abacavir Impurity-1

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Abacavir is a 2,6-diaminopurine that is (1S)-cyclopent-2-en-1-ylmethanol in which the pro-R hydrogen at the 4-position is substituted by a 2-amino-6-(cyclopropylamino)-9H-purin-9-yl group. A nucleoside analogue reverse transcriptase inhibitor (NRTI) with antiretroviral activity (Ref: pubschem). Abacavir API Reference standards  and its EP Impurities, USP Impurities, non pharmacopeial Impurities, listed below & also offered custom synthesis for unknown Impurities. If require any contact info@drjcrbio.com, sales@drjcrbio.com

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    Product Name : Abacavir Impurity 1 ; N-(2-amino-4-chloro-6-((-4-(hydroxymethyl)cyclopent-2-en-1-yl)amino)pyrimidin-5-yl)formamide | 171887-04-0

    Code: JCABV-11
    CAS: 171887-04-0
    Chemical Formula: C11H14ClN5O2
    Molecular Weight: 283.71
    Category: Reference Standards/API Drug Metabolites/EP Impurities/USP Impurities
    Literature: GRANULES INDIA LIMITED; CHIGURUPATI, KRISHNA PRASAD; VETUKURI, PRASAD RAJU VNKV; GILLA, GOVERDHAN; BHUPATHI, RAJASEKHAR US2017/233329, 2017, A1 Location in patent: Paragraph 0050; 0051, Daluge, Susan M.; Martin, Michael T.; Sickles, Barry R.; Livingston, Douglas A. [Nucleosides, nucleotides and nucleic acids, 2000, vol. 19, # 1-2, p. 297 - 327]
    Application:Abacavir Impurity 1 ; N-(2-amino-4-chloro-6-((-4-(hydroxymethyl)cyclopent-2-en-1-yl)amino)pyrimidin-5-yl)formamide | 171887-04-0 is useful as reference Impurity standard.
    Abacavir Impurity 1 ; N-(2-amino-4-chloro-6-((-4-(hydroxymethyl)cyclopent-2-en-1-yl)amino)pyrimidin-5-yl)formamide | 171887-04-0
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