Abacavir

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Abacavir is a 2,6-diaminopurine that is (1S)-cyclopent-2-en-1-ylmethanol in which the pro-R hydrogen at the 4-position is substituted by a 2-amino-6-(cyclopropylamino)-9H-purin-9-yl group. A nucleoside analogue reverse transcriptase inhibitor (NRTI) with antiretroviral activity (Ref: pubschem). Abacavir API Reference standards  and its EP Impurities, USP Impurities, non pharmacopeial Impurities, listed below & also offered custom synthesis for unknown Impurities. If require any contact info@drjcrbio.com, sales@drjcrbio.com

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    Product Name : Impurity D trans Abacavir ;[(1R,4R)-4-[2-amino-6-(cyclopropylamino)-9H-purin-9-yl]cyclopent-2-enyl]methanol | 783292-37-5

    Code: JCABV-28
    CAS: 783292-37-5
    Chemical Formula: C14H18N6O
    Molecular Weight: 286.33
    Category: Reference Standards/API Drug Metabolites/EP Impurities/USP Impurities
    Literature:
    Application: Impurity D trans Abacavir ;[(1R,4R)-4-[2-amino-6-(cyclopropylamino)-9H-purin-9-yl]cyclopent-2-enyl]methanol | 783292-37-5  is useful as reference Impurity standard.
    Impurity D trans Abacavir ;[(1R,4R)-4-[2-amino-6-(cyclopropylamino)-9H-purin-9-yl]cyclopent-2-enyl]methanol | 783292-37-5
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    Product Name : (+)-Dibenzoyl-D-tartaric acid monohydrate | 80822-15-7

    Code: JCABV-27
    CAS: 80822-15-7
    Chemical Formula: C18H14O8·H2O
    Molecular Weight: 376.32
    Category: Reference Standards/API Drug Metabolites/EP Impurities/USP Impurities
    Literature:
    Application: (+)-Dibenzoyl-D-tartaric acid monohydrate | 80822-15-7 is useful as reference Impurity standard.
    (+)-Dibenzoyl-D-tartaric acid monohydrate  |  80822-15-7
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    Product Name : (1S-cis)-4-Amino-2-cyclopentene-1-methanol D-hydrogen tatrate | 229177-52-0

    Code: JCABV-26
    CAS: 229177-52-0
    Chemical Formula: C6H11NO.C4H6O6
    Molecular Weight: 263.24
    Category: Reference Standards/API Drug Metabolites/EP Impurities/USP Impurities
    Literature:
    Application: (1S-cis)-4-Amino-2-cyclopentene-1-methanol D-hydrogen tatrate | 229177-52-0 is useful as reference Impurity standard.
    (1S-cis)-4-Amino-2-cyclopentene-1-methanol D-hydrogen tatrate  |  229177-52-0
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    Product Name : N-(2-Amino-4,6-dichloropyrimidin-5-yl)formamide; Abacavir – In House Impurity; 171887-03-9

    Code: JCABV-25
    CAS: 171887-03-9
    Chemical Formula: C5H4Cl2N4O
    Molecular Weight: 207.01
    Category: Reference Standards/API Drug Metabolites/EP Impurities/USP Impurities
    Literature:
    Application: N-(2-Amino-4,6-dichloropyrimidin-5-yl)formamide; Abacavir - In House Impurity; 171887-03-9 is useful as reference Impurity standard.
    N-(2-Amino-4,6-dichloropyrimidin-5-yl)formamide; Abacavir - In House Impurity; 171887-03-9
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    Product Name : 2,5-Diamino-4,6-dihydroxypyrimidine hydrochloride; 56830-58-1; 40769-69-5; 56830-58-1

    Code: JCABV-24
    CAS: 56830-58-1/70080-76-1
    Chemical Formula: C4H6N4O2.HCl
    Molecular Weight: 178.58
    Category: Reference Standards/API Drug Metabolites/EP Impurities/USP Impurities
    Literature:
    Application: 2,5-Diamino-4,6-dihydroxypyrimidine hydrochloride | 56830-58-1 is useful as reference Impurity standard.
    2,5-Diamino-4,6-dihydroxypyrimidine hydrochloride; 56830-58-1; 40769-69-5; 56830-58-1
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    Product Name : O-t-Butyl Derivative Abacavir (USP); Abacavir t-Butyl Ether; 6-(Cyclopropylamino)-9-[(1R,4S)-4-[[(1,1-dimethylethyl)oxy]methyl]cyclopent-2-enyl]-9H-purine-2-amine ; 1443421-68-8

    Code: JCABV-23
    CAS: 1443421-68-8
    Chemical Formula: C18H26N6O
    Molecular Weight: 342.44
    Category: Reference Standards/API Drug Metabolites/EP Impurities/USP Impurities
    Literature: Nucleosides, nucleotides and nucleic acids, 2000, vol. 19, # 1-2, p. 297 - 327; CN107641122, 2018, A, Location in patent: Paragraph 0079-0080
    Application:O-t-Butyl Derivative Abacavir (USP) ; Abacavir t-Butyl Ether ; 6-(Cyclopropylamino)-9-[(1R,4S)-4-[[(1,1-dimethylethyl)oxy]methyl]cyclopent-2-enyl]-9H-purine-2-amine; Cas no 1443421-68-8 is useful as reference Impurity standard.
    O-t-Butyl Derivative Abacavir (USP); Abacavir t-Butyl Ether;  6-(Cyclopropylamino)-9-[(1R,4S)-4-[[(1,1-dimethylethyl)oxy]methyl]cyclopent-2-enyl]-9H-purine-2-amine ; 1443421-68-8
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    Product Name : Abacavir EP Impurity C; Abacavir USP RC A; Descyclopropyl Abacavir (USP); (1S,4R)-4-(2,6-Diamino-9H-purin-9-yl)cyclopent-2-enyl]methanol; 124752-25-6

    Code: JCABV-22
    CAS: 124752-25-6; 906626-51-5
    Chemical Formula: C11H14N6O
    Molecular Weight: 246.27
    Category: Reference Standards/API Drug Metabolites/abacavir EP Impurities/abacavir USP Impurities
    Literature: WO2009/21114, 2009, A1, Location in patent: Page/Page column 44, 47; Ando, Takayuki; Iwata, Masafumi; Zulfiqar, Fazila; Miyamoto, Tatsuya; Nakanishi, Masayuki; Kitade, Yukio [Bioorganic and Medicinal Chemistry, 2008, vol. 16, # 7, p. 3809 - 3815]; Vince; Brownell; Beers [Nucleosides and Nucleotides, 1995, vol. 14, # 1-2, p. 39 - 44]
    Application: Abacavir RC A; Abacavir Impurity C; Des cyclopropyl abacavir; [4-(2,6-diamino-9H-purin-9-yl)cyclopent-2-enyl]methanol; 124752-25-6; 906626-51-5 is useful as reference Impurity standard.
    Abacavir EP Impurity C; Abacavir USP RC A; Descyclopropyl Abacavir (USP); (1S,4R)-4-(2,6-Diamino-9H-purin-9-yl)cyclopent-2-enyl]methanol; 124752-25-6
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    Product Name : Abacavir nitraso Impurity; 5-amino-2-nitrosobenzene-1,3-diol

    Code: JCABV-21
    CAS: NA
    Chemical Formula: C6H6N2O3
    Molecular Weight: 154.12
    Category: Reference Standards/API Drug Metabolites/EP Impurities/USP Impurities
    Literature: Bioorganic and Medicinal Chemistry Letters, 2010, vol. 20, # 6, p. 1854 - 1857; Journal of the Chemical Society, 1896, vol. 69, p. 1323
    Application:Abacavir nitraso Impurity; 5-amino-2-nitrosobenzene-1,3-diol is useful as reference Impurity standard.
    Abacavir nitraso Impurity; 5-amino-2-nitrosobenzene-1,3-diol
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    Product Name : Abacavir formylated O-ethoxy Impurity ; N-(4-((4S)-4-(ethoxymethyl)cyclopent-2-enylamino)-2-amino-6-chloropyrimidin-5-yl)formamide

    Code: JCABV-20
    CAS: NA
    Chemical Formula: C16H26ClN5O2
    Molecular Weight: 355.86
    Category: Reference Standards/API Drug Metabolites/EP Impurities/USP Impurities
    Literature:
    Application: Abacavir formylated O-ethoxy Impurity ; N-(4-((4S)-4-(ethoxymethyl)cyclopent-2-enylamino)-2-amino-6-chloropyrimidin-5-yl)formamide is useful as reference Impurity standard.
    Abacavir formylated O-ethoxy Impurity ; N-(4-((4S)-4-(ethoxymethyl)cyclopent-2-enylamino)-2-amino-6-chloropyrimidin-5-yl)formamide
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    Product Name : Abacavir carbovir Impurity ; 2-amino-9-((1R,4S)-4-(hydroxymethyl)cyclopent-2-en-1-yl)-5,9-dihydro-6H-purin-6-one

    Code: JCABV-19
    CAS: NA
    Chemical Formula: C11H13N5O2
    Molecular Weight: 247.25
    Category: Reference Standards/API Drug Metabolites/EP Impurities/USP Impurities
    Literature: Exall, Anne M.; Jones, Martin F.; Mo, Chi-Leung; Myers, Peter L.; Paternoster, Ian L.; et al. [Journal of the Chemical Society. Perkin transactions I, 1991, # 10, p. 2467 - 2477] , Roy, Biswajit G.; Jana, Prithwish K.; Achari, Basudeb; Mandal, Sukhendu B. [Tetrahedron Letters, 2007, vol. 48, # 9, p. 1563 - 1566] ,Vince; Brownell; Beers [Nucleosides and Nucleotides, 1995, vol. 14, # 1-2, p. 39 - 44]
    Application: Abacavir carbovir Impurity ; 2-amino-9-((1R,4S)-4-(hydroxymethyl)cyclopent-2-en-1-yl)-5,9-dihydro-6H-purin-6-oneis useful as reference Impurity standard.
    Abacavir carbovir Impurity ; 2-amino-9-((1R,4S)-4-(hydroxymethyl)cyclopent-2-en-1-yl)-5,9-dihydro-6H-purin-6-one
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    Product Name : Abacavir CABS methyl ester; methyl 4-((2-amino-6-chloro-5-formamidopyrimidin-4-yl)amino)cyclopent-2-ene-1-carboxylate

    Code: JCABV-18
    CAS: NA
    Chemical Formula: C12H14ClN5O3
    Molecular Weight: 311.72
    Category: Reference Standards/API Drug Metabolites/EP Impurities/USP Impurities
    Literature:
    Application: Abacavir CABS methyl ester; methyl 4-((2-amino-6-chloro-5-formamidopyrimidin-4-yl)amino)cyclopent-2-ene-1-carboxylate is useful as reference Impurity standard.
    Abacavir CABS methyl ester; methyl 4-((2-amino-6-chloro-5-formamidopyrimidin-4-yl)amino)cyclopent-2-ene-1-carboxylate
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    Product Name : ((1S,4R)-4-(2-amino-6-(cyclopropylamino)-9H-purin-9-yl)cyclopent-2-enyl)methanol

    Code: JCABV-17
    CAS: 136470-78-5
    Chemical Formula: C14H18N6O
    Molecular Weight: 286.33
    Category: Reference Standards/API Drug Metabolites/EP Impurities/USP Impurities
    Literature: 
    Application: ((1S,4R)-4-(2-amino-6-(cyclopropylamino)-9H-purin-9-yl)cyclopent-2-enyl)methanol is useful as reference Impurity standard.
    ((1S,4R)-4-(2-amino-6-(cyclopropylamino)-9H-purin-9-yl)cyclopent-2-enyl)methanol
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    Product Name : Abacavir O-acetyl derivative; ((1S,4R)-4-(2-amino-6-(cyclopropylamino)-9H-purin-9-yl)cyclopent-2-enyl)methyl acetate

    Code: JCABV-16
    CAS: NA
    Chemical Formula: C16H20N6O2
    Molecular Weight: 328.37
    Category: Reference Standards/API Drug Metabolites/EP Impurities/USP Impurities
    Literature: Crimmins; King; Zuercher; Choy [Journal of Organic Chemistry, 2000, vol. 65, # 25, p. 8499 - 8509] ,
    Application: Abacavir O-acetyl derivative; ((1S,4R)-4-(2-amino-6-(cyclopropylamino)-9H-purin-9-yl)cyclopent-2-enyl)methyl acetateis useful as reference Impurity standard.
    Abacavir O-acetyl derivative; ((1S,4R)-4-(2-amino-6-(cyclopropylamino)-9H-purin-9-yl)cyclopent-2-enyl)methyl acetate
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    Product Name : 4,6-dichloropyrimidine-2,5-diamine; 2,5-Diamino-4,6-dichloroyrimidine | 55583-59-0

    Code: JCABV-15
    CAS: 55583-59-0
    Chemical Formula: C4H4Cl2N4
    Molecular Weight: 177.98
    Category: Reference Standards/API Drug Metabolites/EP Impurities/USP Impurities
    Literature:
    Application: 4,6-dichloropyrimidine-2,5-diamine; 2,5-Diamino-4,6-dichloroyrimidine | 55583-59-0 is useful as reference Impurity standard.
    4,6-dichloropyrimidine-2,5-diamine; 2,5-Diamino-4,6-dichloroyrimidine | 55583-59-0
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    Product Name : ((1S,4R)-4-(2-amino-6-ethoxy-9H-purin-9-yl)cyclopent-2-enyl)methanol hydrochloride

    Code: JCABV-14
    CAS: NA
    Chemical Formula: C13H17N5O2
    Molecular Weight: 275.31
    Category: Reference Standards/API Drug Metabolites/EP Impurities/USP Impurities
    Literature:
    Application: ((1S,4R)-4-(2-amino-6-ethoxy-9H-purin-9-yl)cyclopent-2-enyl)methanol hydrochloride is useful as reference Impurity standard.
    ((1S,4R)-4-(2-amino-6-ethoxy-9H-purin-9-yl)cyclopent-2-enyl)methanol hydrochloride
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    Product Name : ((1S,4R)-4-(2,5-diamino-6-chloropyrimidin-4-ylamino)cyclopent-2-enyl)methanol

    Code: JCABV-13
    CAS: 141271-12-7
    Chemical Formula: C10H14ClN5O
    Molecular Weight: 255.7
    Category: Reference Standards/API Drug Metabolites/EP Impurities/USP Impurities
    Literature:
    Application:  ((1S,4R)-4-(2,5-diamino-6-chloropyrimidin-4-ylamino)cyclopent-2-enyl)methanol is useful as reference Impurity standard.
    ((1S,4R)-4-(2,5-diamino-6-chloropyrimidin-4-ylamino)cyclopent-2-enyl)methanol
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    Product Name : N-(2-amino-4,6-dichloropyrimidin-5-yl)formamide

    Code: JCABV-12
    CAS: 171887-03-9
    Chemical Formula: C5H4Cl2N4O
    Molecular Weight: 207.02
    Category: Reference Standards/API Drug Metabolites/EP Impurities/USP Impurities
    Literature:
    Application:  N-(2-amino-4,6-dichloropyrimidin-5-yl)formamide is useful as reference Impurity standard.
    N-(2-amino-4,6-dichloropyrimidin-5-yl)formamide
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    Product Name : Abacavir Impurity 1 ; N-(2-amino-4-chloro-6-((-4-(hydroxymethyl)cyclopent-2-en-1-yl)amino)pyrimidin-5-yl)formamide | 171887-04-0

    Code: JCABV-11
    CAS: 171887-04-0
    Chemical Formula: C11H14ClN5O2
    Molecular Weight: 283.71
    Category: Reference Standards/API Drug Metabolites/EP Impurities/USP Impurities
    Literature: GRANULES INDIA LIMITED; CHIGURUPATI, KRISHNA PRASAD; VETUKURI, PRASAD RAJU VNKV; GILLA, GOVERDHAN; BHUPATHI, RAJASEKHAR US2017/233329, 2017, A1 Location in patent: Paragraph 0050; 0051, Daluge, Susan M.; Martin, Michael T.; Sickles, Barry R.; Livingston, Douglas A. [Nucleosides, nucleotides and nucleic acids, 2000, vol. 19, # 1-2, p. 297 - 327]
    Application:Abacavir Impurity 1 ; N-(2-amino-4-chloro-6-((-4-(hydroxymethyl)cyclopent-2-en-1-yl)amino)pyrimidin-5-yl)formamide | 171887-04-0 is useful as reference Impurity standard.
    Abacavir Impurity 1 ; N-(2-amino-4-chloro-6-((-4-(hydroxymethyl)cyclopent-2-en-1-yl)amino)pyrimidin-5-yl)formamide  |  171887-04-0
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    Product Name : (1S,4R)-(4-Aminocyclopent-2-enyl)methanol hydrochloride; 168960-19-8

    Code: JCABV-10
    CAS: 168960-19-8
    Chemical Formula: C6H12ClNO
    Molecular Weight:149.62
    Category: Reference Standards/API Drug Metabolites/EP Impurities/USP Impurities
    Literature:  (1) Shuto, S., et al.: J. Med. Chem., 46, 4741 (2003); 2) Shuto, S., et al.: Curr. Med. Chem., 11, 827 (2004) (3) Kudoh, T., et al.: Nucleosides Nucleotides Nucleic Acids 24, 655 (2005)
    Application: (1S,4R)-(4-Aminocyclopent-2-enyl)methanol hydrochloride | 168960-19-8 is useful as reference Impurity standard.
    (1S,4R)-(4-Aminocyclopent-2-enyl)methanol hydrochloride; 168960-19-8
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    Product Name : Abacavir side chain dimer; CABS-1 Side chain dimer

    Code: JCABV-09
    CAS: NA
    Chemical Formula: C17H22N6O2
    Molecular Weight: 342.4
    Category: Reference Standards/API Drug Metabolites/EP Impurities/USP Impurities
    Literature: METHODS AND COMPOSITIONS FOR ENZYME LINKED IMMUNO AND HYBRIDIZATION MASS SPECTROMETRIC ASSAY YYZ Pharmatech, Inc.; Marshall, John G.; Florentinus, Angelica Kirsten - US2016/223530, 2016, A1 Patent Family Members: WO2014/186874 A1; US2016/223530 A1 ,Antony, Suresh J.; Davis, Michelle A.; Davis, Monique G.; Almaghlouth, Nouf K.; Guevara, Roberto; Omar, Fahad; Del Rey, Fernando; (…) Antony, Nishaal; Prakash, Bharat V. [Journal of Medical Virology, 2021, vol. 93, # 1, p. 491 - 498]
    Application: Abacavir side chain dimer ; CABS-1 Side chain dimer is useful as reference Impurity standard.
    Abacavir side chain dimer; CABS-1 Side chain dimer
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    Product Name : Abacavir EP Impurity E; Dehydro abacavir; ((1R,3S)-3-(2-amino-6-(cyclopropylamino)-9H-purin-9-yl)cyclopentyl)methanol; 208762-35-0

    Code: JCABV-08
    CAS: 208762-35-0
    Chemical Formula: C14H20N6O
    Molecular Weight: 288.35
    Category: Reference Standards/API Drug Metabolites/EP Impurities/USP Impurities
    Literature: Daluge, Susan M.; Martin, Michael T.; Sickles, Barry R.; Livingston, Douglas A. [Nucleosides, nucleotides and nucleic acids, 2000, vol. 19, # 1-2, p. 297 - 327],
    Application: Abacavir Impurity E ; Dehydro abacavir; ((1R,3S)-3-(2-amino-6-(cyclopropylamino)-9H-purin-9-yl)cyclopentyl)methanol | 208762-35-0 is useful as reference Impurity standard.
    Abacavir EP Impurity E; Dehydro abacavir; ((1R,3S)-3-(2-amino-6-(cyclopropylamino)-9H-purin-9-yl)cyclopentyl)methanol; 208762-35-0
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    Product Name : Abacavir EP Impurity B; Abacavir USP Related Compound D; Abacavir-USP O-pyrimidine derivative; N6-Cyclopropyl-9-((1R,4S)-4-(((2,5-diamino-6-chloropyrimidin-4-yl)oxy)methyl)cyclopent-2-en-1-yl)-9H-purine-2,6-diamine; (1S,4R)-4-[2-Amino-6-(cyclopopylamino)-9H-purin-9-yl]-1-(2,5-diamino-6-chloro-4-pyrimidinyloxy)methyl-2-cyclopentene; 1443421-69-9

    Code: JCABV-07
    CAS: 1443421-69-9
    Chemical Formula: C18H21ClN10O
    Molecular Weight: 428.88
    Category: Reference Standards/API Drug Metabolites/EP Impurities/USP Impurities
    Literature: https://pubchem.ncbi.nlm.nih.gov
    Application: Abacavir Impuirty-B; Abacavir-USP O-pyrimidine derivative; (1S,4R)-4-[2-Amino-6-(cyclopopylamino)-9H-purin-9-yl]-1-(2,5-diamino-6-chloro-4-pyrimidinyloxy)methyl-2-cyclopentene | 1443421-69-9is useful as reference Impurity standard.
    Abacavir EP Impurity B; Abacavir USP Related Compound D; Abacavir-USP O-pyrimidine derivative; N6-Cyclopropyl-9-((1R,4S)-4-(((2,5-diamino-6-chloropyrimidin-4-yl)oxy)methyl)cyclopent-2-en-1-yl)-9H-purine-2,6-diamine;   (1S,4R)-4-[2-Amino-6-(cyclopopylamino)-9H-purin-9-yl]-1-(2,5-diamino-6-chloro-4-pyrimidinyloxy)methyl-2-cyclopentene; 1443421-69-9
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    Product Name : Abacavir EP Impurity A; Abacavir enantiomer ; (1R,4S)-4-[2-amino-6-(cyclopropylamino)-9H-purin-9-yl}]-cyclopent-2-enyl}methanol ; (1R,4S)-Abacavir; Ent-Abacavir; CABS-3; 136470-79-6

    Code: JCABV-06
    CAS:136470-79-6
    Chemical Formula: C14H18N6O
    Molecular Weight: 286.33
    Category: Reference Standards/API Drug Metabolites/EP Impurities/USP Impurities
    Literature: Daluge, Susan M.; Martin, Michael T.; Sickles, Barry R.; Livingston, Douglas A. [Nucleosides, nucleotides and nucleic acids, 2000, vol. 19, # 1-2, p. 297 - 327],GRANULES INDIA LIMITED; CHIGURUPATI, KRISHNA PRASAD; VETUKURI, PRASAD RAJU VNKV; GILLA, GOVERDHAN; BHUPATHI, RAJASEKHAR US2017/233329, 2017, A1 Location in patent: Paragraph 0056; 0057; 0058; 0059; 0060
    Application:  Abacavir Impurity A ; Abacavir enantiomer ; (1R,4S)-4-[2-amino-6-(cyclopropylamino)-9H-purin-9-yl}]-cyclopent-2-enyl}methanol ; CABS-3 | 136470-79-6is useful as reference Impurity standard.
    Abacavir EP Impurity A; Abacavir enantiomer ; (1R,4S)-4-[2-amino-6-(cyclopropylamino)-9H-purin-9-yl}]-cyclopent-2-enyl}methanol ; (1R,4S)-Abacavir;  Ent-Abacavir; CABS-3; 136470-79-6
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    Product Name : Abacavir Impurity F; Abacavir tertiary butyl Impurity; N6-cyclopropyl-9-((1R,4S)-4-{[(1,1-dimethylethyl)oxy]methyl}-2-cyclopenten-1-yl)-9H-purine-2,6-diamine | 1443421-68-8

    Code: JCABV-05
    CAS: 1443421-68-8
    Chemical Formula: C18H26N6O
    Molecular Weight: 342.44
    Category: Reference Standards/API Drug Metabolites/EP Impurities/USP Impurities
    Literature:
    Application: Abacavir Impurity F; Abacavir tertiary butyl Impurity; N6-cyclopropyl-9-((1R,4S)-4-{[(1,1-dimethylethyl)oxy]methyl}-2-cyclopenten-1-yl)-9H-purine-2,6-diamine | 1443421-68-8 is useful as reference Impurity standard.
    Abacavir Impurity F; Abacavir tertiary butyl Impurity; N6-cyclopropyl-9-((1R,4S)-4-{[(1,1-dimethylethyl)oxy]methyl}-2-cyclopenten-1-yl)-9H-purine-2,6-diamine  |  1443421-68-8
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    Product Name : Abacavir Cyclopropyl Diamino Purine Impurity; Abacavir Impurity 1; N6-Cyclopropyl-9H-purine-2,6-diamine; 120503-69-7

    Code: JCABV-04
    CAS: 120503-69-7
    Chemical Formula: C8H10N6
    Molecular Weight: 190.21
    Category: Reference Standards/API Drug Metabolites/EP Impurities/USP Impurities
    Literature: Holy, Antonin; Votruba, Ivan; Tloustova, Eva; Masojidkova, Milena [Collection of Czechoslovak Chemical Communications, 2001, vol. 66, # 10, p. 1545 - 1592] , Crimmins; King; Zuercher; Choy [Journal of Organic Chemistry, 2000, vol. 65, # 25, p. 8499 - 8509]
    Application:  Abacavir Cyclopropyl Diamino Purine Impurity ; N6-Cyclopropyl-9H-purine-2,6-diamine | 120503-69-7 is useful as reference Impurity standard.
    Abacavir Cyclopropyl Diamino Purine Impurity; Abacavir Impurity 1; N6-Cyclopropyl-9H-purine-2,6-diamine; 120503-69-7
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    Product Name : Abacavir RC C; [(1S,4R)-4-(2-amino-6-chloro-9H-purin-9-yl)cyclopent-2-enyl]methanol hydrochloride; CABS-2; 172015-79-1

    Code: JCABV-03
    CAS: 172015-79-1
    Chemical Formula: C11H14ClN5O
    Molecular Weight: 267.72
    Category: Reference Standards/API Drug Metabolites/EP Impurities/USP Impurities
    Literature: Daluge, Susan M.; Martin, Michael T.; Sickles, Barry R.; Livingston, Douglas A. [Nucleosides, nucleotides and nucleic acids, 2000, vol. 19, # 1-2, p. 297 - 327],GRANULES INDIA LIMITED; CHIGURUPATI, KRISHNA PRASAD; VETUKURI, PRASAD RAJU VNKV; GILLA, GOVERDHAN; BHUPATHI, RAJASEKHAR US2017/233329, 2017, A1 Location in patent: Paragraph 0056; 0057; 0058; 0059; 0060
    Application:  Abacavir RC C ; [(1S,4R)-4-(2-amino-6-chloro-9H-purin-9-yl)cyclopent-2-enyl]methanol hydrochloride ; CABS-2 | 172015-79-1 is useful as reference Impurity standard.
    Abacavir RC C; [(1S,4R)-4-(2-amino-6-chloro-9H-purin-9-yl)cyclopent-2-enyl]methanol hydrochloride; CABS-2; 172015-79-1
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    Product Name : Abacavir Related Compound A; Abacavir Impurity C; Des cyclopropyl abacavir; [4-(2,6-diamino-9H-purin-9-yl)cyclopent-2-enyl]methanol; 124752-25-6; 906626-51-5

    Code: JCABV-02
    CAS: 124752-25-6; 906626-51-5
    Chemical Formula: C11H14N6O
    Molecular Weight: 246.27
    Category: Reference Standards/API Drug Metabolites/abacavir EP Impurities/abacavir USP Impurities
    Literature: WO2009/21114, 2009, A1, Location in patent: Page/Page column 44, 47; Ando, Takayuki; Iwata, Masafumi; Zulfiqar, Fazila; Miyamoto, Tatsuya; Nakanishi, Masayuki; Kitade, Yukio [Bioorganic and Medicinal Chemistry, 2008, vol. 16, # 7, p. 3809 - 3815]; Vince; Brownell; Beers [Nucleosides and Nucleotides, 1995, vol. 14, # 1-2, p. 39 - 44]
    Application: Abacavir RC A; Abacavir Impurity C; Des cyclopropyl abacavir; [4-(2,6-diamino-9H-purin-9-yl)cyclopent-2-enyl]methanol; 124752-25-6; 906626-51-5 is useful as reference Impurity standard.
    Abacavir Related Compound A; Abacavir Impurity C; Des cyclopropyl abacavir; [4-(2,6-diamino-9H-purin-9-yl)cyclopent-2-enyl]methanol; 124752-25-6; 906626-51-5
  • Free

    Product Name : Abacavir RC B; [4-(2,5-diamino-6-chloropyrimidin-4-ylamino)cyclopent-2-enyl]methanol | 141271-12-7

    Code: JCABV-01
    CAS: 141271-12-7
    Chemical Formula:C10H14ClN5O
    Molecular Weight: 255.7
    Category: Reference Standards/API Drug Metabolites/EP Impurities/USP Impurities
    Literature: Evans, Chris T.; Roberts, Stanley M.; Shoberu, Karoline A.; Sutherland, Alan G. [Journal of the Chemical Society. Perkin transactions I, 1992, # 5, p. 589 - 59
    Application:  Abacavir RC B ; [4-(2,5-diamino-6-chloropyrimidin-4-ylamino)cyclopent-2-enyl]methanol | 141271-11-6 is useful as reference Impurity standard.
    Abacavir RC B; [4-(2,5-diamino-6-chloropyrimidin-4-ylamino)cyclopent-2-enyl]methanol  |   141271-12-7