Diltiazem Hydrochloride

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Diltiazem Hydrochloride API Reference standards  and its EP Impurities, USP Impurities, non pharmacopeial Impurities, listed below & also offered custom synthesis for unknown Impurities. If require any contact info@drjcrbio.com, sales@drjcrbio.com

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    Product Name : Diltiazem O-Desacetyl-O-Desmethyl HCl ;  (2S,3S)-5-[2-(Dimethylamino)ethyl]-2,3-dihydro-3-hydroxy-2-(4-hydroxyphenyl)-1,5-benzothiazepin-4(5H)-one Hydrochloride | 96252-32-3

    Code: JCDGT-14
    CAS: 96252-32-3
    Chemical Formula: C19H23ClN2O3S
    Molecular Weight: 394.92
    Category: Reference Standards/API Drug Metabolites/EP Impurities/USP Impurities
    Literature:
    Application: Diltiazem O-Desacetyl-O-Desmethyl HCl ;  (2S,3S)-5-[2-(Dimethylamino)ethyl]-2,3-dihydro-3-hydroxy-2-(4-hydroxyphenyl)-1,5-benzothiazepin-4(5H)-one Hydrochloride | 96252-32-3 is useful as reference Impurity standard.
    Diltiazem O-Desacetyl-O-Desmethyl HCl ;  (2S,3S)-5-[2-(Dimethylamino)ethyl]-2,3-dihydro-3-hydroxy-2-(4-hydroxyphenyl)-1,5-benzothiazepin-4(5H)-one Hydrochloride | 96252-32-3
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    Product Name : Diltiazem N-Oxide O-Desacetyl Impurity ;  O-Desacetyl Diltiazem N-Oxide ; (2S,3S)-5-[2-(Dimethylamino)ethyl]-2-(4-methoxyphenyl)-4-oxo-2,3,4,5-tetrahydro-1,5-benzothiazepin-3-ol N-Oxide

    Code: JCDGT-13
    CAS: NA
    Chemical Formula: C20H24N2O4S
    Molecular Weight: 388.48
    Category: Reference Standards/API Drug Metabolites/EP Impurities/USP Impurities
    Literature:
    Application: Diltiazem N-Oxide O-Desacetyl Impurity ;  O-Desacetyl Diltiazem N-Oxide ; (2S,3S)-5-[2-(Dimethylamino)ethyl]-2-(4-methoxyphenyl)-4-oxo-2,3,4,5-tetrahydro-1,5-benzothiazepin-3-ol N-Oxide is useful as reference Impurity standard.
    Diltiazem N-Oxide O-Desacetyl Impurity ;  O-Desacetyl Diltiazem N-Oxide ; (2S,3S)-5-[2-(Dimethylamino)ethyl]-2-(4-methoxyphenyl)-4-oxo-2,3,4,5-tetrahydro-1,5-benzothiazepin-3-ol N-Oxide
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    Product Name : Diltiazem N-Oxide ;  (2S-cis)-3-(Acetyloxy)-5-[2-(dimethyloxidoamino)ethyl]-2,3-dihydro-2-(4- methoxyphenyl)-1,5-benzothiazepin-4(5H)-one | 142843-04-7 

    Code: JCDGT-12
    CAS: 142843-04-7
    Chemical Formula: C22H26N2O5S
    Molecular Weight: 430.52
    Category: Reference Standards/API Drug Metabolites/EP Impurities/USP Impurities
    Literature:
    Application: Diltiazem N-Oxide ;  (2S-cis)-3-(Acetyloxy)-5-[2-(dimethyloxidoamino)ethyl]-2,3-dihydro-2-(4- methoxyphenyl)-1,5-benzothiazepin-4(5H)-one | 142843-04-7 is useful as reference Impurity standard.
    Diltiazem N-Oxide ;  (2S-cis)-3-(Acetyloxy)-5-[2-(dimethyloxidoamino)ethyl]-2,3-dihydro-2-(4- methoxyphenyl)-1,5-benzothiazepin-4(5H)-one | 142843-04-7 
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    Product Name : Diltiazem N,N-DiDesmethyl HCl ; N,N-DiDesmethyl Diltiazem Hydrochloride ; (2S,3S)-5-[2-Aminoethyl]-2-(4-methoxyphenyl)-4-oxo-2,3,4,5-tetrahydro-1,5-benzothiazepin-3-yl acetate HCl | 116050-35-2

    Code: JCDGT-11
    CAS: 116050-35-2
    Chemical Formula: C20H23ClN2O4S
    Molecular Weight: 422.10671
    Category: Reference Standards/API Drug Metabolites/EP Impurities/USP Impurities
    Literature:
    Application:Diltiazem N,N-DiDesmethyl HCl ; N,N-DiDesmethyl Diltiazem Hydrochloride ; (2S,3S)-5-[2-Aminoethyl]-2-(4-methoxyphenyl)-4-oxo-2,3,4,5-tetrahydro-1,5-benzothiazepin-3-yl acetate HCl | 116050-35-2 is useful as reference Impurity standard.
    Diltiazem N,N-DiDesmethyl HCl ; N,N-DiDesmethyl Diltiazem Hydrochloride ; (2S,3S)-5-[2-Aminoethyl]-2-(4-methoxyphenyl)-4-oxo-2,3,4,5-tetrahydro-1,5-benzothiazepin-3-yl acetate HCl  | 116050-35-2
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    Product Name : Diltiazem HCl ; Diltiazem Hydrochloride ; (2S,3S)-5-[2-(Dimethylamino)ethyl]-2-(4-methoxyphenyl)-4-oxo-2,3,4,5-tetrahydro-1,5-benzothiazepin-3-yl acetate hydrochloride

    Code: JCDGT-10
    CAS: NA
    Chemical Formula: C22H27ClN2O4S
    Molecular Weight: 450.13801
    Category: Reference Standards/API Drug Metabolites/EP Impurities/USP Impurities
    Literature:
    Application: Diltiazem HCl ; Diltiazem Hydrochloride ; (2S,3S)-5-[2-(Dimethylamino)ethyl]-2-(4-methoxyphenyl)-4-oxo-2,3,4,5-tetrahydro-1,5-benzothiazepin-3-yl acetate hydrochloride is useful as reference Impurity standard.
    Diltiazem HCl ;  Diltiazem Hydrochloride ; (2S,3S)-5-[2-(Dimethylamino)ethyl]-2-(4-methoxyphenyl)-4-oxo-2,3,4,5-tetrahydro-1,5-benzothiazepin-3-yl acetate hydrochloride
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    Product Name : Diltiazem EP Impurity G ;Diltiazem USP Related Compound G ; N-Desmethyl O-Desacetyl Diltiazem ; (2S,3S)-5-[2-(Methylamino)ethyl]-2-(4-methoxyphenyl)-4-oxo-2,3,4,5-tetrahydro-1,5-benzothiazepin-3-ol | 81353-09-5

    Code: JCDGT-09
    CAS: 81353-09-5
    Chemical Formula: C19H22N2O3S
    Molecular Weight: 358.45
    Category: Reference Standards/API Drug Metabolites/EP Impurities/USP Impurities
    Literature:
    Application: Diltiazem EP Impurity G ;Diltiazem USP Related Compound G ; N-Desmethyl O-Desacetyl Diltiazem ; (2S,3S)-5-[2-(Methylamino)ethyl]-2-(4-methoxyphenyl)-4-oxo-2,3,4,5-tetrahydro-1,5-benzothiazepin-3-ol | 81353-09-5 is useful as reference Impurity standard.
    Diltiazem EP Impurity G ;Diltiazem USP Related Compound G ; N-Desmethyl O-Desacetyl Diltiazem ; (2S,3S)-5-[2-(Methylamino)ethyl]-2-(4-methoxyphenyl)-4-oxo-2,3,4,5-tetrahydro-1,5-benzothiazepin-3-ol | 81353-09-5
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    Product Name : Diltiazem EP Impurity F ;O-Desacetyl Diltiazem HCl; (2S,3S)-5-[2-(Dimethylamino)ethyl]-2-(4-methoxyphenyl)-4-oxo-2,3,4,5-tetrahydro-1,5-benzothiazepin-3-ol HCl | 23515-45-9

    Code: JCDGT-08
    CAS: 23515-45-9
    Chemical Formula:C20H24N2O3S.HCl
    Molecular Weight: 408.95
    Category: Reference Standards/API Drug Metabolites/EP Impurities/USP Impurities
    Literature:
    Application: Diltiazem EP Impurity F ;O-Desacetyl Diltiazem HCl; (2S,3S)-5-[2-(Dimethylamino)ethyl]-2-(4-methoxyphenyl)-4-oxo-2,3,4,5-tetrahydro-1,5-benzothiazepin-3-ol HCl | 23515-45-9 is useful as reference Impurity standard.
    Diltiazem EP Impurity F ;O-Desacetyl Diltiazem HCl; (2S,3S)-5-[2-(Dimethylamino)ethyl]-2-(4-methoxyphenyl)-4-oxo-2,3,4,5-tetrahydro-1,5-benzothiazepin-3-ol HCl | 23515-45-9
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    Product Name : Diltiazem EP Impurity E ; (2S,3S)-3-Hydroxy-2-(4-methoxyphenyl)-2,3-dihydro-1,5-benzothiazepin-4(5H)-one|42399-49-5

    Code: JCDGT-07
    CAS: 42399-49-5
    Chemical Formula: C16H15NO3S
    Molecular Weight:  301.36
    Category: Reference Standards/API Drug Metabolites/EP Impurities/USP Impurities
    Literature:
    Application: Diltiazem EP Impurity E ; (2S,3S)-3-Hydroxy-2-(4-methoxyphenyl)-2,3-dihydro-1,5-benzothiazepin-4(5H)-onevv;42399-49-5 is useful as reference Impurity standard.
    Diltiazem EP Impurity E ; (2S,3S)-3-Hydroxy-2-(4-methoxyphenyl)-2,3-dihydro-1,5-benzothiazepin-4(5H)-one|42399-49-5
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    Product Name : Diltiazem EP Impurity D ; N-Desmethyl Diltiazem Hydrochloride ; (2S,3S)-5-[2-(Methylamino)ethyl]-2-(4-methoxyphenyl)-4-oxo-2,3,4,5-tetrahydro-1,5-benzothiazepin-3-yl acetate HCl |  130606-60-9

    Code: JCDGT-06
    CAS: 130606-60-9
    Chemical Formula: C21H25ClN2O4S
    Molecular Weight: 436.12236
    Category: Reference Standards/API Drug Metabolites/EP Impurities/USP Impurities
    Literature:
    Application: Diltiazem EP Impurity D ; N-Desmethyl Diltiazem Hydrochloride ; (2S,3S)-5-[2-(Methylamino)ethyl]-2-(4-methoxyphenyl)-4-oxo-2,3,4,5-tetrahydro-1,5-benzothiazepin-3-yl acetate HCl |  130606-60-9 is useful as reference Impurity standard.
    Diltiazem EP Impurity D ; N-Desmethyl Diltiazem Hydrochloride ; (2S,3S)-5-[2-(Methylamino)ethyl]-2-(4-methoxyphenyl)-4-oxo-2,3,4,5-tetrahydro-1,5-benzothiazepin-3-yl acetate HCl |  130606-60-9
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    Product Name : Diltiazem EP Impurity C ; O-Desmethyl Diltiazem HCl ; (2S,3S)-5-[2-(Dimethylamino)ethyl]-2-(4-hydroxyphenyl)-4-oxo-2,3,4,5-tetrahydro-1,5-benzothiazepin-3-yl acetate HCl | 142926-07-6 

    Code: JCDGT-05
    CAS: 142926-07-6
    Chemical Formula: C21H25ClN2O4S
    Molecular Weight: 436.95
    Category: Reference Standards/API Drug Metabolites/EP Impurities/USP Impurities
    Literature:
    Application: Diltiazem EP Impurity C ; O-Desmethyl Diltiazem HCl ; (2S,3S)-5-[2-(Dimethylamino)ethyl]-2-(4-hydroxyphenyl)-4-oxo-2,3,4,5-tetrahydro-1,5-benzothiazepin-3-yl acetate HCl | 142926-07-6is useful as reference Impurity standard.
    Diltiazem EP Impurity C ; O-Desmethyl Diltiazem HCl ; (2S,3S)-5-[2-(Dimethylamino)ethyl]-2-(4-hydroxyphenyl)-4-oxo-2,3,4,5-tetrahydro-1,5-benzothiazepin-3-yl acetate HCl | 142926-07-6 
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    Product Name : Diltiazem EP Impurity B ; (2S,3S)-2-(4-Methoxyphenyl)-4-oxo-2,3,4,5-tetrahydro-1,5-benzothiazepin-3-yl acetate ; Des[5-(2-dimethylamino)ethyl] Diltiazem

    Code:  JCDGT-04
    CAS: NA
    Chemical Formula:  C18H17NO4S
    Molecular Weight: 343.70
    Category: Reference Standards/API Drug Metabolites/EP Impurities/USP Impurities
    Literature:
    Application: Diltiazem EP Impurity B ; (2S,3S)-2-(4-Methoxyphenyl)-4-oxo-2,3,4,5-tetrahydro-1,5-benzothiazepin-3-yl acetate ; Des[5-(2-dimethylamino)ethyl] Diltiazem is useful as reference Impurity standard.
    Diltiazem EP Impurity B ; (2S,3S)-2-(4-Methoxyphenyl)-4-oxo-2,3,4,5-tetrahydro-1,5-benzothiazepin-3-yl acetate ; Des[5-(2-dimethylamino)ethyl] Diltiazem
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    Product Name : Diltiazem EP Impurity A ;Diltiazem USP RC A ; Diltiazem (2R)-Isomer ; (2R,3S)-5-[2-(Dimethylamino)ethyl]-2-(4-methoxyphenyl)-4-oxo-2,3,4,5-tetrahydro-1,5-benzothiazepin-3-yl acetate |  103532-27-0 

    Code: JCDGT-03
    CAS: 103532-27-0
    Chemical Formula: C22H26N2O4S
    Molecular Weight: 414.52
    Category: Reference Standards/API Drug Metabolites/EP Impurities/USP Impurities
    Literature:
    Application: Diltiazem EP Impurity A ;Diltiazem USP RC A ; Diltiazem (2R)-Isomer ; (2R,3S)-5-[2-(Dimethylamino)ethyl]-2-(4-methoxyphenyl)-4-oxo-2,3,4,5-tetrahydro-1,5-benzothiazepin-3-yl acetate |  103532-27-0 is useful as reference Impurity standard.
    Diltiazem EP Impurity A ;Diltiazem USP RC A ;  Diltiazem (2R)-Isomer ; (2R,3S)-5-[2-(Dimethylamino)ethyl]-2-(4-methoxyphenyl)-4-oxo-2,3,4,5-tetrahydro-1,5-benzothiazepin-3-yl acetate |  103532-27-0 
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    Product Name : Diltiazem 2-Epimer O-Desacetyl N-Desdimethylaminoethyl Impurity ;O-Desacetyl N-Desdimethylaminoethyl Diltiazem 2-Epimer ; (2R,3S)-2-(4-Methoxyphenyl)-4-oxo-2,3,4,5-tetrahydro-1,5-benzothiazepin-3-ol

    Code: JCDGT-02
    CAS: NA
    Chemical Formula: C16H15NO3S
    Molecular Weight: 301.36
    Category: Reference Standards/API Drug Metabolites/EP Impurities/USP Impurities
    Literature:
    Application: Diltiazem 2-Epimer O-Desacetyl N-Desdimethylaminoethyl Impurity ;O-Desacetyl N-Desdimethylaminoethyl Diltiazem 2-Epimer ; (2R,3S)-2-(4-Methoxyphenyl)-4-oxo-2,3,4,5-tetrahydro-1,5-benzothiazepin-3-ol is useful as reference Impurity standard.
    Diltiazem 2-Epimer O-Desacetyl N-Desdimethylaminoethyl Impurity ;O-Desacetyl N-Desdimethylaminoethyl Diltiazem 2-Epimer ;  (2R,3S)-2-(4-Methoxyphenyl)-4-oxo-2,3,4,5-tetrahydro-1,5-benzothiazepin-3-ol
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    Product Name : Diltiazem 2-Epimer O-Desacetyl Impurity ; O-Desacetyl Diltiazem 2-Epimer ; (2R,3S)-5-[2-(Dimethylamino)ethyl]-2-(4-methoxyphenyl)-4-oxo-2,3,4,5-tetrahydro-1,5-benzothiazepin-3-ol

    Code: JCDGT-01
    CAS: NA
    Chemical Formula: C20H24N2O3S
    Molecular Weight: 372.48
    Category: Reference Standards/API Drug Metabolites/EP Impurities/USP Impurities
    Literature:
    Application: Diltiazem 2-Epimer O-Desacetyl Impurity ; O-Desacetyl Diltiazem 2-Epimer ; (2R,3S)-5-[2-(Dimethylamino)ethyl]-2-(4-methoxyphenyl)-4-oxo-2,3,4,5-tetrahydro-1,5-benzothiazepin-3-ol is useful as reference Impurity standard.
    Diltiazem 2-Epimer O-Desacetyl Impurity ; O-Desacetyl Diltiazem 2-Epimer ; (2R,3S)-5-[2-(Dimethylamino)ethyl]-2-(4-methoxyphenyl)-4-oxo-2,3,4,5-tetrahydro-1,5-benzothiazepin-3-ol