Darifenacin

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Darifenacin API Reference standards  and its EP Impurities, USP Impurities, non pharmacopeial Impurities, listed below & also offered custom synthesis for unknown Impurities. If require any contact info@drjcrbio.com, sales@drjcrbio.com

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    Product Name : Darifenacin Vinyl Impurity ; 5-Vinylbenzofuran

     Code :  JCDFN-23
     CAS :  NA
     Formula :  C10H8O
     M.Wt :  144.17
     Category :  Darifenacin
    Darifenacin Vinyl Impurity ; 5-Vinylbenzofuran
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    Product Name : Darifenacin Pyrrolidinium Dimer Impurity ; (3S)-3-(2-Amino-2-oxo-1,1-diphenylethyl)-1,1-bis[2-(2,3-dihydro-5-benzofuranyl)ethyl]pyrrolidinium Bromide| 1396968-57-2

     Code :  JCDFN-22
     CAS :  1396968-57-2
     Formula :  C38H41BrN2O3
     M.Wt :  653.65
     Category :  Impurity
    Darifenacin Pyrrolidinium Dimer Impurity ; (3S)-3-(2-Amino-2-oxo-1,1-diphenylethyl)-1,1-bis[2-(2,3-dihydro-5-benzofuranyl)ethyl]pyrrolidinium Bromide| 1396968-57-2
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    Product Name : Darifenacin Pyrrolidin Carboxylic Acid Impurity ; (S)-2,2-Diphenyl-2-(pyrrolidin-3-yl)acetic acid

     Code :  JCDFN-21
     CAS :  NA
     Formula :  C18H19NO2
     M.Wt :  281.35
     Category :  Impurity
    Darifenacin Pyrrolidin Carboxylic Acid Impurity ; (S)-2,2-Diphenyl-2-(pyrrolidin-3-yl)acetic acid
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    Product Name : Darifenacin Nitrile Impurity ;Darifenacin Impurity C ; (3S)-1-[2-(2,3-Dihydro-5-benzofuranyl)ethyl]-α,α-diphenyl-3-pyrrolidine acetonitrile HCl | 252317-48-9 

     Code :  JCDFN-20
     CAS :  252317-48-9
     Formula :  C28H29ClN2O
     M.Wt :  445.00
     Category :  Impurity
    Darifenacin Nitrile Impurity ;Darifenacin Impurity C ; (3S)-1-[2-(2,3-Dihydro-5-benzofuranyl)ethyl]-α,α-diphenyl-3-pyrrolidine acetonitrile HCl  | 252317-48-9 
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    Product Name : Darifenacin N-Oxide Impurity ; (S)-2-[ 1-[2-(2,3-Dihydrobenzofuran-5-yl)ethyl]-1 -oxidopyrrolidin-3-yl]-2,2-diphenyl acetamide | 1391080-40-2 

     Code :  JCDFN-19
     CAS :  1391080-40-2
     Formula :  C28H30N2O3
     M.Wt :  442.55
     Category :  Impurity
    Darifenacin N-Oxide Impurity ; (S)-2-[ 1-[2-(2,3-Dihydrobenzofuran-5-yl)ethyl]-1 -oxidopyrrolidin-3-yl]-2,2-diphenyl acetamide | 1391080-40-2 
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    Product Name : Darifenacin DBE Isomer ;Darifenacin DBE Isomer ; (S)-2-(3-Pyrrolidinyl)-2,2-diphenyl-N-[2-(2,3-dihydrobenzfuran-5-yl)ethyl] acetamide

     Code :  JCDFN-18
     CAS :  NA
     Formula :  C28H30N2O2
     M.Wt :  426.55
     Category :  Impurity
    Darifenacin DBE Isomer ;Darifenacin DBE Isomer ; (S)-2-(3-Pyrrolidinyl)-2,2-diphenyl-N-[2-(2,3-dihydrobenzfuran-5-yl)ethyl] acetamide
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    Product Name : Darifenacin Cyano Pyrrolidine Impurity ; (S)-3-(Cyanodiphenylmethyl)-pyrrolidine HBr | 194602-27-2

     Code :  JCDFN-17
     CAS :  194602-27-2
     Formula :  C18H19BrN2
     M.Wt :  343.26
     Category :  Impurity
    Darifenacin Cyano Pyrrolidine Impurity ; (S)-3-(Cyanodiphenylmethyl)-pyrrolidine HBr | 194602-27-2
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    Product Name : Darifenacin Carboxylic Acid Impurity ; (S)-2-(1-(2-(2,3-Dihydrobenzofuran-5-yl)ethyl)pyrrolidin-3-yl)-2,2-diphenylacetic acid hydrobromid

     Code : JCDFN-16
     CAS : 1048979-16-3
     Formula : C28H30BrNO3
     M.Wt : 508.45
     Category :  Impurity
    Darifenacin Carboxylic Acid Impurity ; (S)-2-(1-(2-(2,3-Dihydrobenzofuran-5-yl)ethyl)pyrrolidin-3-yl)-2,2-diphenylacetic acid hydrobromid
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    Product Name : Darifenacin 7-Bromoethyl Impurity ; 7-(2-Bromoethyl)-2,3-dihydrobenzofuran

     Code :  JCDFN-15
     CAS :  NA
     Formula :  C10H11BrO
     M.Wt :  227.1
     Category :  Impurity
    Darifenacin 7-Bromoethyl Impurity ; 7-(2-Bromoethyl)-2,3-dihydrobenzofuran
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    Product Name : Darifenacin 7-Bromo Analog ; (S)-2-(1-(2-(7-Bromo-2,3-dihydrobenzofuran-5-yl)ethyl)pyrrolidin-3-yl)-2,2-diphenylacetamide

     Code :  JCDFN-14
     CAS :  NA
     Formula :  C28H30Br2N2O2
     M.Wt :  586.36
     Category :  Impurity
    Darifenacin 7-Bromo Analog ; (S)-2-(1-(2-(7-Bromo-2,3-dihydrobenzofuran-5-yl)ethyl)pyrrolidin-3-yl)-2,2-diphenylacetamide
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    Product Name : Darifenacin 4-Hydroxy Impurity ; (S)-2-(1-(3-(2-Bromoethyl)-4-hydroxyphenethyl)pyrrolidin-3-yl)-2,2-diphenylacetamide hydrobromide

     Code :  JCDFN-13
     CAS :  NA
     Formula :  C28H32Br2N2O2
     M.Wt :  588.37
     Category :  Impurity
    Darifenacin 4-Hydroxy Impurity ; (S)-2-(1-(3-(2-Bromoethyl)-4-hydroxyphenethyl)pyrrolidin-3-yl)-2,2-diphenylacetamide hydrobromide
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    Product Name : Darifenacin 3-Hydroxy Impurity ; 3-Hydroxy Darifenacin ; 2-{1-[2-(2,3-Dihydro-3-hydroxy-5-benzofuranyl)ethyl]-pyrrolidin-3(S)-yl}-2,2-diphenyl-acetamide | 206048-82-0 

     Code :  JCDFN-12
     CAS :  206048-82-0
     Formula :  C28H30N2O3
     M.Wt :  442.55
     Category :  Impurity
    Darifenacin 3-Hydroxy Impurity ; 3-Hydroxy Darifenacin ; 2-{1-[2-(2,3-Dihydro-3-hydroxy-5-benzofuranyl)ethyl]-pyrrolidin-3(S)-yl}-2,2-diphenyl-acetamide | 206048-82-0 
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    Product Name : Darifenacin 2,3-Dehydro Bromo Impurity; 5-(2-Bromoethyl)benzofuran

     Code :  JCDFN-11
     CAS :  NA
     Formula :  C10H9BrO
     M.Wt :  225.08
     Category :  Impurity
    Darifenacin 2,3-Dehydro Bromo Impurity;  5-(2-Bromoethyl)benzofuran
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    Product Name : Darifenacin R-Isomer ; (R)-2-[1-[2-(2,3-Dihydrobenzfuran-5-yl)ethyl]-3-pyrrolidinyl]-2,2-diphenylacetamide HBr

     Code  : JCDFN-10
     CAS  : NA
     Formula  : C28H31BrN2O2
     M.Wt  : 507.46
     Category  : Impurity
     
    Darifenacin R-Isomer ; (R)-2-[1-[2-(2,3-Dihydrobenzfuran-5-yl)ethyl]-3-pyrrolidinyl]-2,2-diphenylacetamide HBr
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    Product Name : Darifenacin Pyrrolidine Impurity (S)-Isomer ; (S)-2-(3-Pyrrolidinyl)-2,2-diphenylacetamide L-tartrate ; (S)-2,2-Diphenyl-2-(pyrrolidine-3-yl)acetamide L-tartrate | 134002-26-9

     Code  : JCDFN-09
     CAS  : 134002-26-9
     Formula  : C22H26N2O7
     M.Wt  : 430.45
     Category  : Impurity
    Darifenacin Pyrrolidine Impurity (S)-Isomer ; (S)-2-(3-Pyrrolidinyl)-2,2-diphenylacetamide L-tartrate ; (S)-2,2-Diphenyl-2-(pyrrolidine-3-yl)acetamide L-tartrate | 134002-26-9
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    Product Name : Darifenacin Pyrrolidine Impurity Racemate ; 2-(3-Pyrrolidinyl)-2,2-diphenylacetamide ; 2,2-Diphenyl-2-(pyrrolidine-3-yl)acetamide | 103887-32-7

     Code  : JCDFN-08
     CAS  : 103887-32-7
     Formula  : C18H20N2O
     M.Wt  : 280.36 
     Category  : Impurity
     
    Darifenacin Pyrrolidine Impurity Racemate ; 2-(3-Pyrrolidinyl)-2,2-diphenylacetamide ; 2,2-Diphenyl-2-(pyrrolidine-3-yl)acetamide | 103887-32-7
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    Product Name : Darifenacin HBr ; (S)-2-[1-[2-(2,3-Dihydrobenzfuran-5-yl)ethyl]-3-pyrrolidinyl]-2,2-diphenylacetamide HBr | 133099-07-7

     Code  : JCDFN-07
     CAS  : 133099-07-7
     Formula  : C28H31BrN2O2
     M.Wt  : 507.46
     Category  : Impurity
     
    Darifenacin HBr ; (S)-2-[1-[2-(2,3-Dihydrobenzfuran-5-yl)ethyl]-3-pyrrolidinyl]-2,2-diphenylacetamide HBr | 133099-07-7
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    Product Name : Darifenacin Dimer-2 Impurity ;Darifenacin Impurity D ; (S)-2-[1-[2-(2,3-Dihydrobenzfuran-5-yl)ethyl]-3-pyrrolidinyl]-2,2-diphenyl-N-[2-(2,3-dihydrobenzfuran-5-yl)ethyl]acetamide HCl

     Code  : JCDFN-06
     CAS  : NA
     Formula  : C38H41ClN2O3
     M.Wt  : 609.20
     Category  : Impurity
     
    Darifenacin Dimer-2 Impurity ;Darifenacin Impurity D ; (S)-2-[1-[2-(2,3-Dihydrobenzfuran-5-yl)ethyl]-3-pyrrolidinyl]-2,2-diphenyl-N-[2-(2,3-dihydrobenzfuran-5-yl)ethyl]acetamide HCl
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    Product Name : Darifenacin Dimer-1 Impurity ; (S)-2-(3-Pyrrolidinyl)-2,2-diphenyl-N,N-bis[2-(2,3-dihydrobenzfuran-5-yl)ethyl]acetamide

     Code  : JCDFN-05
     CAS  : NA
     Formula  : C38H40N2O3
     M.Wt  : 572.74
     Category  : Impurity
     
    Darifenacin Dimer-1 Impurity ; (S)-2-(3-Pyrrolidinyl)-2,2-diphenyl-N,N-bis[2-(2,3-dihydrobenzfuran-5-yl)ethyl]acetamide
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    Product Name : Darifenacin Dehydro Impurity ;2,3-Dehydro Darifenacin HBr ; (S)-2-[1-[2-(Benzfuran-5-yl)ethyl]-3-pyrrolidinyl]-2,2-diphenylacetamide HBr | 943034-52-4

     Code  : JCDFN-04
     CAS  : 943034-52-4
     Formula  : C28H29BrN2O2
     M.Wt  : 505.45
     Category  : Impurity
     
    Darifenacin Dehydro Impurity ;2,3-Dehydro Darifenacin HBr ; (S)-2-[1-[2-(Benzfuran-5-yl)ethyl]-3-pyrrolidinyl]-2,2-diphenylacetamide HBr | 943034-52-4
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    Product Name : C Cyano t-BOC Impurity ;Darifenacin Cyano Impurity ; 3-(Cyanodiphenylmethyl)-1-pyrrolidinecarboxylic acid t-butyl ester | 1159977-31-7

     Code  : JCDFN-03
     CAS  : 1159977-31-7
     Formula  : C23H26N2O2
     M.Wt  : 362.46
     Category  : Impurity
     
    C Cyano t-BOC Impurity ;Darifenacin Cyano Impurity ; 3-(Cyanodiphenylmethyl)-1-pyrrolidinecarboxylic acid t-butyl ester | 1159977-31-7
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    Product Name : Darifenacin 5-Carboxymethyl Impurity/ 69999-16-2

    Code: JCDFN-24
    CAS: 69999-16-2
    Chemical Formula: C10H10O3
    Molecular Weight: C10H10O3
    Category: Darifenacine  API Drug Metabolites/ EP Impurities/nitroso amine USP Impurities
    Literature:
    Application: (S)-2-(1-nitrosopyrrolidin-3-yl)-2,2-diphenylacetonitrile is useful as reference Impurity standard.
     
    Darifenacin 5-Carboxymethyl Impurity/ 69999-16-2
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    Product Name : Darifenacin 5-Bromoethyl Impurity ;5-Bromoethyl-2,3-Dihydrobenzofuran ; 5-(2-Bromoethyl)-2,3-dihydrobenzofuran ; 2-(2,3-Dihydrobenzfuran-5-yl)bromoethane | 127264-14-6

     Code  : JCDFN-01
     CAS  : 127264-14-6
     Formula  : C10H11BrO
     M.Wt  : 227.10
     Category  : Impurity
     
    Darifenacin 5-Bromoethyl Impurity ;5-Bromoethyl-2,3-Dihydrobenzofuran ; 5-(2-Bromoethyl)-2,3-dihydrobenzofuran ; 2-(2,3-Dihydrobenzfuran-5-yl)bromoethane |  127264-14-6