Carvedilol nitroso Impurity; N-(3-((9H-carbazol-4-yl)oxy)-2-hydroxypropyl)-N-(2-(2-methoxyphenoxy)ethyl)nitrous amide

Carvedilol

Description

Code: JCCRD-20
CAS:2248746-67-8
Chemical Formula: C24H25N3O5
Molecular Weight: 435.48
Category: Reference Standards/API Drug Metabolites/EP Impurities/USP Impurities
Literature:  WAIN, Christopher, Paul; WO2005/113502, 2005, A1; Location in patent: Page/Page column 15 / WO2009/116069, 2009, A2; Location in patent: Page/Page column 12
Application: Carvediolol nitroso is an impurity of Carvedilol – is a unique antihypertensive medication with activity against both alpha- and beta-adrenergic receptors