Fluvastatin

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Fluvastatin API Reference standards  and its EP Impurities, USP Impurities, non pharmacopeial Impurities, listed below & also offered custom synthesis for unknown Impurities. If require any contact info@drjcrbio.com, sales@drjcrbio.com

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    Product Name : 1-(4-fluorophenyl)-2-(isopropyl(phenyl)amino)ethanone | 93957-51-8

    Code: JCFST-10
    CAS: 93957-51-8
    Chemical Formula: C17H18FNO
    Molecular Weight: 271.32
    Category: Reference Standards/API Drug Metabolites/EP Impurities/USP Impurities
    Literature:
    Application:  1-(4-fluorophenyl)-2-(isopropyl(phenyl)amino)ethanone | 93957-51-8 is useful as reference Impurity standard.
    1-(4-fluorophenyl)-2-(isopropyl(phenyl)amino)ethanone | 93957-51-8
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    Product Name : Fluvastatin USP RC B ; (3R*,5S*)-Fluvastatin t-Butyl Ester ; 1,1-Dimethylethyl (3R*,5S*,6E)-7-[3-(4-fluorophenyl)-1-(1-methylethyl)-1H-indol-2-yl]-3,5-dihydroxyhept-6-enoate | 129332-29-2

    Code: JCFST-09
    CAS: 129332-29-2
    Chemical Formula: C28H34FNO4
    Molecular Weight: 467.57
    Category: Reference Standards/API Drug Metabolites/EP Impurities/USP Impurities
    Literature: Fuenfschilling, Peter C.; Hoehn, Pascale; Mutz, Jean-Paul [Organic Process Research and Development, 2007, vol. 11, # 1, p. 13 - 18], Tempkin, Orin; Abel, Stephan; Chen, Chung-Pin; Underwood, Russell; Prasad, Kapa; Chen, Kau-Ming; Repic, Oljan; Blacklock, Thomas J. [Tetrahedron, 1997, vol. 53, # 31, p. 10659 - 10670]
    Application:  Fluvastatin USP RC B ; (3R*,5S*)-Fluvastatin t-Butyl Ester ; 1,1-Dimethylethyl (3R*,5S*,6E)-7-[3-(4-fluorophenyl)-1-(1-methylethyl)-1H-indol-2-yl]-3,5-dihydroxyhept-6-enoate | 129332-29-2 is useful as reference Impurity standard.
    Fluvastatin USP RC B ; (3R*,5S*)-Fluvastatin t-Butyl Ester ; 1,1-Dimethylethyl (3R*,5S*,6E)-7-[3-(4-fluorophenyl)-1-(1-methylethyl)-1H-indol-2-yl]-3,5-dihydroxyhept-6-enoate | 129332-29-2
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    Product Name : Fluvastatin Sodium ; Sodium (3RS,5SR,6E)-7-[3-(4-fluorophenyl)-1-(1-methylethyl)-1H-indol-2-yl]-3,5-dihydroxyhept-6-enoate | 93957-55-2

    Code: JCFST-08
    CAS: 93957-55-2
    Chemical Formula:C24H25FNNaO4, xH2O
    Molecular Weight: 433.45
    Category: Reference Standards/API Drug Metabolites/EP Impurities/USP Impurities
    Literature: Panda; Srivastava; Bahadur [Journal of Physical Chemistry B, 2009, vol. 113, # 45, p. 15090 - 15100]
    Application: Fluvastatin Sodium ; Sodium (3RS,5SR,6E)-7-[3-(4-fluorophenyl)-1-(1-methylethyl)-1H-indol-2-yl]-3,5-dihydroxyhept-6-enoate | 93957-55-2  is useful as reference Impurity standard.
    Fluvastatin Sodium ; Sodium (3RS,5SR,6E)-7-[3-(4-fluorophenyl)-1-(1-methylethyl)-1H-indol-2-yl]-3,5-dihydroxyhept-6-enoate | 93957-55-2
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    Product Name : Fluvastatin EP Impurity G ; Fluvastatin BP Impurity G ; 3-(4-Fluorophenyl)-1-(1-methylethyl)-1H-indole-2-carbaldehyde | 101125-34-2

    Code: JCFST-07
    CAS:  101125-34-2
    Chemical Formula: C18H16FNO
    Molecular Weight: 281.32
    Category: Reference Standards/API Drug Metabolites/EP Impurities/USP Impurities
    Literature: Walkup, R. E.; Linder, J. [Tetrahedron Letters, 1985, vol. 26, # 18, p. 2155 , - 2158] , Niwa, Takashi; Ochiai, Hidenori; Watanabe, Yasuyoshi; Hosoya, Takamitsu [Journal of the American Chemical Society, 2015, vol. 137, # 45, p. 14313 - 14318]
    Application:  Fluvastatin EP Impurity G ; Fluvastatin BP Impurity G ; 3-(4-Fluorophenyl)-1-(1-methylethyl)-1H-indole-2-carbaldehyde | 101125-34-2 is useful as reference Impurity standard.
    Fluvastatin EP Impurity G ; Fluvastatin BP Impurity G ; 3-(4-Fluorophenyl)-1-(1-methylethyl)-1H-indole-2-carbaldehyde | 101125-34-2
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    Product Name : Fluvastatin EP Impurity F ; Fluvastatin BP Impurity F ; Fluvastatin 3-Hydroxy-4,6-Diene ; (4E,6E)-7-[3-(4-Fluorophenyl)-1-(1-methylethyl)-1H-indol-2-yl]-3-hydroxyhepta-4,6-dienoic acid | 1207963-21-0

    Code: JCFST-06
    CAS: 1207963-21-0
    Chemical Formula: C24H24FNO3
    Molecular Weight: 393.45
    Category: Reference Standards/API Drug Metabolites/EP Impurities/USP Impurities
    Literature: Tierxi (Nanjing) Pharmaceutical Research And Development Co., Ltd.; Chen Qiang; Ding Ya; Hu Yongzhu; Liu Chun; Wang Zhongyi CN106905218, 2017, A Location in patent: Paragraph 0042; 0043; 0057; 0058,
    Application:  Fluvastatin EP Impurity F ; Fluvastatin BP Impurity F ; Fluvastatin 3-Hydroxy-4,6-Diene ; (4E,6E)-7-[3-(4-Fluorophenyl)-1-(1-methylethyl)-1H-indol-2-yl]-3-hydroxyhepta-4,6-dienoic acid | 1207963-21-0 is useful as reference Impurity standard.
    Fluvastatin EP Impurity F ; Fluvastatin BP Impurity F ; Fluvastatin 3-Hydroxy-4,6-Diene ; (4E,6E)-7-[3-(4-Fluorophenyl)-1-(1-methylethyl)-1H-indol-2-yl]-3-hydroxyhepta-4,6-dienoic acid | 1207963-21-0
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    Product Name : Fluvastatin EP Impurity E ; Fluvastatin BP Impurity E ; 4,5-Anhydro Fluvastatin Racemate ; (6R)-6-[(E)-2-[3-(4-Fluorophenyl)-1-(1-methylethyl)-1H-indol-2-yl]ethenyl]-4-hydroxy-5,6-dihydro-2H-pyran-2-one | 920275-10-1

    Code: JCFST-05
    CAS:920275-10-1
    Chemical Formula: C24H22FNO3
    Molecular Weight:391.43
    Category: Reference Standards/API Drug Metabolites/EP Impurities/USP Impurities
    Literature:
    Application: Fluvastatin EP Impurity E ; Fluvastatin BP Impurity E ; 4,5-Anhydro Fluvastatin Racemate ; (6R)-6-[(E)-2-[3-(4-Fluorophenyl)-1-(1-methylethyl)-1H-indol-2-yl]ethenyl]-4-hydroxy-5,6-dihydro-2H-pyran-2-one | 920275-10-1 is useful as reference Impurity standard.
    Fluvastatin EP Impurity E ; Fluvastatin BP Impurity E ; 4,5-Anhydro Fluvastatin Racemate ; (6R)-6-[(E)-2-[3-(4-Fluorophenyl)-1-(1-methylethyl)-1H-indol-2-yl]ethenyl]-4-hydroxy-5,6-dihydro-2H-pyran-2-one | 920275-10-1
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    Product Name : Fluvastatin EP Impurity D ;Fluvastatin BP Impurity D ; rac 5-Keto Fluvastatin ; (E)-(+/-)-7-[3-(4-Fluorophenyl)-1-(methylethyl)-1H-indol-2-yl]-3-hydroxy-5-oxo-6-heptenoic acid | 1160169-39-0

    Code: JCFST-04
    CAS: 1160169-39-0
    Chemical Formula: C24H24FNO4
    Molecular Weight: 409.45
    Category: Reference Standards/API Drug Metabolites/EP Impurities/USP Impurities
    Literature:
    Application: Fluvastatin EP Impurity D ;Fluvastatin BP Impurity D ; rac 5-Keto Fluvastatin ; (E)-(+/-)-7-[3-(4-Fluorophenyl)-1-(methylethyl)-1H-indol-2-yl]-3-hydroxy-5-oxo-6-heptenoic acid | 1160169-39-0 is useful as reference Impurity standard.
    Fluvastatin EP Impurity D ;Fluvastatin BP Impurity D ; rac 5-Keto Fluvastatin ; (E)-(+/-)-7-[3-(4-Fluorophenyl)-1-(methylethyl)-1H-indol-2-yl]-3-hydroxy-5-oxo-6-heptenoic acid | 1160169-39-0
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    Product Name : Fluvastatin EP Impurity C; Fluvastatin BP Impurity C ; (3R,5S,6E)-7-[1-Ethyl-3-(4-fluorophenyl)-1H-indol-2-yl]-3,5-dihydroxyhept-6-enoic acid | 93936-64-2

    Code: JCFST-03
    CAS: 93936-64-2
    Chemical Formula: C23H24FNO4
    Molecular Weight: 397.44
    Category: Reference Standards/API Drug Metabolites/EP Impurities/USP Impurities
    Literature:
    Application: Fluvastatin EP Impurity C; Fluvastatin BP Impurity C ; (3R,5S,6E)-7-[1-Ethyl-3-(4-fluorophenyl)-1H-indol-2-yl]-3,5-dihydroxyhept-6-enoic acid | 93936-64-2 is useful as reference Impurity standard.
    Fluvastatin EP Impurity C; Fluvastatin BP Impurity C ; (3R,5S,6E)-7-[1-Ethyl-3-(4-fluorophenyl)-1H-indol-2-yl]-3,5-dihydroxyhept-6-enoic acid | 93936-64-2
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    Product Name : Fluvastatin EP Impurity B ;Fluvastatin BP Impurity B ; (3R,5S)-Fluvastatin t-Butyl Ester ; 1,1-Dimethylethyl (3R,5S,6E)-7-[3-(4-fluorophenyl)-1-(1-methylethyl)-1H-indol-2-yl]-3,5-dihydroxyhept-6-enoate | 194934-96-8

    Code: JCFST-02
    CAS: 194934-96-8
    Chemical Formula: C28H34FNO4
    Molecular Weight: 467.57
    Category: Reference Standards/API Drug Metabolites/EP Impurities/USP Impurities
    Literature:
    Application: Fluvastatin EP Impurity B ;Fluvastatin BP Impurity B ; (3R,5S)-Fluvastatin t-Butyl Ester ; 1,1-Dimethylethyl (3R,5S,6E)-7-[3-(4-fluorophenyl)-1-(1-methylethyl)-1H-indol-2-yl]-3,5-dihydroxyhept-6-enoate | 194934-96-8 is useful as reference Impurity standard.
    Fluvastatin EP Impurity B ;Fluvastatin BP Impurity B ; (3R,5S)-Fluvastatin t-Butyl Ester ; 1,1-Dimethylethyl (3R,5S,6E)-7-[3-(4-fluorophenyl)-1-(1-methylethyl)-1H-indol-2-yl]-3,5-dihydroxyhept-6-enoate | 194934-96-8
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    Product Name : Fluvastatin EP Impurity A ;Fluvastatin BP Impurity A ; (3RS,5RS,6E)-7-[3-(4-Fluorophenyl)-1-(1-methylethyl)-1H-indol-2-yl]-3,5-dihydroxyhept-6-enoic acid | 93957-54-1

    Code: JCFST-01
    CAS: 93957-54-1
    Chemical Formula: C24H25FNNaO4
    Molecular Weight: 433.45
    Category: Reference Standards/API Drug Metabolites/EP Impurities/USP Impurities
    Literature:
    Application: Fluvastatin EP Impurity A ;Fluvastatin BP Impurity A ; (3RS,5RS,6E)-7-[3-(4-Fluorophenyl)-1-(1-methylethyl)-1H-indol-2-yl]-3,5-dihydroxyhept-6-enoic acid | 93957-54-1 is useful as reference Impurity standard.
    Fluvastatin EP Impurity A ;Fluvastatin BP Impurity A ; (3RS,5RS,6E)-7-[3-(4-Fluorophenyl)-1-(1-methylethyl)-1H-indol-2-yl]-3,5-dihydroxyhept-6-enoic acid | 93957-54-1
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