Levothyroxine

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Levothyroxine API Reference standards and its EP Impurities, USP Impurities, non pharmacopeial Impurities, listed below & also offered custom synthesis for unknown Impurities. If require any contact info@drjcrbio.com, sales@drjcrbio.com

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    Product Name : Levothyroxine Acetamide Impurity ; T4-Acetamide (USP) ;2-(4-(4-Hydroxy-3,5-diiodophenoxy)-3,5-diiodophenyl)acetamide | 176258-88-1

    Code: JCLTX-24
    CAS: 176258-88-1
    Chemical Formula: C14H9I4NO3
    Molecular Weight: 746.84
    Category: Reference Standards/API Drug Metabolites/EP Impurities/USP Impurities
    Literature:
    Application: Levothyroxine Acetamide Impurity ; T4-Acetamide (USP) ;2-(4-(4-Hydroxy-3,5-diiodophenoxy)-3,5-diiodophenyl)acetamide | 176258-88-1  is useful as reference Impurity standard
    Levothyroxine Acetamide Impurity ; T4-Acetamide (USP) ;2-(4-(4-Hydroxy-3,5-diiodophenoxy)-3,5-diiodophenyl)acetamide  |  176258-88-1
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    Product Name : Levothyroxine beta-Hydroxy Impurity ;beta-Hydroxy T4 (USP) ; O-(4-Hydroxy-3,5-diiodophenyl)-3,5-diiodo-beta-hydroxy-L-tyrosine | 107849-54-7

    Code: JCLTX-23
    CAS:  107849-54-7
    Chemical Formula: C15H11I4NO5
    Molecular Weight: 792.87
    Category: Reference Standards/API Drug Metabolites/EP Impurities/USP Impurities
    Literature:
    Application: Levothyroxine beta-Hydroxy Impurity ;beta-Hydroxy T4 (USP) ; O-(4-Hydroxy-3,5-diiodophenyl)-3,5-diiodo-beta-hydroxy-L-tyrosine | 107849-54-7  is useful as reference Impurity standard
    Levothyroxine beta-Hydroxy Impurity ;beta-Hydroxy T4 (USP) ; O-(4-Hydroxy-3,5-diiodophenyl)-3,5-diiodo-beta-hydroxy-L-tyrosine  |  107849-54-7
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    Product Name : Levothyroxine D-Isomer ; (2R)-Amino-3-(4-(4-hydroxy-3,5-diiodophenoxy)-3,5-diiodophenyl) propanoic acid | 51-49-0

    Code: JCLTX-22
    CAS: 51-49-0
    Chemical Formula: C15H11I4NO4
    Molecular Weight: 776.87
    Category: Reference Standards/API Drug Metabolites/EP Impurities/USP Impurities
    Literature:
    Application: Levothyroxine D-Isomer ; (2R)-Amino-3-(4-(4-hydroxy-3,5-diiodophenoxy)-3,5-diiodophenyl) propanoic acid | 51-49-0 is useful as reference Impurity standard
    Levothyroxine D-Isomer ; (2R)-Amino-3-(4-(4-hydroxy-3,5-diiodophenoxy)-3,5-diiodophenyl) propanoic acid  |  51-49-0
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    Product Name : Levothyroxine EP Impurity A ;Liothyronine ; (2S)-2-Amino-3-[4-(4-hydroxy-3-iodophenoxy)-3,5-diiodophenyl]propanoic acid | 6893-02-3

    Code: JCLTX-21
    CAS: 6893-02-3
    Chemical Formula: C15H12I3NO4
    Molecular Weight: 650.97
    Category: Reference Standards/API Drug Metabolites/EP Impurities/USP Impurities
    Literature:
    Application: Levothyroxine EP Impurity A ;Liothyronine ; (2S)-2-Amino-3-[4-(4-hydroxy-3-iodophenoxy)-3,5-diiodophenyl]propanoic acid | 6893-02-3  is useful as reference Impurity standard
    Levothyroxine EP Impurity A ;Liothyronine ; (2S)-2-Amino-3-[4-(4-hydroxy-3-iodophenoxy)-3,5-diiodophenyl]propanoic acid  |  6893-02-3
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    Product Name : Levothyroxine EP Impurity B ;Levothyroxine Chloro Impurity ;3-Chloro Thyroxine ; (2S)-2-Amino-3-[4-(3-chloro-4-hydroxy-5-iodophenoxy)-3,5-diiodophenyl] propanoic acid

    Code: JCLTX-20
    CAS: NA
    Chemical Formula: C15H11ClI3NO4
    Molecular Weight: 685.42
    Category: Reference Standards/API Drug Metabolites/EP Impurities/USP Impurities
    Literature:
    Application: Levothyroxine EP Impurity B ;Levothyroxine Chloro Impurity ;3-Chloro Thyroxine ; (2S)-2-Amino-3-[4-(3-chloro-4-hydroxy-5-iodophenoxy)-3,5-diiodophenyl] propanoic acid is useful as reference Impurity standard
    Levothyroxine EP Impurity B ;Levothyroxine Chloro Impurity ;3-Chloro Thyroxine ; (2S)-2-Amino-3-[4-(3-chloro-4-hydroxy-5-iodophenoxy)-3,5-diiodophenyl] propanoic acid
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    Product Name : Levothyroxine EP Impurity C ;T3-Acetic Acid (USP) ;Triiodothyroacetic acid ;[4-(4-Hydroxy-3-iodophenoxy)-3,5-diiodophenyl]acetic acid | 51-24-1

    Code: JCLTX-19
    CAS: 51-24-1
    Chemical Formula: C14H9I3O4
    Molecular Weight: 621.93
    Category: Reference Standards/API Drug Metabolites/EP Impurities/USP Impurities
    Literature:
    Application: Levothyroxine EP Impurity C ;T3-Acetic Acid (USP) ;Triiodothyroacetic acid ;[4-(4-Hydroxy-3-iodophenoxy)-3,5-diiodophenyl]acetic acid | 51-24-1  is useful as reference Impurity standard
    Levothyroxine EP Impurity C ;T3-Acetic Acid (USP) ;Triiodothyroacetic acid ;[4-(4-Hydroxy-3-iodophenoxy)-3,5-diiodophenyl]acetic acid  |  51-24-1
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    Product Name : Levothyroxine EP Impurity D ;T4-Acetic Acid (USP) ;Tetraiodothyroacetic acid ; [4-(4-Hydroxy-3,5-diiodophenoxy)-3,5-diiodophenyl]acetic acid | 67-30-1

    Code: JCLTX-18
    CAS:  67-30-1
    Chemical Formula: C14H8I4O4
    Molecular Weight: 747.83
    Category: Reference Standards/API Drug Metabolites/EP Impurities/USP Impurities
    Literature:
    Application: Levothyroxine EP Impurity D ;T4-Acetic Acid (USP) ;Tetraiodothyroacetic acid ; [4-(4-Hydroxy-3,5-diiodophenoxy)-3,5-diiodophenyl]acetic acid | 67-30-1  is useful as reference Impurity standard
    Levothyroxine EP Impurity D ;T4-Acetic Acid (USP) ;Tetraiodothyroacetic acid ; [4-(4-Hydroxy-3,5-diiodophenoxy)-3,5-diiodophenyl]acetic acid   |  67-30-1
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    Product Name : Levothyroxine EP Impurity E ;Diiodothyronine ; (2S)-2-Amino-3-[4-(4-hydroxyphenoxy)-3,5-diiodophenyl]-propanoic acid | 1041-01-6

    Code: JCLTX-17
    CAS:  1041-01-6
    Chemical Formula: C15H13I2NO4
    Molecular Weight: 525.08
    Category: Reference Standards/API Drug Metabolites/EP Impurities/USP Impurities
    Literature:
    Application:   Levothyroxine EP Impurity E ;Diiodothyronine ; (2S)-2-Amino-3-[4-(4-hydroxyphenoxy)-3,5-diiodophenyl]-propanoic acid | 1041-01-6  is useful as reference Impurity standard
    Levothyroxine EP Impurity E ;Diiodothyronine ; (2S)-2-Amino-3-[4-(4-hydroxyphenoxy)-3,5-diiodophenyl]-propanoic acid  |  1041-01-6
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    Product Name : Levothyroxine EP Impurity F ; Levothyroxine T6 Impurity (USP) ;O-(4-Hydroxy-3,5-diiodophenyl)thyroxine ;(2S)-2-Amino-3-[4-[4-(4-hydroxy-3,5-diiodophenoxy)-3,5-diiodophenoxy]-3,5-diiodophenyl]propanoic acid | 911661-90-0

    Code: JCLTX-16
    CAS:  911661-90-0
    Chemical Formula: C21H13I6NO5
    Molecular Weight: 1120.76
    Category: Reference Standards/API Drug Metabolites/EP Impurities/USP Impurities
    Literature:
    Application: Levothyroxine EP Impurity F ; Levothyroxine T6 Impurity (USP) ;O-(4-Hydroxy-3,5-diiodophenyl)thyroxine ;(2S)-2-Amino-3-[4-[4-(4-hydroxy-3,5-diiodophenoxy)-3,5-diiodophenoxy]-3,5-diiodophenyl]propanoic acid | 911661-90-0 is useful as reference Impurity standard
    Levothyroxine EP Impurity F ; Levothyroxine T6 Impurity (USP) ;O-(4-Hydroxy-3,5-diiodophenyl)thyroxine ;(2S)-2-Amino-3-[4-[4-(4-hydroxy-3,5-diiodophenoxy)-3,5-diiodophenoxy]-3,5-diiodophenyl]propanoic acid  | 911661-90-0
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    Product Name : Levothyroxine EP Impurity H ; T4-Benzoic Acid (USP) ;Levothyroxine Benzoic Acid Impurity ; 4-(4-Hydroxy-3,5-diiodophenoxy)-3,5-diiodobenzoic acid | 2055-97-2

    Code: JCLTX-15
    CAS: 2055-97-2
    Chemical Formula: C13H6I4O4
    Molecular Weight: 733.80
    Category: Reference Standards/API Drug Metabolites/EP Impurities/USP Impurities
    Literature:
    Application: Levothyroxine EP Impurity H ; T4-Benzoic Acid (USP) ;Levothyroxine Benzoic Acid Impurity ; 4-(4-Hydroxy-3,5-diiodophenoxy)-3,5-diiodobenzoic acid | 2055-97-2  is useful as reference Impurity standard
    Levothyroxine EP Impurity H ; T4-Benzoic Acid (USP) ;Levothyroxine Benzoic Acid Impurity ; 4-(4-Hydroxy-3,5-diiodophenoxy)-3,5-diiodobenzoic acid  |  2055-97-2
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    Product Name : Levothyroxine EP Impurity I ;Levothyroxine Benzaldehyde Impurity ;T4-Aldehyde (USP) ; 4-(4-Hydroxy-3,5-diiodophenoxy)-3,5-diiodobenzaldehyde | 2016-06-0

    Code: JCLTX-14
    CAS:  2016-06-0
    Chemical Formula: C13H6I4O3
    Molecular Weight: 717.80
    Category: Reference Standards/API Drug Metabolites/EP Impurities/USP Impurities
    Literature:
    Application: Levothyroxine EP Impurity I ;Levothyroxine Benzaldehyde Impurity ;T4-Aldehyde (USP) ; 4-(4-Hydroxy-3,5-diiodophenoxy)-3,5-diiodobenzaldehyde | 2016-06-0  is useful as reference Impurity standard
    Levothyroxine EP Impurity I ;Levothyroxine Benzaldehyde Impurity ;T4-Aldehyde (USP) ; 4-(4-Hydroxy-3,5-diiodophenoxy)-3,5-diiodobenzaldehyde   |  2016-06-0
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    Product Name : Levothyroxine EP Impurity J ; 3,3’-Diiodo-L-Thyronine ;(2S)-2-Amino-3-[4-(4-hydroxy-3-iodophenoxy)-3-iodophenyl] propanoic acid | 4604-41-5

    Code: JCLTX-13
    CAS: 4604-41-5
    Chemical Formula: C15H13I2NO4
    Molecular Weight: 525.08
    Category: Reference Standards/API Drug Metabolites/EP Impurities/USP Impurities
    Literature:
    Application: Levothyroxine EP Impurity J ; 3,3’-Diiodo-L-Thyronine ;(2S)-2-Amino-3-[4-(4-hydroxy-3-iodophenoxy)-3-iodophenyl] propanoic acid | 4604-41-5   is useful as reference Impurity standard
    Levothyroxine EP Impurity J ; 3,3’-Diiodo-L-Thyronine ;(2S)-2-Amino-3-[4-(4-hydroxy-3-iodophenoxy)-3-iodophenyl] propanoic acid   | 4604-41-5
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    Product Name : Levothyroxine EP Impurity K ;3,3’,5’-Triiodo-L-Thyronine ;(2S)-2-Amino-3-[4-(4-hydroxy-3,5-diiodophenoxy)-3-iodophenyl] propanoic acid | 5817-39-0

    Code: JCLTX-12
    CAS:  5817-39-0
    Chemical Formula: C15H12I3NO4
    Molecular Weight: 650.97
    Category: Reference Standards/API Drug Metabolites/EP Impurities/USP Impurities
    Literature:
    Application: Levothyroxine EP Impurity K ;3,3’,5’-Triiodo-L-Thyronine ;(2S)-2-Amino-3-[4-(4-hydroxy-3,5-diiodophenoxy)-3-iodophenyl] propanoic acid | 5817-39-0  is useful as reference Impurity standard
    Levothyroxine EP Impurity K ;3,3’,5’-Triiodo-L-Thyronine ;(2S)-2-Amino-3-[4-(4-hydroxy-3,5-diiodophenoxy)-3-iodophenyl] propanoic acid  |  5817-39-0
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    Product Name : Levothyroxine Ethyl Ester ;Ethyl 2-amino-3-(4-(4-hydroxy-3,5-diiodophenoxy)-3,5-diiodo phenyl) propanoate | 76353-71-4

    Code: JCLTX-11
    CAS:  76353-71-4
    Chemical Formula: C17H15I4NO4
    Molecular Weight: 804.92
    Category: Reference Standards/API Drug Metabolites/EP Impurities/USP Impurities
    Literature:
    Application: Levothyroxine Ethyl Ester ;Ethyl 2-amino-3-(4-(4-hydroxy-3,5-diiodophenoxy)-3,5-diiodo phenyl) propanoate | 76353-71-4   is useful as reference Impurity standard
    Levothyroxine Ethyl Ester ;Ethyl 2-amino-3-(4-(4-hydroxy-3,5-diiodophenoxy)-3,5-diiodo phenyl) propanoate   |  76353-71-4
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    Product Name : Levothyroxine Hydroxyphenoxy Aldehyde Impurity ;3,5-Diiodo Thyroaldehyde ; 4-(4-Hydroxy-phenoxy)-3,5-diiodobenzaldehyde | 2828-49-1

    Code: JCLTX-10
    CAS: 2828-49-1
    Chemical Formula: C13H8I2O3
    Molecular Weight: 466.01
    Category: Reference Standards/API Drug Metabolites/EP Impurities/USP Impurities
    Literature:
    Application: Levothyroxine Hydroxyphenoxy Aldehyde Impurity ;3,5-Diiodo Thyroaldehyde ; 4-(4-Hydroxy-phenoxy)-3,5-diiodobenzaldehyde | 2828-49-1  is useful as reference Impurity standard
    Levothyroxine Hydroxyphenoxy Aldehyde Impurity ;3,5-Diiodo Thyroaldehyde ; 4-(4-Hydroxy-phenoxy)-3,5-diiodobenzaldehyde  |  2828-49-1
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    Product Name : Levothyroxine Methoxyphenoxy Aldehyde Impurity ; 3,5-Diiodo Thyroaldehyde Methyl Ether ;4-(4-Methoxyphenoxy)-3,5-diiodobenzaldehyde | 69240-57-9

    Code: JCLTX-09
    CAS:  69240-57-9
    Chemical Formula: C14H10I2O3
    Molecular Weight: 480.04
    Category: Reference Standards/API Drug Metabolites/EP Impurities/USP Impurities
    Literature:
    Application: Levothyroxine Methoxyphenoxy Aldehyde Impurity ; 3,5-Diiodo Thyroaldehyde Methyl Ether ;4-(4-Methoxyphenoxy)-3,5-diiodobenzaldehyde | 69240-57-9  is useful as reference Impurity standard
    Levothyroxine Methoxyphenoxy Aldehyde Impurity ; 3,5-Diiodo Thyroaldehyde Methyl Ether ;4-(4-Methoxyphenoxy)-3,5-diiodobenzaldehyde   |  69240-57-9
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    Product Name : Levothyroxine Methyl Ester ; Methyl 2-amino-3-(4-(4-hydroxy-3,5-diiodophenoxy)-3,5-diiodo phenyl) propanoate | 32180-11-3

    Code:  JCLTX-08
    CAS: 32180-11-3
    Chemical Formula: C16H13I4NO4
    Molecular Weight: 709.9
    Category: Reference Standards/API Drug Metabolites/EP Impurities/USP Impurities
    Literature:
    Application: Levothyroxine Methyl Ester ; Methyl 2-amino-3-(4-(4-hydroxy-3,5-diiodophenoxy)-3,5-diiodo phenyl) propanoate | 32180-11-3  is useful as reference Impurity standard
    Levothyroxine Methyl Ester ; Methyl 2-amino-3-(4-(4-hydroxy-3,5-diiodophenoxy)-3,5-diiodo phenyl) propanoate   |  32180-11-3
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    Product Name : Levothyroxine Monochloro Impurity ;Monochloro Triiodo Thyronine (USP) ; (S)-2-Amino-3-[3-chloro-4-(4-hydroxy-3,5-diiodophenoxy)-5-iodophenyl] propanoic acid

    Code:  JCLTX-07
    CAS:  NA
    Chemical Formula: C15H11ClI3NO4
    Molecular Weight: 685.42
    Category: Reference Standards/API Drug Metabolites/EP Impurities/USP Impurities
    Literature:
    Application: Levothyroxine Monochloro Impurity ;Monochloro Triiodo Thyronine (USP) ; (S)-2-Amino-3-[3-chloro-4-(4-hydroxy-3,5-diiodophenoxy)-5-iodophenyl] propanoic acid  is useful as reference Impurity standard
    Levothyroxine Monochloro Impurity ;Monochloro Triiodo Thyronine (USP) ; (S)-2-Amino-3-[3-chloro-4-(4-hydroxy-3,5-diiodophenoxy)-5-iodophenyl] propanoic acid
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    Product Name : Levothyroxine N-Acetyl Impurity ;N-Acetyl-T4 (USP) ;N-Acetyl-O-(4-hydroxy-3,5-diiodophenyl)-3,5-diiodo-L-tyrosine | 26041-51-0

    Code: JCLTX-06
    CAS:  26041-51-0
    Chemical Formula: C17H13I4NO5
    Molecular Weight: 818.91
    Category: Reference Standards/API Drug Metabolites/EP Impurities/USP Impurities
    Literature:
    Application: Levothyroxine N-Acetyl Impurity ;N-Acetyl-T4 (USP) ;N-Acetyl-O-(4-hydroxy-3,5-diiodophenyl)-3,5-diiodo-L-tyrosine | 26041-51-0   is useful as reference Impurity standard
    Levothyroxine N-Acetyl Impurity ;N-Acetyl-T4 (USP) ;N-Acetyl-O-(4-hydroxy-3,5-diiodophenyl)-3,5-diiodo-L-tyrosine   |  26041-51-0
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    Product Name : Levothyroxine N-Formyl Impurity ; N-Formyl-T4 (USP) ;N-Formyl-O-(4-hydroxy-3,5-diiodophenyl)-3,5-diiodo-L-tyrosine | 671235-41-9

    Code: JC-LTX-05
    CAS:  671235-41-9
    Chemical Formula: C16H11I4NO5
    Molecular Weight: 804.88
    Category: Reference Standards/API Drug Metabolites/EP Impurities/USP Impurities
    Literature:
    Application:  Levothyroxine N-Formyl Impurity ; N-Formyl-T4 (USP) ;N-Formyl-O-(4-hydroxy-3,5-diiodophenyl)-3,5-diiodo-L-tyrosine | 671235-41-9  is useful as reference Impurity standard
    Levothyroxine N-Formyl Impurity ; N-Formyl-T4 (USP) ;N-Formyl-O-(4-hydroxy-3,5-diiodophenyl)-3,5-diiodo-L-tyrosine  |  671235-41-9
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    Product Name : Levothyroxine N-Methylamide (USP) ; (S)-2-Amino-3-[4-(4-hydroxy-3,5-diiodophenoxy)-3,5-diiodophenyl]-N-methylpropanamide |2088032-52-2

    Code: JCLTX-04
    CAS: 2088032-52-2
    Chemical Formula: C16H14I4N2O3
    Molecular Weight: 789.91
    Category: Reference Standards/API Drug Metabolites/EP Impurities/USP Impurities
    Literature:
    Application:Levothyroxine N-Methylamide (USP) ; (S)-2-Amino-3-[4-(4-hydroxy-3,5-diiodophenoxy)-3,5-diiodophenyl]-N-methylpropanamide  is useful as reference Impurity standard
    Levothyroxine N-Methylamide (USP) ; (S)-2-Amino-3-[4-(4-hydroxy-3,5-diiodophenoxy)-3,5-diiodophenyl]-N-methylpropanamide |2088032-52-2
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    Product Name : Levothyroxine O-Methyl Amine Impurity ; O-Methyl-Tetraiodothyroethylamine (USP) ; O-Methyl-T4-Amine (USP) ;2-[4-(3,5-Diiodo-4-methoxyphenoxy)-3,5-diiodophenyl]ethanamine

    Code:  JCLTX-03
    CAS: 
    Chemical Formula:  C15H13I4NO2
    Molecular Weight:  746.89
    Category: Reference Standards/API Drug Metabolites/EP Impurities/USP Impurities
    Literature:
    Application: Levothyroxine O-Methyl Amine Impurity ; O-Methyl-Tetraiodothyroethylamine (USP) ; O-Methyl-T4-Amine (USP) ;2-[4-(3,5-Diiodo-4-methoxyphenoxy)-3,5-diiodophenyl]ethanamine  is useful as reference Impurity standard
    Levothyroxine O-Methyl Amine Impurity ; O-Methyl-Tetraiodothyroethylamine (USP) ; O-Methyl-T4-Amine (USP) ;2-[4-(3,5-Diiodo-4-methoxyphenoxy)-3,5-diiodophenyl]ethanamine
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    Product Name : Levothyroxine Sodium ;Sodium 2-amino-3-(4-(4-hydroxy-3,5-diiodophenoxy)-3,5-diiodo phenyl) propanoate pentahydrate | 25416-65-3

    Code: JCLTX-02
    CAS: 25416-65-3
    Chemical Formula: C15H20I4NNaO9
    Molecular Weight: 888.93
    Category: Reference Standards/API Drug Metabolites/EP Impurities/USP Impurities
    Literature:
    Application: Levothyroxine Sodium ;Sodium 2-amino-3-(4-(4-hydroxy-3,5-diiodophenoxy)-3,5-diiodo phenyl) propanoate pentahydrate | 25416-65-3   is useful as reference Impurity standard
    Levothyroxine Sodium ;Sodium 2-amino-3-(4-(4-hydroxy-3,5-diiodophenoxy)-3,5-diiodo phenyl) propanoate pentahydrate   |  25416-65-3
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    Product Name : Levothyroxine T4-Hydroxyacetic Acid Impurity ;T4-Hydroxyacetic Acid (USP) ;2-Hydroxy-2-(4-(4-hydroxy-3,5-diiodophenoxy)-3,5-diiodophenyl)acetic acid | 93647-48-4

    Code: JCLTX-01
    CAS:  93647-48-4
    Chemical Formula: C14H8I4O5
    Molecular Weight: 763.83
    Category: Reference Standards/API Drug Metabolites/EP Impurities/USP Impurities
    Literature:
    Application: Levothyroxine T4-Hydroxyacetic Acid Impurity ;T4-Hydroxyacetic Acid (USP) ;2-Hydroxy-2-(4-(4-hydroxy-3,5-diiodophenoxy)-3,5-diiodophenyl)acetic acid | 93647-48-4   is useful as reference Impurity standard
    Levothyroxine T4-Hydroxyacetic Acid Impurity ;T4-Hydroxyacetic Acid (USP) ;2-Hydroxy-2-(4-(4-hydroxy-3,5-diiodophenoxy)-3,5-diiodophenyl)acetic acid |  93647-48-4