Famotidine

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Famotidine API Reference standards  and its EP Impurities, USP Impurities, non pharmacopeial Impurities, listed below & also offered custom synthesis for unknown Impurities...      If have any requirement contact info@drjcrbio.com, sales@drjcrbio.com

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    Product Name : “Famotidine Sulfoxide ; 3-[[[2-[(Diaminomethylene)amino]thiazol-4-yl]methyl]sulfinyl]-N-aminosulfonylpropanimidamide | 90237-03-9 “

    Code: JCFMD-13
    CAS:  90237-03-9 "
    Chemical Formula: C8 H15 N7 O3 S3
    Molecular Weight: 353.44
    Category: Reference Standards/API Drug Metabolites/EP Impurities/USP Impurities
    Literature:
    Application:"Famotidine Sulfoxide ; 3-[[[2-[(Diaminomethylene)amino]thiazol-4-yl]methyl]sulfinyl]-N-aminosulfonylpropanimidamide | 90237-03-9 " is useful as reference Impurity standard.
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    Product Name : Famotidine EP Impurity H; Famotidine Isothiourea Impurity ;2-((2-(Diaminomethyleneamino)thiazol-4-yl)methyl)isothiourea dihydrochloride | 88046-01-9

    Code: JCFMD-12
    CAS: 88046-01-9
    Chemical Formula: C6H12Cl2N6S2
    Molecular Weight:303.24
    Category: Reference Standards/API Drug Metabolites/Famotidine EP Impurities/Famotidine USP Impurities
    Literature: Yanagisawa, Isao; Hirata, Yasufumi; Ishii, Yoshio, Journal of Medicinal Chemistry, 1987, vol. 30, # 10, p. 1787 - 1793; Junnarkar; Stavchansky, Pharmaceutical Research, 1995, vol. 12, # 4, p. 599 - 604
    Application: Famotidine EP Impurity H; Famotidine Isothiourea Impurity ;2-((2-(Diaminomethyleneamino)thiazol-4-yl)methyl)isothiourea dihydrochloride; Cas no 88046-01-9 useful as reference Impurity standard.
    Famotidine EP Impurity H; Famotidine Isothiourea Impurity ;2-((2-(Diaminomethyleneamino)thiazol-4-yl)methyl)isothiourea dihydrochloride | 88046-01-9
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    Product Name : Famotidine EP Impurity J; Methyl 3-[[[2-[(diaminomethylidene)amino]thiazol-4-yl]methyl]sulfanyl]propanoate | 76824-14-1

    Code: JCFMD-11
    CAS: 76824-14-1
    Chemical Formula: C9H14N4O2S2
    Molecular Weight: 274.36
    Category: Reference Standards/API Drug Metabolites/Famotidine EP Impurities/Famotidine USP Impurities
    Literature: EP3018125, 2016, A1, Location in patent: Paragraph 0613-0614
    Application: Famotidine EP Impurity J; Methyl 3-[[[2-[(diaminomethylidene)amino]thiazol-4-yl]methyl]sulfanyl]propanoate ;Cas no  76824-14-1 is useful as reference Impurity standard.
    Famotidine EP Impurity J; Methyl 3-[[[2-[(diaminomethylidene)amino]thiazol-4-yl]methyl]sulfanyl]propanoate | 76824-14-1
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    Product Name : Famotidine Sulfoxide ; 3-[[[2-[(Diaminomethylene)amino]-thiazol-4-yl]methyl]sulphinyl]-N-sulphamoylpropanamide |

    Code: JCFMD-10
    CAS: NA
    Chemical Formula: C8H15N7O3S3
    Molecular Weight: 353.44
    Category: Reference Standards/API Drug Metabolites/Famotidine EP Impurities/Famotidine USP Impurities
    Literature: WO2020/186006, 2020, A1, Location in patent: Page/Page column 208-209; WO2009/7015, 2009, A1, Location in patent: Page/Page column 76; Shnur, Rodney C.; Gallaschun, Randall J.; Singleton, David H.; Grissom, Martin; Sloan, Donald E.; et all., Journal of Medicinal Chemistry, 1991, vol. 34, # 7, p. 1975;
    Application: Famotidine Sulfoxide ; 3-[[[2-[(Diaminomethylene)amino]-thiazol-4-yl]methyl]sulphinyl]-N-sulphamoylpropanamide |is useful as reference Impurity standard.
    Famotidine Sulfoxide ; 3-[[[2-[(Diaminomethylene)amino]-thiazol-4-yl]methyl]sulphinyl]-N-sulphamoylpropanamide |
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    Product Name : Famotidine Impurity I ;3-[[[2-[(Diaminomethylene)amino]-thiazol-4-yl]methyl]sulphinyl]-N-sulphamoylpropanamide | 1020719-36-1

    Code: JCFMD-09
    CAS: 1020719-36-1
    Chemical Formula: C8H14N6O4S3
    Molecular Weight: 354.43
    Category: Reference Standards/API Drug Metabolites/Famotidine EP Impurities/Famotidine USP Impurities
    Literature: WO2020/186006, 2020, A1, Location in patent: Page/Page column 208-209; WO2009/7015, 2009, A1 Location in patent: Page/Page column 76; Shnur, Rodney C.; Gallaschun, Randall J.; Singleton, David H.; Grissom, Martin; Sloan, Donald E.; et all, Journal of Medicinal Chemistry, 1991, vol. 34, # 7, p. 1975 - 1982
    Application: Famotidine Impurity I ;3-[[[2-[(Diaminomethylene)amino]-thiazol-4-yl]methyl]sulphinyl]-N-sulphamoylpropanamide ; Cas no 1020719-36-1 is useful as reference Impurity standard.
    Famotidine Impurity I ;3-[[[2-[(Diaminomethylene)amino]-thiazol-4-yl]methyl]sulphinyl]-N-sulphamoylpropanamide | 1020719-36-1
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    Product Name : Famotidine EP Impurity G ; N-Cyano-3-[[[2-[(diaminomethylene)amino]thiazol-4-yl]methyl]sulphanyl]propanimidamide | 76823-97-7

    Code: JCFMD-08
    CAS: 76823-97-7
    Chemical Formula: C9H13N7S2
    Molecular Weight: 283.38
    Category: Reference Standards/API Drug Metabolites/Famotidine EP Impurities/Famotidine USP Impurities
    Literature: Yanagisawa; Hirata; Ishii., Journal of medicinal chemistry, 1984, vol. 27, # 7, p. 849 - 857;
    Application: Famotidine EP Impurity G ; N-Cyano-3-[[[2-[(diaminomethylene)amino]thiazol-4-yl]methyl]sulphanyl]propanimidamide ;Cas no  76823-97-7 is useful as reference Impurity standard.
    Famotidine EP Impurity G ; N-Cyano-3-[[[2-[(diaminomethylene)amino]thiazol-4-yl]methyl]sulphanyl]propanimidamide | 76823-97-7
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    Product Name : Famotidine EP Impurity F; 3-[[[2-[(Diaminomethylene)amino]thiazol-4-yl]methyl]sulphanyl]propanoic acid | 107880-74-0

    Code: JCFMD-07
    CAS: 107880-74-0
    Chemical Formula: C8H12N4O2S2
    Molecular Weight: 260.34
    Category: Reference Standards/API Drug Metabolites/Famotidine EP Impurities/Famotidine USP Impurities
    Literature: Yanagisawa, Isao; Hirata, Yasufumi; Ishii, Yoshio, Journal of Medicinal Chemistry, 1987, vol. 30, # 10, p. 1787 - 1793; Junnarkar; Stavchansky, Pharmaceutical Research, 1995, vol. 12, # 4, p. 599 - 604
    Application: Famotidine EP Impurity F ;3-[[[2-[(Diaminomethylene)amino]thiazol-4-yl]methyl]sulphanyl]propanoic acid ; Cas no  107880-74-0 is useful as reference Impurity standard.
    Famotidine EP Impurity F; 3-[[[2-[(Diaminomethylene)amino]thiazol-4-yl]methyl]sulphanyl]propanoic acid | 107880-74-0
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    Product Name : Famotidine EP Impurity E ; 2,2′-[Disulphanediylbis(methylenethiazole-4,2-diyl)]diguanidine | 129083-44-9

    Code: JCFMD-06
    CAS: 129083-44-9
    Chemical Formula: C10H14N8S4
    Molecular Weight: 374.53
    Category: Reference Standards/API Drug Metabolites/Famotidine EP Impurities/Famotidine USP Impurities
    Literature: Wu, Bin; Chen, Jiehao; Warren, J. David; Chen, Gong; Hua, Zihao; Danishefsky, Samuel J., Angewandte Chemie - International Edition, 2006, vol. 45, # 25, p. 4116 - 4125; Tan, Lei; Xia, Yu., Journal of the American Society for Mass Spectrometry, 2012, vol. 23, # 11, p. 2011 - 2019; WO2015/13169, 2015, A2., Location in patent: Page/Page column 122; 123; Ketcham, Roger; Schaumann, Ernst; Adiwidjaja, Gunadi., European Journal of Organic CheReference Standards/API Drug Metabolites/Famotidine EP Impurities/Famotidine USP Impuritiesmistry, 2001, # 9, p. 1695 - 1699
    Application:Famotidine EP Impurity E ; 2,2'-[Disulphanediylbis(methylenethiazole-4,2-diyl)]diguanidine; Cas no  129083-44-9  is useful as reference Impurity standard.
    Famotidine EP Impurity E ; 2,2'-[Disulphanediylbis(methylenethiazole-4,2-diyl)]diguanidine | 129083-44-9
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    Product Name : Famotidine EP Impurity D ; 3-[[[2-[(Diaminomethylene)amino]thiazol-4-yl]methyl]sulphanyl]propanamide | 76824-16-3

    Code: JCFMD-05
    CAS: 76824-16-3
    Chemical Formula: C8H13N5OS2
    Molecular Weight: 259.35
    Category: Reference Standards/API Drug Metabolites/Famotidine EP Impurities/Famotidine USP Impurities
    Literature: Yanagisawa; Hirata; Ishii., Journal of medicinal chemistry, 1984, vol. 27, # 7, p. 849 - 857; Junnarkar; Stavchansky., Pharmaceutical Research, 1995, vol. 12, # 4, p. 599 - 604
    Application: Famotidine EP Impurity D ; 3-[[[2-[(Diaminomethylene)amino]thiazol-4-yl]methyl]sulphanyl]propanamide ; Cas no 76824-16-3 isuseful as reference Impurity standard.
    Famotidine EP Impurity D ; 3-[[[2-[(Diaminomethylene)amino]thiazol-4-yl]methyl]sulphanyl]propanamide | 76824-16-3
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    Product Name : Famotidine EP Impurity C; 3-[[[2-[(Diaminomethylene)amino]thiazol-4-yl]methyl]sulphanyl]-N-sulphamoylpropanamide | 76824-17-4

    Code: JCFMD-04
    CAS: 76824-17-4
    Chemical Formula: C8H14N6O3S3
    Molecular Weight: 338.43
    Category: Reference Standards/API Drug Metabolites/Famotidine EP Impurities/Famotidine USP Impurities
    Literature: Yanagisawa, Isao; Hirata, Yasufumi; Ishii, Yoshio., Journal of Medicinal Chemistry, 1987, vol. 30, # 10, p. 1787 - 1793
    Application: Famotidine EP Impurity C ;3-[[[2-[(Diaminomethylene)amino]thiazol-4-yl]methyl]sulphanyl]-N-sulphamoylpropanamide; Cas no  76824-17-4 is useful as reference Impurity standard.
    Famotidine EP Impurity C; 3-[[[2-[(Diaminomethylene)amino]thiazol-4-yl]methyl]sulphanyl]-N-sulphamoylpropanamide | 76824-17-4
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    Product Name : Famotidine EP Impurity B ; 3,5-bis[2-[[[2-(Diaminomethylene)amino]thiazol-4-yl]methyl]sulphanyl]ethyl]-4H-1,2,4,6-thiatriazine 1,1-dioxide | 89268-62-2

    Code: JCFMD-03
    CAS: 89268-62-2; 109467-08-5
    Chemical Formula: C16H23N11O2S5
    Molecular Weight: 561.75
    Category: Reference Standards/API Drug Metabolites/Famotidine EP Impurities/Famotidine USP Impurities
    Literature: Yanagisawa, Isao; Hirata, Yasufumi; Ishii, Yoshio., Journal of Medicinal Chemistry, 1987, vol. 30, # 10, p. 1787 - 1793
    Application: Famotidine EP Impurity B ; 3,5-bis[2-[[[2-(Diaminomethylene)amino]thiazol-4-yl]methyl]sulphanyl]ethyl]-4H-1,2,4,6-thiatriazine 1,1-dioxide; Cas no 89268-62-2 is useful as reference Impurity standard.
    Famotidine EP Impurity B ; 3,5-bis[2-[[[2-(Diaminomethylene)amino]thiazol-4-yl]methyl]sulphanyl]ethyl]-4H-1,2,4,6-thiatriazine 1,1-dioxide | 89268-62-2
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    Product Name : Famotidine EP Impurity A; Famotidine USP RC A ;3-[[[2-[(Diaminomethylene)amino]thiazol-4-yl]methyl]sulphanyl]propanimidamide dihydrochloride | 88061-72-7

    Code: JCFMD-02
    CAS: 88061-72-7
    Chemical Formula: C8H16Cl2N6S2
    Molecular Weight: 331.29
    Category: Reference Standards/API Drug Metabolites/Famotidine EP Impurities/Famotidine USP Impurities
    Literature: Zhong, L., et al.: J. Pharm. Biomed. Anal., 6, 1051 (1998), Amin, A., et al.: Anal. Lett., 35, 1851 (2002), Singh, S., et al.: J. Pharm. Sci., 91, 253 (2002),
    Application: Famotidine EP Impurity A; Famotidine USP RC A ;3-[[[2-[(Diaminomethylene)amino]thiazol-4-yl]methyl]sulphanyl]propanimidamide dihydrochloride ; CAS: 88061-72-7 useful as reference Impurity standard.
    Famotidine EP Impurity A; Famotidine USP RC A ;3-[[[2-[(Diaminomethylene)amino]thiazol-4-yl]methyl]sulphanyl]propanimidamide dihydrochloride | 88061-72-7
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    Product Name : Famotidine ; 3-[[[2-[(Diaminomethylene)amino]thiazol-4-yl]methyl]sulphanyl]-N’- sulphamoyl propanimidamide | 76824-35-6

    Code: JCFMD-01
    CAS: 76824-35-6
    Chemical Formula: C8H15N7O2S3
    Molecular Weight: 337.45
    Category: Reference Standards/API Drug Metabolites/Famotidine EP Impurities/Famotidine USP Impurities
    Literature: Yanagisawa, Isao; Hirata, Yasufumi; Ishii, Yoshio., Journal of Medicinal Chemistry, 1987, vol. 30, # 10, p. 1787 - 1793
    Application: Famotidine ; 3-[[[2-[(Diaminomethylene)amino]thiazol-4-yl]methyl]sulphanyl]-N'- sulphamoyl propanimidamide ;Cas no76824-35-6 is useful as reference Impurity standard.
    Famotidine ; 3-[[[2-[(Diaminomethylene)amino]thiazol-4-yl]methyl]sulphanyl]-N'- sulphamoyl propanimidamide | 76824-35-6
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