)amino]-L-phenylalanine ;3-[p-[bis(2-Hydroxyethyl)amino]phenyl]alanine | 72143-20-5 is useful as reference Impurity standard. ![Melphalan EP Impurity A ;Dihydroxy Melphatalan ;4-[bis(2-Hydroxyethyl)amino]-L-phenylalanine ;3-[p-[bis(2-Hydroxyethyl)amino]phenyl]alanine | 72143-20-5](https://drjcrbio.com/wp-content/uploads/E1-42.png)
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Product Name : Melphalan EP Impurity B ; 4-Morpholin-4-yl-L-phenylalanine ;(2S)-2-Amino-3-(4-morpholin-4-ylphenyl)propanoic Acid | 1270153-04-2
Code: JCMLP-03 CAS: 1270153-04-2 Chemical Formula: C13H18N2O3 Molecular Weight: 250.29 Category: Reference Standards/API Drug Metabolites/EP Impurities/USP Impurities Literature: Application: Melphalan EP Impurity B ; 4-Morpholin-4-yl-L-phenylalanine ;(2S)-2-Amino-3-(4-morpholin-4-ylphenyl)propanoic Acid | 1270153-04-2 is useful as reference Impurity standard. 
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Product Name : Melphalan EP Impurity C ; 4-[(2-Chloroethyl)amino]-L-phenylalanine dihydrochloride | 896715-19-8 (2 HCl)
Code: JCMLP-04 CAS: 896715-19-8 (2 HCl) Chemical Formula: C11H17Cl3N2O2 Molecular Weight: 315.62 Category: Reference Standards/API Drug Metabolites/EP Impurities/USP Impurities Literature: Application: Melphalan EP Impurity C ; 4-[(2-Chloroethyl)amino]-L-phenylalanine dihydrochloride | 896715-19-8 (2 HCl) is useful as reference Impurity standard. ![Melphalan EP Impurity C ; 4-[(2-Chloroethyl)amino]-L-phenylalanine dihydrochloride | 896715-19-8 (2 HCl)](https://drjcrbio.com/wp-content/uploads/E3-35.png)
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Product Name : Melphalan EP Impurity D ;Hydroxy Melphalan ;4-[(2-Chloroethyl)(2-hydroxyethyl)amino]-L-phenylalanine | 61733-01-5
Code: JCMLP-05 CAS: 61733-01-5 Chemical Formula: C13H19ClN2O3 Molecular Weight: 286.75 Category: Reference Standards/API Drug Metabolites/EP Impurities/USP Impurities Literature: Application: Melphalan EP Impurity D ;Hydroxy Melphalan ;4-[(2-Chloroethyl)(2-hydroxyethyl)amino]-L-phenylalanine | 61733-01-5 is useful as reference Impurity standard. ![Melphalan EP Impurity D ;Hydroxy Melphalan ;4-[(2-Chloroethyl)(2-hydroxyethyl)amino]-L-phenylalanine | 61733-01-5](https://drjcrbio.com/wp-content/uploads/E4-37.png)
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Product Name : Melphalan EP Impurity E ;4-[(2-Chloroethyl)(2-ethoxyethyl)amino]-L-phenylalanine
Code: JCMLP-06 CAS: NA Chemical Formula: C15H23ClN2O3 Molecular Weight: 314.81 Category: Reference Standards/API Drug Metabolites/EP Impurities/USP Impurities Literature: Application: Melphalan EP Impurity E ;4-[(2-Chloroethyl)(2-ethoxyethyl)amino]-L-phenylalanine is useful as reference Impurity standard. ![Melphalan EP Impurity E ;4-[(2-Chloroethyl)(2-ethoxyethyl)amino]-L-phenylalanine](https://drjcrbio.com/wp-content/uploads/E5-34.png)
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Product Name : Melphalan EP Impurity F ;3-Chloromelphalan HCl ; 4-[bis(2-Chloroethyl)amino]-3-chloro-L-phenylalanine hydrochloride
Code: JCMLP-07 CAS: NA Chemical Formula: C13H18Cl4N2O2 Molecular Weight: 376.11 Category: Reference Standards/API Drug Metabolites/EP Impurities/USP Impurities Literature: Application: Melphalan EP Impurity F ;3-Chloromelphalan HCl ; 4-[bis(2-Chloroethyl)amino]-3-chloro-L-phenylalanine hydrochloride is useful as reference Impurity standard. ![Melphalan EP Impurity F ;3-Chloromelphalan HCl ; 4-[bis(2-Chloroethyl)amino]-3-chloro-L-phenylalanine hydrochloride](https://drjcrbio.com/wp-content/uploads/E6-25.png)
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Product Name : Melphalan EP Impurity G ;Melphalan Dimer HCl ;4-[[2-[[4-[bis(2-Chloroethyl)amino]-L-phenylalanyl]oxy]ethyl](2-chloroethyl)amino]-L-phenylalanine hydrochloride
Code: JCMLP-08 CAS: NA Chemical Formula: C26H36Cl4N4O4 Molecular Weight: 610.4 Category: Reference Standards/API Drug Metabolites/EP Impurities/USP Impurities Literature: Application: Melphalan EP Impurity G ;Melphalan Dimer HCl ;4-[[2-[[4-[bis(2-Chloroethyl)amino]-L-phenylalanyl]oxy]ethyl](2-chloroethyl)amino]-L-phenylalanine hydrochloride is useful as reference Impurity standard. ![Melphalan EP Impurity G ;Melphalan Dimer HCl ;4-[[2-[[4-[bis(2-Chloroethyl)amino]-L-phenylalanyl]oxy]ethyl](2-chloroethyl)amino]-L-phenylalanine hydrochloride](https://drjcrbio.com/wp-content/uploads/E7-22.png)
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Product Name : Melphalan EP Impurity H ; Melphalan Methyl Ester HCl ;Methyl 4-[bis(2-Chloroethyl)amino]-L-phenylalaninate hydrochloride | 62978-52-3 (HCl);88457-23-2 (base) ;
Code: JCMLP-09 CAS: 62978-52-3 (HCl),88457-23-2 (base) ; Chemical Formula: C14H21Cl3N2O2 Molecular Weight: 355.69 Category: Reference Standards/API Drug Metabolites/EP Impurities/USP Impurities Literature: Application: Melphalan EP Impurity H ; Melphalan Methyl Ester HCl ;Methyl 4-[bis(2-Chloroethyl)amino]-L-phenylalaninate hydrochloride | 62978-52-3 (HCl);88457-23-2 (base) ; is useful as reference Impurity standard. ![Melphalan EP Impurity H ; Melphalan Methyl Ester HCl ;Methyl 4-[bis(2-Chloroethyl)amino]-L-phenylalaninate hydrochloride | 62978-52-3 (HCl);88457-23-2 (base) ;](https://drjcrbio.com/wp-content/uploads/E8-15.png)
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Product Name : Melphalan EP Impurity I ;Methoxy Dechloro Melphalan HCl ;4-[(2-Chloroethyl)(2-methoxyethyl)amino]-L-phenylalanine dihydrochloride
Code: JCMLP-10 CAS: NA Chemical Formula: C14H23Cl3N2O3 Molecular Weight: 373.7 Category: Reference Standards/API Drug Metabolites/EP Impurities/USP Impurities Literature: Application: Melphalan EP Impurity I ;Methoxy Dechloro Melphalan HCl ;4-[(2-Chloroethyl)(2-methoxyethyl)amino]-L-phenylalanine dihydrochloride is useful as reference Impurity standard. ![Melphalan EP Impurity I ;Methoxy Dechloro Melphalan HCl ;4-[(2-Chloroethyl)(2-methoxyethyl)amino]-L-phenylalanine dihydrochloride](https://drjcrbio.com/wp-content/uploads/E9-10.png)
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Product Name : Melphalan EP Impurity J ;2-Chloroethoxy Dechloro Melphalan ;4-[[2-(2-Chloroethoxy)ethyl](2-chloroethyl)amino]-L-phenylalanine
Code: JCMLP-11 CAS: NA Chemical Formula: C15H22Cl2N2O3 Molecular Weight: 349.25 Category: Reference Standards/API Drug Metabolites/EP Impurities/USP Impurities Literature: Application: Melphalan EP Impurity J ;2-Chloroethoxy Dechloro Melphalan ;4-[[2-(2-Chloroethoxy)ethyl](2-chloroethyl)amino]-L-phenylalanine is useful as reference Impurity standard. amino]-L-phenylalanine](https://drjcrbio.com/wp-content/uploads/E10-10.png)
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Product Name : Melphalan EP Impurity K ;Diethylamine HCl ; N-Ethylethanamine Hydrochloride | 109-89-7(base) ; 660-68-4 (HCl salt) ;
Code: JCMLP-12 CAS: 109-89-7 Chemical Formula: C4H12ClN Molecular Weight: 109.60(base) ; 660-68-4 (HCl salt) ; Category: Reference Standards/API Drug Metabolites/EP Impurities/USP Impurities Literature: Application: Melphalan EP Impurity K ;Diethylamine HCl ; N-Ethylethanamine Hydrochloride | 109-89-7(base) ; 660-68-4 (HCl salt) ; is useful as reference Impurity standard. 
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Product Name : Melphalan Ethyl Ester ; (S)-Ethyl 2-amino-3-(4-(bis(2-chloroethyl)amino)phenyl)propanoate hydrochloride | 112117-81-4 (HCl) ; 18067-07-7 (Base)
Code: JCMLP-13 CAS: 112117-81-4 (HCl) ; 18067-07-7 (Base) Chemical Formula: C15H23Cl3N2O2 Molecular Weight: 369.71 Category: Reference Standards/API Drug Metabolites/EP Impurities/USP Impurities Literature: Application: Melphalan Ethyl Ester ; (S)-Ethyl 2-amino-3-(4-(bis(2-chloroethyl)amino)phenyl)propanoate hydrochloride |112117-81-4 (HCl) ; 18067-07-7 (Base) is useful as reference Impurity standard. 
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Product Name : Melphalan HCl ;4-[Bis(2-Chloroethyl)amino]-L-phenylalanine HCl | 3223-07-2
Code: JCMLP-14 CAS: 3223-07-2 Chemical Formula: C13H19Cl3N2O2 Molecular Weight: 341.66 Category: Reference Standards/API Drug Metabolites/EP Impurities/USP Impurities Literature: Application: Melphalan HCl ;4-[Bis(2-Chloroethyl)amino]-L-phenylalanine HCl | 3223-07-2 is useful as reference Impurity standard. ![Melphalan HCl ;4-[Bis(2-Chloroethyl)amino]-L-phenylalanine HCl | 3223-07-2](https://drjcrbio.com/wp-content/uploads/N2-42.png)
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Product Name : Melphalan Isopropyl Ester ;(S)-Isopropyl 2-amino-3-(4-(bis(2-chloroethyl)amino)phenyl)propanoate dihydrochloride | 104874-57-9
Code: JCMLP-15 CAS: 104874-57-9 Chemical Formula: C16H26Cl4N2O2 Molecular Weight: 420.2 Category: Reference Standards/API Drug Metabolites/EP Impurities/USP Impurities Literature: Application: Melphalan Isopropyl Ester ;(S)-Isopropyl 2-amino-3-(4-(bis(2-chloroethyl)amino)phenyl)propanoate dihydrochloride | 104874-57-9 is useful as reference Impurity standard. 
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Product Name : Melphalan meta-Isomer ;Metamelfalan ; 3-[Bis(2-chloroethyl)amino]-L-phenylalanine | 1088-80-8
Code: JCMLP-16 CAS: 1088-80-8 Chemical Formula: C13H18Cl2N2O2 Molecular Weight: 305.2 Category: Reference Standards/API Drug Metabolites/EP Impurities/USP Impurities Literature: Application: Melphalan meta-Isomer ;Metamelfalan ; 3-[Bis(2-chloroethyl)amino]-L-phenylalanine | 1088-80-8 is useful as reference Impurity standard. ![Melphalan meta-Isomer ;Metamelfalan ; 3-[Bis(2-chloroethyl)amino]-L-phenylalanine | 1088-80-8](https://drjcrbio.com/wp-content/uploads/1088-80-8.png)
