Apixaban

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Apixaban API Reference standards  and its EP Impurities, USP Impurities, non pharmacopeial Impurities, listed below & also offered custom synthesis for unknown Impurities. If require any contact info@drjcrbio.com, sales@drjcrbio.com

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    Product Name : Apixaban Impurity 139/1642569-42-3

    Code: JCAPX-31
    CAS: 1642569-42-3
    Chemical Formula: C20H17N5O5
    Molecular Weight: 407.38
    Category: Apixaban Reference Standards/API Drug Metabolites/EP Impurities/USP Impurities
    Literature:
    Application: 1-(4-methoxyphenyl)-6-(4-nitrophenyl)-7-oxo-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxamide/1642569-42-3 is useful as reference Impurity standard.
    Apixaban Impurity 139/1642569-42-3
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    Product Name : Apixaban Impurity 84/2816305-40-3

    Code: JCAPX-30
    CAS: 2816305-40-3
    Chemical Formula: C15H17N3O2
    Molecular Weight: 271.3
    Category: Apixaban Reference Standards/API Drug Metabolites/EP Impurities/USP Impurities
    Literature:
    Application: 1-(4-Aminophenyl)-3-morpholinopyridin-2(1H)-one; Apixaban Impurity 84/2816305-40-3Apixaban Stage II : Ethyl 6-(4-aminophenyl) 1-(4-methoxyphenyl)-7-oxo-4,5-dihydropyrazolo[3,4-c]pyridine-3-carboxylate; 503615-07-4 is useful as reference Impurity standard.
    Apixaban Impurity 84/2816305-40-3
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    Product Name : Apixaban Stage II : Ethyl 6-(4-aminophenyl) 1-(4-methoxyphenyl)-7-oxo-4,5-dihydropyrazolo[3,4-c]pyridine-3-carboxylate; 503615-07-4

    Code: JCAPX-29
    CAS: 503615-07-4
    Chemical Formula: C22H22N4O4
    Molecular Weight: 406.43
    Category: Apixaban Reference Standards/API Drug Metabolites/EP Impurities/USP Impurities
    Literature:
    Application: Apixaban Stage II : Ethyl 6-(4-aminophenyl) 1-(4-methoxyphenyl)-7-oxo-4,5-dihydropyrazolo[3,4-c]pyridine-3-carboxylate; 503615-07-4 is useful as reference Impurity standard.
    Apixaban Stage II : Ethyl 6-(4-aminophenyl) 1-(4-methoxyphenyl)-7-oxo-4,5-dihydropyrazolo[3,4-c]pyridine-3-carboxylate; 503615-07-4
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    Product Name : Apixaban di acid impurity; 6-(4-((4-carboxybutyl)amino)phenyl)-1-(4-methoxyphenyl)-7-oxo-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxylic acid; 2264018-89-3

    Code: JCAPX-28
    CAS: 2264018-89-3
    Chemical Formula: C25H26N4O6
    Molecular Weight: 478.50
    Category: Apixaban Reference Standards/API Drug Metabolites/EP Impurities/USP Impurities
    Literature:
    Application: Apixaban di acid impurity; 6-(4-((4-carboxybutyl)amino)phenyl)-1-(4-methoxyphenyl)-7-oxo-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxylic acid; 2264018-89-3 is useful as reference Impurity standard.
    Apixaban di acid impurity; 6-(4-((4-carboxybutyl)amino)phenyl)-1-(4-methoxyphenyl)-7-oxo-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxylic acid; 2264018-89-3
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    Product Name : Apixaban open chain amide; 6-(4-((5-amino-5-oxopentyl)amino)phenyl)-1-(4-methoxyphenyl)-7-oxo-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxamide; 2187409-01-2

    Code: JCAPX-27
    CAS: 2187409-01-2
    Chemical Formula: C25H28N6O4
    Molecular Weight: 476.54
    Category: Apixaban Reference Standards/API Drug Metabolites/EP Impurities/USP Impurities
    Literature:
    Application: Apixaban open chain amide; 6-(4-((5-amino-5-oxopentyl)amino)phenyl)-1-(4-methoxyphenyl)-7-oxo-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxamide; 2187409-01-2 is useful as reference Impurity standard.
    Apixaban open chain amide; 6-(4-((5-amino-5-oxopentyl)amino)phenyl)-1-(4-methoxyphenyl)-7-oxo-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxamide; 2187409-01-2
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    Product Name : Apixaban Open Chain Acid; 5-[[4-[3-(Aminocarbonyl)-1,4,5,7-tetrahydro-1-(4-methoxyphenyl)-7-oxo-6H-pyrazolo[3,4-c]pyridin-6-yl]phenyl]amino]pen tanoic Acid; 2206825-87-6; 503612-47-3

    Code: JCAPX-26
    CAS: 2206825-87-6
    Chemical Formula: C25H27N5O5
    Molecular Weight: 477.52
    Category: Apixaban Reference Standards/API Drug Metabolites/EP Impurities/USP Impurities
    Literature:
    Application: Apixaban Open Chain Acid; 5-[[4-[3-(Aminocarbonyl)-1,4,5,7-tetrahydro-1-(4-methoxyphenyl)-7-oxo-6H-pyrazolo[3,4-c]pyridin-6-yl]phenyl]amino]pentanoic Acid; 2206825-87-6; 503612-47-3 is useful as reference Impurity standard.
    Apixaban Open Chain Acid; 5-[[4-[3-(Aminocarbonyl)-1,4,5,7-tetrahydro-1-(4-methoxyphenyl)-7-oxo-6H-pyrazolo[3,4-c]pyridin-6-yl]phenyl]amino]pen tanoic Acid; 2206825-87-6; 503612-47-3
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    Product Name : N-Formyl Apixaban; N-Formyl-4,5,6,7-tetrahydro-1-(4-methoxyphenyl)-7-oxo-6-[4-(2-oxo-1-piperidinyl)phenyl]-1H-pyrazolo[3,4-c]pyridine-3-carboxamide;1351611-14-7

    Code: JCAPX-25
    CAS: 1351611-14-7
    Chemical Formula: C₂₆H₂₅N₅O₅
    Molecular Weight: 487.51
    Category: Apixaban Reference Standards/API Drug Metabolites/EP Impurities/USP Impurities
    Literature:
    Application: N-Formyl Apixaban; N-Formyl-4,5,6,7-tetrahydro-1-(4-methoxyphenyl)-7-oxo-6-[4-(2-oxo-1-piperidinyl)phenyl]-1H-pyrazolo[3,4-c]pyridine-3-carboxamide;1351611-14-7 is useful as reference Impurity standard.
    N-Formyl Apixaban; N-Formyl-4,5,6,7-tetrahydro-1-(4-methoxyphenyl)-7-oxo-6-[4-(2-oxo-1-piperidinyl)phenyl]-1H-pyrazolo[3,4-c]pyridine-3-carboxamide;1351611-14-7
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    Product Name : Apixaban Impurity J; Ethyl-6-( 4-( 5-chloropentamido )phenyl)-l-( 4-methoxyphenyl)-7 -oxo-4,5 ,6,7- tetrahydro-IH- pyrazolo[3,4-c]pyridine-3-carboxylate. (APB-IX ethyl ester) | 141823-20-2

    Code: JCAPX-24
    CAS:  141823-20-2
    Chemical Formula:C26H27ClN4O5
    Molecular Weight:510.98
    Category: Apixaban Reference Standards/Apixabin API Drug Metabolites/Apixabin EP Impurities/Apixabin USP Impurities
    Literature:
    Application:   Apixaban Impurity J; Ethyl-6-( 4-( 5-chloropentamido )phenyl)-l-( 4-methoxyphenyl)-7 -oxo-4,5 ,6,7- tetrahydro-IH- pyrazolo[3,4-c]pyridine-3-carboxylate. (APB-IX ethyl ester) | 141823-20-2 is useful as reference Impurity standard.
    Apixaban Impurity J; Ethyl-6-( 4-( 5-chloropentamido )phenyl)-l-( 4-methoxyphenyl)-7 -oxo-4,5 ,6,7- tetrahydro-IH- pyrazolo[3,4-c]pyridine-3-carboxylate. (APB-IX ethyl ester) | 141823-20-2
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    Product Name : Apixaban Impurity I; Methyl-6-(4-(5-chloropentamido) phenyl)-1-(4-methoxyphenyl)-7 -oxo-4, 5, 6, 7- tetrahydro-lH- pyrazolo [3, 4-c] pyridine-3-carboxylate (APB-IX methyl ester) Synonyms: methyl 6-(4-(N-(4-chlorobutyl)carboxamido)phenyl)-1-(4-methoxyphenyl)-7-oxo-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxylate | 2133292-60-9

    Code: JCAPX-23
    CAS: 2133292-60-9
    Chemical Formula:C25H25ClN4O5
    Molecular Weight:496.95
    Category: Reference Standards/API Drug Metabolites/EP Impurities/USP Impurities
    Literature:
    Application:   Apixaban Impurity I; Methyl-6-(4-(5-chloropentamido) phenyl)-1-(4-methoxyphenyl)-7 -oxo-4, 5, 6, 7- tetrahydro-lH- pyrazolo [3, 4-c] pyridine-3-carboxylate (APB-IX methyl ester) Synonyms: methyl 6-(4-(N-(4-chlorobutyl)carboxamido)phenyl)-1-(4-methoxyphenyl)-7-oxo-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxylate | 2133292-60-9 is useful as reference Impurity standard.
    Apixaban Impurity I;  Methyl-6-(4-(5-chloropentamido) phenyl)-1-(4-methoxyphenyl)-7 -oxo-4, 5, 6, 7- tetrahydro-lH- pyrazolo [3, 4-c] pyridine-3-carboxylate (APB-IX methyl ester) Synonyms: methyl 6-(4-(N-(4-chlorobutyl)carboxamido)phenyl)-1-(4-methoxyphenyl)-7-oxo-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxylate | 2133292-60-9
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    Product Name : Apixaban Impurity E; 6-(4-(5-chloropenatamido) phenyl)-l-(4-methoxyphenyl)-7 -oxo-4, 5, 6, 7- tetrahydro-lH-pyrazolo [3, 4-c] pyridine-3-carboxamide. (APB-IX)Apixaban Impurity 19; 6-(4-(5-Chloropentanamido)phenyl)-1-(4-methoxyphenyl)-7-oxo-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxamide | 1449510-64-8

    Code: JCAPX-22
    CAS: 1449510-64-8
    Chemical Formula:C25H26ClN5O4
    Molecular Weight:495.96
    Category: Apixaban Reference Standards/Apixabin API Drug Metabolites/Apixabin EP Impurities/Apixabin USP Impurities
    Literature:
    Application:   Apixaban Impurity E; 6-(4-(5-chloropenatamido) phenyl)-l-(4-methoxyphenyl)-7 -oxo-4, 5, 6, 7- tetrahydro-lH-pyrazolo [3, 4-c] pyridine-3-carboxamide. (APB-IX)Apixaban Impurity 19; 6-(4-(5-Chloropentanamido)phenyl)-1-(4-methoxyphenyl)-7-oxo-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxamide | 1449510-64-8is useful as reference Impurity standard.
    Apixaban Impurity E; 6-(4-(5-chloropenatamido) phenyl)-l-(4-methoxyphenyl)-7 -oxo-4, 5, 6, 7- tetrahydro-lH-pyrazolo [3, 4-c] pyridine-3-carboxamide. (APB-IX)Apixaban Impurity 19; 6-(4-(5-Chloropentanamido)phenyl)-1-(4-methoxyphenyl)-7-oxo-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxamide   | 1449510-64-8
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    Product Name : Apixaban Impurity D; 1-(4-Ethoxyphenyl)-7 -oxo-6-(4-(2-oxopiperdin-l-y l) phenyl) 4, 5, 6, 7- tetrahydro-1H-pyrazolo [3, 4-c] pyridine-3-carboxamide. (Ethoxy Apixaban) |1928718-22-2

    Code: JCAPX-21
    CAS: 1928718-22-2
    Chemical Formula:C26H27N5O4
    Molecular Weight:473.53
    Category: Apixaban Reference Standards/Apixabin API Drug Metabolites/Apixabin EP Impurities/Apixabin USP Impurities
    Literature:
    Application:   Apixaban Impurity D; 1-(4-Ethoxyphenyl)-7 -oxo-6-(4-(2-oxopiperdin-l-y l) phenyl) 4, 5, 6, 7- tetrahydro-1H-pyrazolo [3, 4-c] pyridine-3-carboxamide. (Ethoxy Apixaban) |1928718-22-2is useful as reference Impurity standard.
    Apixaban Impurity D; 1-(4-Ethoxyphenyl)-7 -oxo-6-(4-(2-oxopiperdin-l-y l) phenyl) 4, 5, 6, 7- tetrahydro-1H-pyrazolo [3, 4-c] pyridine-3-carboxamide. (Ethoxy Apixaban)  |1928718-22-2
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    Product Name : Apixaban Impurity C; 1-(phenyl)-7 -oxo-6-(4-(2-oxopiperdin-l-yl) phenyl) 4, 5, 6, 7-tetrahydro-1H-pyrazolo [3, 4-c] pyridine-3 -carboxamide. (Desmethoxy Apixaban) Synonyms: Desmethoxy Apixaban ; 7-Oxo-6-(4-(2-oxopiperidin-1-yl)phenyl)-1-phenyl-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxamide |1801881-17-3

    Code: JCAPX-20
    CAS: 1801881-17-3
    Chemical Formula:C24H23N5O3
    Molecular Weight:429.5
    Category: Apixaban Reference Standards/Apixabin API Drug Metabolites/Apixabin EP Impurities/Apixabin USP Impurities
    Literature:
    Application:   Apixaban Impurity C; 1-(phenyl)-7 -oxo-6-(4-(2-oxopiperdin-l-yl) phenyl) 4, 5, 6, 7-tetrahydro-1H-pyrazolo [3, 4-c] pyridine-3 -carboxamide. (Desmethoxy Apixaban) Synonyms: Desmethoxy Apixaban ; 7-Oxo-6-(4-(2-oxopiperidin-1-yl)phenyl)-1-phenyl-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxamide |1801881-17-3is useful as reference Impurity standard.
    Apixaban Impurity C; 1-(phenyl)-7 -oxo-6-(4-(2-oxopiperdin-l-yl) phenyl) 4, 5, 6, 7-tetrahydro-1H-pyrazolo [3, 4-c] pyridine-3 -carboxamide. (Desmethoxy Apixaban) Synonyms: Desmethoxy Apixaban ; 7-Oxo-6-(4-(2-oxopiperidin-1-yl)phenyl)-1-phenyl-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxamide  |1801881-17-3
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    Product Name : Apixaban Impurity B; 6-(4-aminophenyl)-1-(4-methoxyphenyl)-7-oxo-4, 5, 6, 7-tetrahydro-1H-pyrazolo [3, 4-c] pyridine 3-carboxamide. ; 6-(4-Aminophenyl)-1-(4-methoxyphenyl)-7-oxo-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxamide | 1423803-24-0

    Code: JCAPX-19
    CAS: 1423803-24-0
    Chemical Formula:C20H19N5O3
    Molecular Weight:377.4
    Category: Reference Standards/API Drug Metabolites/EP Impurities/USP Impurities
    Literature:
    Application:   Apixaban Impurity B; 6-(4-aminophenyl)-1-(4-methoxyphenyl)-7-oxo-4, 5, 6, 7-tetrahydro-1H-pyrazolo [3, 4-c] pyridine 3-carboxamide. ; 6-(4-Aminophenyl)-1-(4-methoxyphenyl)-7-oxo-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxamide | 1423803-24-0is useful as reference Impurity standard.
    Apixaban Impurity B; 6-(4-aminophenyl)-1-(4-methoxyphenyl)-7-oxo-4, 5, 6, 7-tetrahydro-1H-pyrazolo [3, 4-c] pyridine 3-carboxamide. ; 6-(4-Aminophenyl)-1-(4-methoxyphenyl)-7-oxo-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxamide  | 1423803-24-0
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    Product Name : 3-Chloro-5,6-dihydro-1-(4-nitrophenyl)-2(1H)-pyridinone |536760-29-9

    Code: JCAPX-19
    CAS: 536760-29-9
    Chemical Formula:C11H9ClN2O3
    Molecular Weight:252.65
    Category: Apixaban Reference Standards/Apixaban API Drug Metabolites/Apixaban EP Impurities/Apixaban USP Impurities
    Literature:
    Application:   3-Chloro-5,6-dihydro-1-(4-nitrophenyl)-2(1H)-pyridinone |536760-29-9 is useful as reference Impurity standard.
    3-Chloro-5,6-dihydro-1-(4-nitrophenyl)-2(1H)-pyridinone |536760-29-9
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    Product Name : 1-(4-Aminophenyl)-3-chloro-5,6-dihydropyridin-2(1H)-one ;Apixaban Impurity; 1-(4-Aminophenyl)-3-chloro-5,6-dihydro-2(1H)-pyridinone |1801881-15-1

    Code: JCAPX-18
    CAS: 1801881-15-1
    Chemical Formula:C₁₁H₁₁ClN₂O
    Molecular Weight:222.67
    Category: Apixaban  Reference Standards/Apixaban  API Drug Metabolites/Apixaban  EP Impurities/Apixaban  USP Impurities
    Literature:
    Application:  1-(4-Aminophenyl)-3-chloro-5,6-dihydropyridin-2(1H)-one ;Apixaban Impurity; 1-(4-Aminophenyl)-3-chloro-5,6-dihydro-2(1H)-pyridinone |1801881-15-1 is useful as reference Impurity standard.
    1-(4-Aminophenyl)-3-chloro-5,6-dihydropyridin-2(1H)-one ;Apixaban Impurity; 1-(4-Aminophenyl)-3-chloro-5,6-dihydro-2(1H)-pyridinone |1801881-15-1
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    Product Name : Ethyl 6-[4-(5-chloro pentanamido)phenyl] ;Ethyl6-[4-(5-chloropentanamido)phenyl]1-(4-methoxyphenyl)-7-oxo-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carbox ylate |1421823-20-2

    Code: JCAPX-17
    CAS: 1421823-20-2
    Chemical Formula:C27H29ClN4O5
    Molecular Weight:525
    Category: Reference Standards/API Drug Metabolites/EP Impurities/USP Impurities
    Literature:
    Application:   Ethyl 6-[4-(5-chloro pentanamido)phenyl] ;Ethyl6-[4-(5-chloropentanamido)phenyl]1-(4-methoxyphenyl)-7-oxo-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carbox ylate |1421823-20-2is useful as reference Impurity standard.
    Ethyl 6-[4-(5-chloro pentanamido)phenyl] ;Ethyl6-[4-(5-chloropentanamido)phenyl]1-(4-methoxyphenyl)-7-oxo-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carbox ylate  |1421823-20-2
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    Product Name : Ethyl1-(4-methoxyphenyl)-6-(4-nitrophenyl)-7-oxo-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxylate |536759-91-8

    Code: JCAPX-16
    CAS: 536759-91-8
    Chemical Formula:C22H20N4O6
    Molecular Weight:436.42
    Category: Reference Standards/API Drug Metabolites/EP Impurities/USP Impurities
    Literature:
    Application:   Ethyl1-(4-methoxyphenyl)-6-(4-nitrophenyl)-7-oxo-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxylate |536759-91-8is useful as reference Impurity standard.
    Ethyl1-(4-methoxyphenyl)-6-(4-nitrophenyl)-7-oxo-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxylate |536759-91-8
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    Product Name : Ethyl6-[4-(5-bromopentanamido)phenyl]1-(4-methoxyphenyl)-7-oxo-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carbox ylate|881386-12-5

    Code: JCAPX-15
    CAS: 881386-12-5
    Chemical Formula:C27H29BrN4O5
    Molecular Weight:569.46
    Category: Reference Standards/API Drug Metabolites/EP Impurities/USP Impurities
    Literature:
    Application:  Ethyl6-[4-(5-bromopentanamido)phenyl]1-(4-methoxyphenyl)-7-oxo-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carbox ylate|881386-12-5 is useful as reference Impurity standard.
    Ethyl6-[4-(5-bromopentanamido)phenyl]1-(4-methoxyphenyl)-7-oxo-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carbox ylate|881386-12-5
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    Product Name : Apixaban Impurity (AXB30) ;(Z)-ethyl 2-chloro-2-(2-(4-methoxyphenyl)hydrazono)acetate|27143-07-3

    Code: JCAPX-14
    CAS: 27143-07-3
    Chemical Formula:  C₁₁H₁₃N₂O₃Cl
    Molecular Weight:256.69
    Category: Reference Standards/API Drug Metabolites/EP Impurities/USP Impurities
    Literature:
    Application:  Apixaban Impurity (AXB30) ;(Z)-ethyl 2-chloro-2-(2-(4-methoxyphenyl)hydrazono)acetate|27143-07-3 is useful as reference Impurity standard.
    Apixaban Impurity (AXB30)  ;(Z)-ethyl 2-chloro-2-(2-(4-methoxyphenyl)hydrazono)acetate|27143-07-3
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    Product Name : Apixaban 4-Chloro Analog;4,5,6,7-Tetrahydro-1-(4-chlorophenyl)-7-oxo-6-[4-(2-oxo-1-piperidinyl) phenyl]-1H-pyrazolo[3,4-c]pyridine-3-carboxamide; |2029205-64-7

    Code: JCAPX-13
    CAS: 2029205-64-7
    Chemical Formula:C24H22ClN5O3
    Molecular Weight:463.92
    Category: Reference Standards/API Drug Metabolites/EP Impurities/USP Impurities
    Literature:
    Application: Apixaban 4-Chloro Analog;4,5,6,7-Tetrahydro-1-(4-chlorophenyl)-7-oxo-6-[4-(2-oxo-1-piperidinyl) phenyl]-1H-pyrazolo[3,4-c]pyridine-3-carboxamide; |2029205-64-7  is useful as reference Impurity standard.
    Apixaban 4-Chloro Analog;4,5,6,7-Tetrahydro-1-(4-chlorophenyl)-7-oxo-6-[4-(2-oxo-1-piperidinyl) phenyl]-1H-pyrazolo[3,4-c]pyridine-3-carboxamide; |2029205-64-7
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    Product Name : Apixaban Impurity 89 Synonym:(Z)-ethyl 2-chloro-2-(2-(4-methoxyphenyl)-2-nitrosohydrazono)acetate

    Code: JCAPX-12
    CAS: NA
    Chemical Formula: C11H11Cl3N2O3
    Molecular Weight: 325.5757
    Category: Reference Standards/API Drug Metabolites/EP Impurities/USP Impurities
    Literature:
    Application: Apixaban Impurity 89 Synonym:(Z)-ethyl 2-chloro-2-(2-(4-methoxyphenyl)-2-nitrosohydrazono)acetateis useful as reference Impurity standard.
    Apixaban Impurity 89 Synonym:(Z)-ethyl 2-chloro-2-(2-(4-methoxyphenyl)-2-nitrosohydrazono)acetate
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    Product Name : Apixaban ; 4,5,6,7-Tetrahydro-1-(4-methoxyphenyl)-7-oxo-6-[4-(2-oxo-1-piperidinyl) phenyl]-1H-pyrazolo[3,4-c]pyridine-3-carboxamide | 503612-47-3

    Code: JCAPX-11
    CAS: 503612-47-3
    Chemical Formula: C25H25N5O4
    Molecular Weight: 459.50
    Category: Reference Standards/API Drug Metabolites/EP Impurities/USP Impurities
    Literature:
    Application: Apixaban ; 4,5,6,7-Tetrahydro-1-(4-methoxyphenyl)-7-oxo-6-[4-(2-oxo-1-piperidinyl) phenyl]-1H-pyrazolo[3,4-c]pyridine-3-carboxamide | 503612-47-3 is useful as reference Impurity standard.
    Apixaban ; 4,5,6,7-Tetrahydro-1-(4-methoxyphenyl)-7-oxo-6-[4-(2-oxo-1-piperidinyl) phenyl]-1H-pyrazolo[3,4-c]pyridine-3-carboxamide  |  503612-47-3
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    Product Name : Apixaban 4,5-Dehydro Carboxamide ;Apixaban 4,5-Dehydro Amide ;6,7-Dihydro-1-(4-methoxyphenyl)-7-oxo-6-[4-(2-oxo-1-piperidinyl) phenyl]-1H-pyrazolo[3,4-c]pyridine-3-carboxamide | 1074549-89-5

    Code: JCAPX-10
    CAS: 1074549-89-5
    Chemical Formula: C25H23N5O4
    Molecular Weight: 457.48
    Category: Reference Standards/API Drug Metabolites/EP Impurities/USP Impurities
    Literature:
    Application: Apixaban 4,5-Dehydro Carboxamide ;Apixaban 4,5-Dehydro Amide ;6,7-Dihydro-1-(4-methoxyphenyl)-7-oxo-6-[4-(2-oxo-1-piperidinyl) phenyl]-1H-pyrazolo[3,4-c]pyridine-3-carboxamide | 1074549-89-5 is useful as reference Impurity standard.
    Apixaban 4,5-Dehydro Carboxamide ;Apixaban 4,5-Dehydro Amide ;6,7-Dihydro-1-(4-methoxyphenyl)-7-oxo-6-[4-(2-oxo-1-piperidinyl) phenyl]-1H-pyrazolo[3,4-c]pyridine-3-carboxamide  |  1074549-89-5
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    Product Name : Apixaban 4,5-Dehydro Carboxylic Acid ; 6,7-Dihydro-1-(4-methoxyphenyl)-7-oxo-6-[4-(2-oxo-1-piperidinyl) phenyl]-1H-pyrazolo[3,4-c]pyridine-3-carboxylic acid

    Code: JCAPX-09
    CAS: NA
    Chemical Formula: C25H22N4O5
    Molecular Weight: 458.47
    Category: Reference Standards/API Drug Metabolites/EP Impurities/USP Impurities
    Literature:
    Application: Apixaban 4,5-Dehydro Carboxylic Acid ; 6,7-Dihydro-1-(4-methoxyphenyl)-7-oxo-6-[4-(2-oxo-1-piperidinyl) phenyl]-1H-pyrazolo[3,4-c]pyridine-3-carboxylic acid is useful as reference Impurity standard.
    Apixaban 4,5-Dehydro Carboxylic Acid ; 6,7-Dihydro-1-(4-methoxyphenyl)-7-oxo-6-[4-(2-oxo-1-piperidinyl) phenyl]-1H-pyrazolo[3,4-c]pyridine-3-carboxylic acid
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    Product Name : Apixaban 4,5-Dehydro Carboxylic Acid Ethyl Ester ; 6,7-Dihydro-1-(4-methoxyphenyl)-7-oxo-6-[4-(2-oxo-1-piperidinyl) phenyl]-1H-pyrazolo[3,4-c]pyridine-3-carboxylic acid ethyl ester

    Code: JCAPX-08
    CAS: NA
    Chemical Formula: C27H26N4O5
    Molecular Weight: 486.52
    Category: Reference Standards/API Drug Metabolites/EP Impurities/USP Impurities
    Literature:
    Application: Apixaban 4,5-Dehydro Carboxylic Acid Ethyl Ester ; 6,7-Dihydro-1-(4-methoxyphenyl)-7-oxo-6-[4-(2-oxo-1-piperidinyl) phenyl]-1H-pyrazolo[3,4-c]pyridine-3-carboxylic acid ethyl ester  is useful as reference Impurity standard.
    Apixaban 4,5-Dehydro Carboxylic Acid Ethyl Ester ; 6,7-Dihydro-1-(4-methoxyphenyl)-7-oxo-6-[4-(2-oxo-1-piperidinyl) phenyl]-1H-pyrazolo[3,4-c]pyridine-3-carboxylic acid ethyl ester
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    Product Name : Apixaban Carboxylic Acid Impurity ;4,5,6,7-Tetrahydro-1-(4-methoxyphenyl)-7-oxo-6-[4-(2-oxo-1-piperidinyl) phenyl]-1H-pyrazolo[3,4-c]pyridine-3-carboxylic acid | 503614-92-4

    Code: JCAPX-07
    CAS: 503614-92-4
    Chemical Formula: C25H24N4O5
    Molecular Weight: 460.48
    Category: Reference Standards/API Drug Metabolites/EP Impurities/USP Impurities
    Literature:
    Application: Apixaban Carboxylic Acid Impurity ;4,5,6,7-Tetrahydro-1-(4-methoxyphenyl)-7-oxo-6-[4-(2-oxo-1-piperidinyl) phenyl]-1H-pyrazolo[3,4-c]pyridine-3-carboxylic acid | 503614-92-4 is useful as reference Impurity standard.
    Apixaban Carboxylic Acid Impurity ;4,5,6,7-Tetrahydro-1-(4-methoxyphenyl)-7-oxo-6-[4-(2-oxo-1-piperidinyl) phenyl]-1H-pyrazolo[3,4-c]pyridine-3-carboxylic acid  |  503614-92-4
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    Product Name : Apixaban Carboxylic Acid O-Desmethyl Impurity ;4,5,6,7-Tetrahydro-1-(4-hydroxyphenyl)-7-oxo-6-[4-(2-oxo-1-piperidinyl) phenyl]-1H-pyrazolo[3,4-c]pyridine-3-carboxylic acid

    Code: JCAPX-06
    CAS:  NA
    Chemical Formula: C24H22N4O5
    Molecular Weight: 446.46
    Category: Reference Standards/API Drug Metabolites/EP Impurities/USP Impurities
    Literature:
    Application: Apixaban Carboxylic Acid O-Desmethyl Impurity ;4,5,6,7-Tetrahydro-1-(4-hydroxyphenyl)-7-oxo-6-[4-(2-oxo-1-piperidinyl) phenyl]-1H-pyrazolo[3,4-c]pyridine-3-carboxylic acid is useful as reference Impurity standard.
    Apixaban Carboxylic Acid O-Desmethyl Impurity ;4,5,6,7-Tetrahydro-1-(4-hydroxyphenyl)-7-oxo-6-[4-(2-oxo-1-piperidinyl) phenyl]-1H-pyrazolo[3,4-c]pyridine-3-carboxylic acid
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    Product Name : Apixaban Chloro Impurity ;4,5,6,7-Tetrahydro-1-(4-chlorophenyl)-7-oxo-6-[4-(2-oxo-1-piperidinyl) phenyl]-1H-pyrazolo[3,4-c]pyridine-3-carboxamide

    Code: JCAPX-05
    CAS: NA
    Chemical Formula: C24H22ClN5O3
    Molecular Weight: 463.92
    Category: Reference Standards/API Drug Metabolites/EP Impurities/USP Impurities
    Literature:
    Application: Apixaban Chloro Impurity ;4,5,6,7-Tetrahydro-1-(4-chlorophenyl)-7-oxo-6-[4-(2-oxo-1-piperidinyl) phenyl]-1H-pyrazolo[3,4-c]pyridine-3-carboxamide is useful as reference Impurity standard.
    Apixaban Chloro Impurity ;4,5,6,7-Tetrahydro-1-(4-chlorophenyl)-7-oxo-6-[4-(2-oxo-1-piperidinyl) phenyl]-1H-pyrazolo[3,4-c]pyridine-3-carboxamide
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    Product Name : Apixaban Ethyl Ester Impurity ; 4,5,6,7-Tetrahydro-1-(4-methoxyphenyl)-7-oxo-6-[4-(2-oxo-1-piperidinyl) phenyl]-1H-pyrazolo[3,4-c]pyridine-3-carboxylic acid ethyl ester | 503614-91-3

    Code: JCAPX-04
    CAS: 503614-91-3
    Chemical Formula: C27H28N4O5
    Molecular Weight: 488.54
    Category: Reference Standards/API Drug Metabolites/EP Impurities/USP Impurities
    Literature:
    Application: Apixaban Ethyl Ester Impurity ; 4,5,6,7-Tetrahydro-1-(4-methoxyphenyl)-7-oxo-6-[4-(2-oxo-1-piperidinyl) phenyl]-1H-pyrazolo[3,4-c]pyridine-3-carboxylic acid ethyl ester | 503614-91-3 is useful as reference Impurity standard.
    Apixaban Ethyl Ester Impurity ; 4,5,6,7-Tetrahydro-1-(4-methoxyphenyl)-7-oxo-6-[4-(2-oxo-1-piperidinyl) phenyl]-1H-pyrazolo[3,4-c]pyridine-3-carboxylic acid ethyl ester  |  503614-91-3
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    Product Name : Apixaban Isopropyl Ester Impurity ;4,5,6,7-Tetrahydro-1-(4-methoxyphenyl)-7-oxo-6-[4-(2-oxo-1-piperidinyl) phenyl]-1H-pyrazolo[3,4-c]pyridine-3-carboxylic acid isopropyl ester

    Code: JCAPX-03
    CAS: NA
    Chemical Formula: C28H30N4O5
    Molecular Weight: 502.56
    Category: Reference Standards/API Drug Metabolites/EP Impurities/USP Impurities
    Literature:
    Application: Apixaban Isopropyl Ester Impurity ;4,5,6,7-Tetrahydro-1-(4-methoxyphenyl)-7-oxo-6-[4-(2-oxo-1-piperidinyl) phenyl]-1H-pyrazolo[3,4-c]pyridine-3-carboxylic acid isopropyl ester is useful as reference Impurity standard.
    Apixaban Isopropyl Ester Impurity ;4,5,6,7-Tetrahydro-1-(4-methoxyphenyl)-7-oxo-6-[4-(2-oxo-1-piperidinyl) phenyl]-1H-pyrazolo[3,4-c]pyridine-3-carboxylic acid isopropyl ester
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    Product Name : Apixaban O-Desmethyl Impurity ;4,5,6,7-Tetrahydro-1-(4-hydroxyphenyl)-7-oxo-6-[4-(2-oxo-1-piperidinyl) phenyl]-1H-pyrazolo[3,4-c]pyridine-3-carboxamide | 503612-76-8

    Code: JCAPX-02
    CAS: 503612-76-8
    Chemical Formula: C24H23N5O4
    Molecular Weight: 445.47
    Category: Reference Standards/API Drug Metabolites/EP Impurities/USP Impurities
    Literature:
    Application: Apixaban O-Desmethyl Impurity ;4,5,6,7-Tetrahydro-1-(4-hydroxyphenyl)-7-oxo-6-[4-(2-oxo-1-piperidinyl) phenyl]-1H-pyrazolo[3,4-c]pyridine-3-carboxamide | 503612-76-8 is useful as reference Impurity standard.
    Apixaban O-Desmethyl Impurity ;4,5,6,7-Tetrahydro-1-(4-hydroxyphenyl)-7-oxo-6-[4-(2-oxo-1-piperidinyl) phenyl]-1H-pyrazolo[3,4-c]pyridine-3-carboxamide  |  503612-76-8
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    Product Name : Apixaban Methyl Ester Impurity ;4,5,6,7-Tetrahydro-1-(4-methoxyphenyl)-7-oxo-6-[4-(2-oxo-1-piperidinyl) phenyl]-1H-pyrazolo[3,4-c]pyridine-3-carboxylic acid methyl ester | 1074365-84-6

    Code: JCAPX-01
    CAS: 1074365-84-6
    Chemical Formula: C26H26N4O5
    Molecular Weight: 474.51
    Category: Reference Standards/API Drug Metabolites/EP Impurities/USP Impurities
    Literature:
    Application: Apixaban Methyl Ester Impurity ;4,5,6,7-Tetrahydro-1-(4-methoxyphenyl)-7-oxo-6-[4-(2-oxo-1-piperidinyl) phenyl]-1H-pyrazolo[3,4-c]pyridine-3-carboxylic acid methyl ester | 1074365-84-6 is useful as reference Impurity standard.
    Apixaban Methyl Ester Impurity ;4,5,6,7-Tetrahydro-1-(4-methoxyphenyl)-7-oxo-6-[4-(2-oxo-1-piperidinyl) phenyl]-1H-pyrazolo[3,4-c]pyridine-3-carboxylic acid methyl ester  |  1074365-84-6