Apixaban

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Apixaban API Reference standards  and its EP Impurities, USP Impurities, non pharmacopeial Impurities, listed below & also offered custom synthesis for unknown Impurities. If require any contact info@drjcrbio.com, sales@drjcrbio.com

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    Product Name : Apixaban Impurity 89 Synonym:(Z)-ethyl 2-chloro-2-(2-(4-methoxyphenyl)-2-nitrosohydrazono)acetate

    Code: JCAPX-12
    CAS: NA
    Chemical Formula: C11H11Cl3N2O3
    Molecular Weight: 325.5757
    Category: Reference Standards/API Drug Metabolites/EP Impurities/USP Impurities
    Literature:
    Application: Apixaban Impurity 89 Synonym:(Z)-ethyl 2-chloro-2-(2-(4-methoxyphenyl)-2-nitrosohydrazono)acetateis useful as reference Impurity standard.
    Apixaban Impurity 89 Synonym:(Z)-ethyl 2-chloro-2-(2-(4-methoxyphenyl)-2-nitrosohydrazono)acetate
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    Product Name : Apixaban ; 4,5,6,7-Tetrahydro-1-(4-methoxyphenyl)-7-oxo-6-[4-(2-oxo-1-piperidinyl) phenyl]-1H-pyrazolo[3,4-c]pyridine-3-carboxamide | 503612-47-3

    Code: JCAPX-11
    CAS: 503612-47-3
    Chemical Formula: C25H25N5O4
    Molecular Weight: 459.50
    Category: Reference Standards/API Drug Metabolites/EP Impurities/USP Impurities
    Literature:
    Application: Apixaban ; 4,5,6,7-Tetrahydro-1-(4-methoxyphenyl)-7-oxo-6-[4-(2-oxo-1-piperidinyl) phenyl]-1H-pyrazolo[3,4-c]pyridine-3-carboxamide | 503612-47-3 is useful as reference Impurity standard.
    Apixaban ; 4,5,6,7-Tetrahydro-1-(4-methoxyphenyl)-7-oxo-6-[4-(2-oxo-1-piperidinyl) phenyl]-1H-pyrazolo[3,4-c]pyridine-3-carboxamide  |  503612-47-3
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    Product Name : Apixaban 4,5-Dehydro Carboxamide ;Apixaban 4,5-Dehydro Amide ;6,7-Dihydro-1-(4-methoxyphenyl)-7-oxo-6-[4-(2-oxo-1-piperidinyl) phenyl]-1H-pyrazolo[3,4-c]pyridine-3-carboxamide | 1074549-89-5

    Code: JCAPX-10
    CAS: 1074549-89-5
    Chemical Formula: C25H23N5O4
    Molecular Weight: 457.48
    Category: Reference Standards/API Drug Metabolites/EP Impurities/USP Impurities
    Literature:
    Application: Apixaban 4,5-Dehydro Carboxamide ;Apixaban 4,5-Dehydro Amide ;6,7-Dihydro-1-(4-methoxyphenyl)-7-oxo-6-[4-(2-oxo-1-piperidinyl) phenyl]-1H-pyrazolo[3,4-c]pyridine-3-carboxamide | 1074549-89-5 is useful as reference Impurity standard.
    Apixaban 4,5-Dehydro Carboxamide ;Apixaban 4,5-Dehydro Amide ;6,7-Dihydro-1-(4-methoxyphenyl)-7-oxo-6-[4-(2-oxo-1-piperidinyl) phenyl]-1H-pyrazolo[3,4-c]pyridine-3-carboxamide  |  1074549-89-5
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    Product Name : Apixaban 4,5-Dehydro Carboxylic Acid ; 6,7-Dihydro-1-(4-methoxyphenyl)-7-oxo-6-[4-(2-oxo-1-piperidinyl) phenyl]-1H-pyrazolo[3,4-c]pyridine-3-carboxylic acid

    Code: JCAPX-09
    CAS: NA
    Chemical Formula: C25H22N4O5
    Molecular Weight: 458.47
    Category: Reference Standards/API Drug Metabolites/EP Impurities/USP Impurities
    Literature:
    Application: Apixaban 4,5-Dehydro Carboxylic Acid ; 6,7-Dihydro-1-(4-methoxyphenyl)-7-oxo-6-[4-(2-oxo-1-piperidinyl) phenyl]-1H-pyrazolo[3,4-c]pyridine-3-carboxylic acid is useful as reference Impurity standard.
    Apixaban 4,5-Dehydro Carboxylic Acid ; 6,7-Dihydro-1-(4-methoxyphenyl)-7-oxo-6-[4-(2-oxo-1-piperidinyl) phenyl]-1H-pyrazolo[3,4-c]pyridine-3-carboxylic acid
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    Product Name : Apixaban 4,5-Dehydro Carboxylic Acid Ethyl Ester ; 6,7-Dihydro-1-(4-methoxyphenyl)-7-oxo-6-[4-(2-oxo-1-piperidinyl) phenyl]-1H-pyrazolo[3,4-c]pyridine-3-carboxylic acid ethyl ester

    Code: JCAPX-08
    CAS: NA
    Chemical Formula: C27H26N4O5
    Molecular Weight: 486.52
    Category: Reference Standards/API Drug Metabolites/EP Impurities/USP Impurities
    Literature:
    Application: Apixaban 4,5-Dehydro Carboxylic Acid Ethyl Ester ; 6,7-Dihydro-1-(4-methoxyphenyl)-7-oxo-6-[4-(2-oxo-1-piperidinyl) phenyl]-1H-pyrazolo[3,4-c]pyridine-3-carboxylic acid ethyl ester  is useful as reference Impurity standard.
    Apixaban 4,5-Dehydro Carboxylic Acid Ethyl Ester ; 6,7-Dihydro-1-(4-methoxyphenyl)-7-oxo-6-[4-(2-oxo-1-piperidinyl) phenyl]-1H-pyrazolo[3,4-c]pyridine-3-carboxylic acid ethyl ester
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    Product Name : Apixaban Carboxylic Acid Impurity ;4,5,6,7-Tetrahydro-1-(4-methoxyphenyl)-7-oxo-6-[4-(2-oxo-1-piperidinyl) phenyl]-1H-pyrazolo[3,4-c]pyridine-3-carboxylic acid | 503614-92-4

    Code: JCAPX-07
    CAS: 503614-92-4
    Chemical Formula: C25H24N4O5
    Molecular Weight: 460.48
    Category: Reference Standards/API Drug Metabolites/EP Impurities/USP Impurities
    Literature:
    Application: Apixaban Carboxylic Acid Impurity ;4,5,6,7-Tetrahydro-1-(4-methoxyphenyl)-7-oxo-6-[4-(2-oxo-1-piperidinyl) phenyl]-1H-pyrazolo[3,4-c]pyridine-3-carboxylic acid | 503614-92-4 is useful as reference Impurity standard.
    Apixaban Carboxylic Acid Impurity ;4,5,6,7-Tetrahydro-1-(4-methoxyphenyl)-7-oxo-6-[4-(2-oxo-1-piperidinyl) phenyl]-1H-pyrazolo[3,4-c]pyridine-3-carboxylic acid  |  503614-92-4
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    Product Name : Apixaban Carboxylic Acid O-Desmethyl Impurity ;4,5,6,7-Tetrahydro-1-(4-hydroxyphenyl)-7-oxo-6-[4-(2-oxo-1-piperidinyl) phenyl]-1H-pyrazolo[3,4-c]pyridine-3-carboxylic acid

    Code: JCAPX-06
    CAS:  NA
    Chemical Formula: C24H22N4O5
    Molecular Weight: 446.46
    Category: Reference Standards/API Drug Metabolites/EP Impurities/USP Impurities
    Literature:
    Application: Apixaban Carboxylic Acid O-Desmethyl Impurity ;4,5,6,7-Tetrahydro-1-(4-hydroxyphenyl)-7-oxo-6-[4-(2-oxo-1-piperidinyl) phenyl]-1H-pyrazolo[3,4-c]pyridine-3-carboxylic acid is useful as reference Impurity standard.
    Apixaban Carboxylic Acid O-Desmethyl Impurity ;4,5,6,7-Tetrahydro-1-(4-hydroxyphenyl)-7-oxo-6-[4-(2-oxo-1-piperidinyl) phenyl]-1H-pyrazolo[3,4-c]pyridine-3-carboxylic acid
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    Product Name : Apixaban Chloro Impurity ;4,5,6,7-Tetrahydro-1-(4-chlorophenyl)-7-oxo-6-[4-(2-oxo-1-piperidinyl) phenyl]-1H-pyrazolo[3,4-c]pyridine-3-carboxamide

    Code: JCAPX-05
    CAS: NA
    Chemical Formula: C24H22ClN5O3
    Molecular Weight: 463.92
    Category: Reference Standards/API Drug Metabolites/EP Impurities/USP Impurities
    Literature:
    Application: Apixaban Chloro Impurity ;4,5,6,7-Tetrahydro-1-(4-chlorophenyl)-7-oxo-6-[4-(2-oxo-1-piperidinyl) phenyl]-1H-pyrazolo[3,4-c]pyridine-3-carboxamide is useful as reference Impurity standard.
    Apixaban Chloro Impurity ;4,5,6,7-Tetrahydro-1-(4-chlorophenyl)-7-oxo-6-[4-(2-oxo-1-piperidinyl) phenyl]-1H-pyrazolo[3,4-c]pyridine-3-carboxamide
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    Product Name : Apixaban Ethyl Ester Impurity ; 4,5,6,7-Tetrahydro-1-(4-methoxyphenyl)-7-oxo-6-[4-(2-oxo-1-piperidinyl) phenyl]-1H-pyrazolo[3,4-c]pyridine-3-carboxylic acid ethyl ester | 503614-91-3

    Code: JCAPX-04
    CAS: 503614-91-3
    Chemical Formula: C27H28N4O5
    Molecular Weight: 488.54
    Category: Reference Standards/API Drug Metabolites/EP Impurities/USP Impurities
    Literature:
    Application: Apixaban Ethyl Ester Impurity ; 4,5,6,7-Tetrahydro-1-(4-methoxyphenyl)-7-oxo-6-[4-(2-oxo-1-piperidinyl) phenyl]-1H-pyrazolo[3,4-c]pyridine-3-carboxylic acid ethyl ester | 503614-91-3 is useful as reference Impurity standard.
    Apixaban Ethyl Ester Impurity ; 4,5,6,7-Tetrahydro-1-(4-methoxyphenyl)-7-oxo-6-[4-(2-oxo-1-piperidinyl) phenyl]-1H-pyrazolo[3,4-c]pyridine-3-carboxylic acid ethyl ester  |  503614-91-3
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    Product Name : Apixaban Isopropyl Ester Impurity ;4,5,6,7-Tetrahydro-1-(4-methoxyphenyl)-7-oxo-6-[4-(2-oxo-1-piperidinyl) phenyl]-1H-pyrazolo[3,4-c]pyridine-3-carboxylic acid isopropyl ester

    Code: JCAPX-03
    CAS: NA
    Chemical Formula: C28H30N4O5
    Molecular Weight: 502.56
    Category: Reference Standards/API Drug Metabolites/EP Impurities/USP Impurities
    Literature:
    Application: Apixaban Isopropyl Ester Impurity ;4,5,6,7-Tetrahydro-1-(4-methoxyphenyl)-7-oxo-6-[4-(2-oxo-1-piperidinyl) phenyl]-1H-pyrazolo[3,4-c]pyridine-3-carboxylic acid isopropyl ester is useful as reference Impurity standard.
    Apixaban Isopropyl Ester Impurity ;4,5,6,7-Tetrahydro-1-(4-methoxyphenyl)-7-oxo-6-[4-(2-oxo-1-piperidinyl) phenyl]-1H-pyrazolo[3,4-c]pyridine-3-carboxylic acid isopropyl ester
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    Product Name : Apixaban O-Desmethyl Impurity ;4,5,6,7-Tetrahydro-1-(4-hydroxyphenyl)-7-oxo-6-[4-(2-oxo-1-piperidinyl) phenyl]-1H-pyrazolo[3,4-c]pyridine-3-carboxamide | 503612-76-8

    Code: JCAPX-02
    CAS: 503612-76-8
    Chemical Formula: C24H23N5O4
    Molecular Weight: 445.47
    Category: Reference Standards/API Drug Metabolites/EP Impurities/USP Impurities
    Literature:
    Application: Apixaban O-Desmethyl Impurity ;4,5,6,7-Tetrahydro-1-(4-hydroxyphenyl)-7-oxo-6-[4-(2-oxo-1-piperidinyl) phenyl]-1H-pyrazolo[3,4-c]pyridine-3-carboxamide | 503612-76-8 is useful as reference Impurity standard.
    Apixaban O-Desmethyl Impurity ;4,5,6,7-Tetrahydro-1-(4-hydroxyphenyl)-7-oxo-6-[4-(2-oxo-1-piperidinyl) phenyl]-1H-pyrazolo[3,4-c]pyridine-3-carboxamide  |  503612-76-8
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    Product Name : Apixaban Methyl Ester Impurity ;4,5,6,7-Tetrahydro-1-(4-methoxyphenyl)-7-oxo-6-[4-(2-oxo-1-piperidinyl) phenyl]-1H-pyrazolo[3,4-c]pyridine-3-carboxylic acid methyl ester | 1074365-84-6

    Code: JCAPX-01
    CAS: 1074365-84-6
    Chemical Formula: C26H26N4O5
    Molecular Weight: 474.51
    Category: Reference Standards/API Drug Metabolites/EP Impurities/USP Impurities
    Literature:
    Application: Apixaban Methyl Ester Impurity ;4,5,6,7-Tetrahydro-1-(4-methoxyphenyl)-7-oxo-6-[4-(2-oxo-1-piperidinyl) phenyl]-1H-pyrazolo[3,4-c]pyridine-3-carboxylic acid methyl ester | 1074365-84-6 is useful as reference Impurity standard.
    Apixaban Methyl Ester Impurity ;4,5,6,7-Tetrahydro-1-(4-methoxyphenyl)-7-oxo-6-[4-(2-oxo-1-piperidinyl) phenyl]-1H-pyrazolo[3,4-c]pyridine-3-carboxylic acid methyl ester  |  1074365-84-6